Results 131 to 140 of about 22,178 (297)

New Developments in Quasigroup-Based Cryptography

open access: yes, 2014
This chapter offers an overview of new developments in quasigroup-based cryptography, especially of new defined quasigroup-based block ciphers and stream ciphers, hash functions and message authentication codes, PRNGs, public key cryptosystems, etc ...
Mileva, Aleksandra
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

ID-based Secret-Key Cryptography

open access: yes, 1998
. This paper introduces ID-based secret-key cryptography, in which secret keys are privately and uniquely binded to an identity. This enables to extend publickey cryptography features at the high throughput rate of secret-key cryptography.
Sung-Ming Yen, Marc Joye
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Cryptographie de l'identité. (Identity-based cryptography).

open access: yes, 2018
During this Thesis we investigated the possibilities that Identity-based Encryption offers when used out of their original purpose. We managed to generalize a whole class of different identity-based encryption schemes into Downgradable Identity-based Encryptions. We found a generic way to construct Blind Identity-based Encryptions.
openaire   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Contributions to identity-based cryptography

open access: yes, 2015
In traditional public key cryptography, public keys of users are essentially random strings generated from random secret keys. Hence, public key certificates are required to attest to the relations between users' identities and their public keys.
Kefeng Wang (1418479)
core  

Security-Mediated Certificateless Cryptography

open access: yes, 2006
We introduce the notion of security-mediated certificateless (SMC) cryptography. This allows more lightweight versions of mediated cryptography while maintaining the ability for instantaneous revocation of keys.
Gonzalez Nieto, Juan M.   +5 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy