Results 91 to 100 of about 453,327 (300)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Identifying Code Injection and Reuse Payloads In Memory Error Exploits [PDF]
, 2014 Today's most widely exploited applications are the web browsers and document readers we use every day. The immediate goal of these attacks is to compromise target systems by executing a snippet of malicious code in the context of the exploited ...
Snow, Kevin
core +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
EMPIRICAL ASSESSMENT OF THE IMPACT OF USING AUTOMATIC STATIC ANALYSIS ON CODE QUALITY [PDF]
, 2013 Automatic static analysis (ASA) tools analyze the source or compiled code looking for violations of recommended programming practices (called issues) that might cause faults or might degrade some dimensions of software quality. Antonio Vetro' has focused
Vetro', Antonio
core +1 more source
Lingua Cultura, 2018 The study had two objectives, those were to investigate the use of code-mixing in the business emails which could be categorized as asynchronous computer-mediated communication, and to calculate the most prevalent occurrences of codemixing in the ...
Robby Andre
doaj +3 more sources
Problems and Controversy of the Tax Code of Ukraine in the Context of Monitoring of its Implementation Проблемы и разногласия Налогового кодекса Украины в контексте мониторинга его имплементации [PDF]
Problemi Ekonomiki, 2011 The article defines the concept of monitoring the implementation of the tax code of Ukraine, by identifying the problems the application of the tax code of Ukraine, reasonably methodical approach to monitoring the implementation of the tax code of ...
Ivanov Yuriy. B., Naidenko Aleksey Ye.,
doaj
Codes Identifying Vertices in Graphs
Electronic Notes in Discrete Mathematics, 2005 Abstract This talk deals with identifying codes in graphs. These codes we defined to model a problem of fault detection in multiprocessor systems. They are closely related to covering and superimposed codes. Very nice combinatorial questions arise from these codes, some of which we present during the talk.
openaire +1 more source