Results 71 to 80 of about 18,601 (241)

Human-centred identity - from rhetoric to reality [PDF]

, 2010
This paper presents a proposal for human-centred identity management. Even though the term ‘human-centred identity’ has been widely used in the past few years, the solutions either descritbe a technical system for managing identity, or describe an ...
Sasse, MA, Rahaman, A
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Identity Management Systems for the Internet of Things: A Survey Towards Blockchain Solutions

Sensors, 2018
The Internet of Things aims at connecting everything, ranging from individuals, organizations, and companies to things in the physical and virtual world.
Xiaoyang Zhu, Youakim Badr
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Identity and Access Management Tools [PDF]

International Journal of Trend in Scientific Research and Development, 2019
Identity and access management is a vital information security control for organizations to minimize the insider threats and advanced persistent threats that are caused by mismanaged user's identities and access control on sensitive business applications.
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Enhancing Federated Data Trading via Trustworthy Identity and Access Management Framework

Journal of Cybersecurity and Privacy
Trustworthy Identity and Access Management (IAM) is a foundational requirement for federated data trading platforms, yet existing solutions often rely on centralized Identity Providers (IdPs), lack cross-border interoperability, and offer limited support
Kyriakos Stefanidis, Vasilis Bekos, Dimitris Karadimas   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Mastering Advanced Azure AD: Cutting-Edge Techniques for Enterprise Identity Management [PDF]

, 2021
In an era where digital transformation and cloud adoption are reshaping business operations, effective identity management has become a critical cornerstone for organizational security and efficiency.
Sipho, Nkosi, Thandeka, Mthembu
core