Results 91 to 100 of about 18,601 (241)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Smart Contract Federated Identity Management without Third Party Authentication Services
, 2019 Federated identity management enables users to access multiple systems using a single login credential. However, to achieve this a complex privacy compromising authentication has to occur between the user, relying party (RP) (e.g., abusiness), and a ...
Dray, Jim, Mell, Peter, Shook, James
core
The success of any technology is not only dependent on the number of good reviews or great revenues, but also on the factors that can help one comprehend the level of acceptance that can be expected from any technology.
Wald, Mike, Alotaibi, Sara Jeza
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Benefits of Identity and Access Management
, 2013 Cílem této práce je definovat a ověřit přínosy Identity a Access managementu ve firmách a institucích. Práce nejdříve definuje obecné pojetí Identity a Access managementu. Následuje popis charakteristických vlastností a hodnocení jejich přínosu. Poslední
Strachota, Marek
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Mediated IBC-Based Management System of Identity and Access in Cloud Computing
Tikrit Journal of Engineering Sciences, 2014 Sufyan T. Farajaa, Sameeh A. Jassimab, K Kashif Kifayatb
doaj
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Enhancing Web Security and Performance with Hybrid Stateless Authentication
Journal of Applied Informatics and ComputingEnsuring operational integrity across industries and protecting sensitive data require strong authentication systems. This paper presents a novel hybrid stateless authentication method that integrates binary payloads, token specifications, and database ...
Benedictus Mario +2 more
doaj +1 more source