Results 111 to 120 of about 22,178 (297)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A survey on the security technology of edge computing

open access: yes大数据, 2019
With the continuous development of Internet of things applications,a large number of mobile terminal devices participate in service computing.Traditional cloud computing models cannot adapt to the rapid growth of data generated by network edge devices ...
Jie LING   +3 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Identity based cryptography from pairings. [PDF]

open access: yes, 2006
Yuen Tsz Hon.Thesis (M.Phil.)--Chinese University of Hong Kong, 2006.Includes bibliographical references (leaves 109-122).Abstracts in English and Chinese.Abstract --- p.iAcknowledgement --- p.iiiList of Notations --- p.viiiChapter 1 --- Introduction -

core  

The use of Fermat quotients in cryptography

open access: yes, 2023
Fermat quotients are based on Fermat’s little theorem. They possess properties that make them suitable for generating pseudo-random numbers. They can also be used to generate Boolean functions.
Agboola, Titilayo
core  

Identity/attribute-based authentication protocols based on pairings [PDF]

open access: yes, 2020
Authentication is one of the most important goals in cryptography. It provides sharing information with only authorized people and protecting data from being modified.
Öztürk, Gülnihal
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

A New authentication Mechanism and Key Agreement Protocol for SIP Using Identity-based Cryptography

open access: yes, 2006
The Session Initiation Protocol (SIP) protocol is commonly used to establish Voice over IP (VoIP) calls. IETF SIP standards do not specify a secure authentication process thus allowing malicious parties to impersonate other parties or to charge calls to ...
Looi, Mark H.   +7 more
core  

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