Results 131 to 140 of about 5,989,072 (355)

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Justifying an Adequate Response to the Vulnerable Other [PDF]

open access: yes, 2016
Is it possible to justify requiring that I respond adequately to the other’s vulnerability? I contend that insofar as I value my own personal identity it is consistent to respond adequately to the vulnerability of the other.
Chandra, Kavanagh
core  

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

AN ANALYSIS ON MALCOLM RIVER’S DISSOCIATIVE IDENTITY DISORDER IN IDENTITY MOVIE DIRECTED BY JAMES MANGOLD [PDF]

open access: yes, 2017
This project aims to analyze the character Malcolm River in Identity movie. The result of analyzing the figures Malcolm Riversis that he suffered multiple personality syndrome or now known as Dissociative Identity Disorder. Malcolm was abused, neglected,
Wibowo, Abdul RohimIndra
core   +1 more source

Publisher Correction: Methanol fixation is the method of choice for droplet-based single-cell transcriptomics of neural cells

open access: yesCommunications Biology, 2023
Ana Gutiérrez-Franco   +5 more
doaj   +1 more source

Demystifying authenticity: Behavioral and neurophysiological signatures of self-positivity for authentic and presented selves

open access: yesNeuroImage
Authenticity has captivated scholars. But what is it? An emerging view considers it exaggerated favorability (self-enhancement), whereas traditional views regard it as self-accuracy and self-consistency.
Chengli Huang   +7 more
doaj   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

Identity

open access: yes, 2015
This entry focuses on the role that the concept of identity has for framing, approaching, and possibly resolving moral dilemmas in bioethics. First, it introduces some of the key questions pertaining to the philosophical debate about identity. Second, it provides a synthetic overview of the main philosophical accounts of identity.
Annoni, Marco, BONIOLO, Giovanni
openaire   +1 more source

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