Results 131 to 140 of about 3,911,112 (360)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Learning to be: identity construction in online communities
When an individual enters a new field of practice, an integral part of that process is the development of an identity that situates the individual as a legitimate participant in that practice. This study combines elements of identity theory with theories
Smith, Mark
core
What makes an organisation's corporate identity attractive to its employees? A social identity perspective [PDF]
Corporate Identity provides the foundation for an organisation’s Corporate Brand, and managers need to understand how they can align the behaviour of their employees with that identity.
Maxwell, Rachael
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Racial & Identity Profiling Advisory Board Annual Report 2018
The Racial and Identity Profiling Advisory (RIPA) Board began its work in July 2016 as part of the Racial and Identity Profiling Act of 2015 (AB 953) with a momentous purpose: to eliminate racial and identity profiling and improve racial and identity ...
Racial & Identity Profiling Advisory Board
core
Truth, Beauty and Goodness: Dialogue with the Divine
The nature of Catholic schools is ever-changing, as they increasingly draw upon young people from a wide variety of social, cultural and religious backgrounds.
Anthony Cleary
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Embryo and prejudice: From diverse first transcriptional impressions to a common developmental path
Pre-implantation mammalian development culminates in the blastocyst, where embryonic and extra-embryonic tissue founders reside. However, species variations in the underlying mechanisms, starting from zygotic genome activation (ZGA), remain underexplored.
Guillaume Giraud Collet +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source

