Results 131 to 140 of about 179,881 (285)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

How shared suffering bonded Britons witnessing the Queen’s funeral

open access: yesScientific Reports
Previous research suggests that sharing emotionally intense experiences with others, for example by undergoing dysphoric collective rituals together, can lead to “identity fusion,” a visceral feeling of oneness that predicts group cohesion and self ...
Claire White   +9 more
doaj   +1 more source

Construction of continuous $g$-frames and continuous fusion frames [PDF]

open access: yesSahand Communications in Mathematical Analysis, 2016
A generalization of the known results in fusion frames and $g$-frames theory to continuous fusion frames which defined by M. H. Faroughi and R. Ahmadi, is presented in this study. Continuous resolution of the identity (CRI) is introduced, a new family of
Mahdiyeh Khayyami, Akbar Nazari
doaj  

Trauma Bonding and Identity fusion

open access: yes
This paper examines why trauma bonds form selectively with some individuals and not others, even when multiple relationships involve emotional, psychological, or relational harm. Drawing on a lived experience and established psychological theory, it argues that trauma bonding emerges when narcissistic behaviours intersect with identity fusion ...
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The Role of Identity Fusion in Violent Extremism

open access: yes
Research spanning the globe including samples of current terrorists, former terrorists, individuals at risk of radicalization, and combatants against terrorism has shown that identity fusion – that is, a visceral feeling of commitment to a group, leader, or set of convictions – propels individuals to engage in extreme behaviors on behalf ...
Gómez, Ángel   +3 more
openaire   +3 more sources

Shared suffering predicts prosocial commitment among Turkish earthquake survivors

open access: yesScientific Reports
Previous research suggests that the perception of shared emotion associated with personally transformative events can foster a strong form of social bonding known as ‘identity fusion’, which motivates pro-group action.
Sevgi Demiroglu   +5 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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