Results 131 to 140 of about 37,577 (242)

Real‐World Validation of the Clinical Distinctiveness of IDH‐Mutant Glioblastoma in the SEER Transition Era: A Population‐Based Study Integrating Machine Learning

open access: yesBrain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Introduction The 2021 WHO classification reclassified “IDH‐mutant glioblastoma (GBM)” as “Astrocytoma, IDH‐mutant, grade 4.” This study aims to provide real‐world validation of this reclassification using the specific ICD‐O‐3 code (9445/3) from the Surveillance, Epidemiology, and End Results (SEER) “Transition Era” (2018–2022) and develop a ...
Dewei Du   +5 more
wiley   +1 more source

Association of CDKN2A/B and MTAP deletions in adult-type diffuse gliomas. [PDF]

open access: yesJ Neuropathol Exp Neurol
Ebner BA   +7 more
europepmc   +1 more source

Microbiota–Neuroinflammation Crosstalk in Primary Brain Tumors: Focus on Glioblastoma

open access: yesBrain and Behavior, Volume 16, Issue 8, August 2026.
Microbiota–neuroinflammation crosstalk in GBM. The schematic summarizes how gut microbiota and microbiota‐derived signals may influence GBM biology through gut–brain signaling, microbial metabolites, systemic immune modulation, BBB‐related pathways, tumor‐associated microbial signals, and immune‐metabolic changes within the GBM microenvironment.
Tareq Nayef AlRamadneh   +8 more
wiley   +1 more source

Deep Learning‐Based Multimodal Fusion of Whole‐Slide Images and RNA Sequencing Identifies Survival‐Relevant Glioblastoma Clusters

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Glioblastoma is profoundly heterogeneous, and single‐modality analyses often miss prognostically relevant structure. We introduce a transparent, end‐to‐end workflow that fuses available whole‐slide histology and RNA‐seq to discover clinically meaningful glioblastoma subgroups using an unsupervised learning model after feature extraction ...
Amin Zadeh Shirazi, Guillermo A. Gomez
wiley   +1 more source

Mass Spectrometry in Chiral Analysis and Synthesis

open access: yesChirality, Volume 38, Issue 8, August 2026.
Chiral molecules have the same mass, yet there are MS approaches that can distinguish chiral molecules. MS‐based chiral chemistry matters in fundamental physical experiments, industrial applications, and clinical analysis. ABSTRACT Mass spectrometry (MS) has a role to play in chiral chemistry, in part through methods based on microdroplets and non ...
Brison A. Shira   +2 more
wiley   +1 more source

DNA copy number patterns reveal prognostic markers and elucidate mechanisms of evolution in IDH-mutant astrocytoma. [PDF]

open access: yesNeuro Oncol
Drucker KL   +19 more
europepmc   +1 more source

Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei   +5 more
wiley   +1 more source

Current and emerging therapies in IDH-mutant glioma. [PDF]

open access: yesNeurotherapeutics
Nakhate V, Youssef G, Wen PY.
europepmc   +1 more source

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