Results 141 to 150 of about 19,205 (250)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A New Era of Cryptography: Quantum Cryptography [PDF]
, 2017 Security is the first priority in today digital world for secure communication between sender and receiver. Various Cryptography techniques are developed time to time for secure communication.
Bhandari, Sandeepak
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Identity-Based Cryptography: Schemes and Implementations
This comprehensive paper presents a thorough analysis of Identity-Based Cryptography (IBC), focusing on both encryption (IBE) and signature (IBS) schemes, along with novel contributions in threshold implementations and zero-knowledge proofs. We provide detailed mathematical formulations and practical implementations of major IBE schemes including Boneh-
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
The privacy preserving framework with virtual ring and identity-based cryptography for Smart Grid [PDF]
, 2019 One of the main challenges in the smart grid is how to efficiently manage the high-volume data from smart meters and sensors and preserve the privacy from the consumption data to avoid potential attacks (e.g., identity theft) for the involved prosumers ...
Sutanto, Leonard
core
An Efficient Identity-Based Aggregate Signature Scheme
工程科学与技术, 2011 :Security analyses of an ID-based aggregate signature scheme presented by Song, Kim, Lee and Yoon were given in this paper. It is found that the scheme is universally forgeable.
Du Hong-Zhen
doaj
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
GAPS: GPU-accelerated processing service for SM9
CybersecuritySM9 was established in 2016 as a Chinese official identity-based cryptographic (IBC) standard, and became an ISO standard in 2021. It is well-known that IBC is suitable for Internet of Things (IoT) applications, since a centralized processing of client ...
Wenhan Xu, Hui Ma, Rui Zhang
doaj +1 more source