Results 91 to 100 of about 256,860 (287)
On the Density of Identifying Codes in the Square Lattice [PDF]
, 2002 Let G=(V, E) be an undirected graph and C a subset of vertices. If the sets Br(v)∩C, v∈V, are all nonempty and different, where Br(v) denotes the set of all points within distance r from v, we call C an r-identifying code.
Lobstein, Antoine, Honkala, Iiro
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Accuracy of national mortality codes in identifying adjudicated cardiovascular deaths [PDF]
, 2011 Objective: This study investigated the sensitivity and specificity of the national mortality codes in identifying cardiovascular disease (CVD) deaths and documents methods of verification.Methods: A 12-year retrospective case ascertainment of all ICD ...
D Magliano (13338792) +17 more
core +3 more sources
Identifying Codes and the Set Cover Problem [PDF]
, 2006 We consider the problem of finding a minimum identifying code in a graph, i.e., a designated set of vertices whose neighborhoods uniquely overlap at any vertex on the graph.
Moshe Laifenfeld +2 more
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
On identifying codes that are robust against edge changes [PDF]
, 2007 Assume that G=(V, E) is an undirected graph, and C⊆V. For every v∈V, denote Ir(G; v)={u∈C: d(u,v)≤r}, where d(u,v) denotes the number of edges on any shortest path from u to v in G.
Laihonen, Tero, Honkala, Iiro
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Medicine, 2017 Biobanks and national registries represent a powerful tool for genomic discovery, but rely on diagnostic codes that can be unreliable and fail to capture relationships between related diagnoses.
Thomas H. McCoy +4 more
doaj +1 more source