Effect of Ambient Temperature on Intradialytic Hypotension in Hemodialysis Patients: A Retrospective Cohort Study. [PDF]
He Y, Qian Y, Xu Q, Sheng X, Zhang N.
europepmc +1 more source
ABSTRACT Introduction The 2021 WHO classification reclassified “IDH‐mutant glioblastoma (GBM)” as “Astrocytoma, IDH‐mutant, grade 4.” This study aims to provide real‐world validation of this reclassification using the specific ICD‐O‐3 code (9445/3) from the Surveillance, Epidemiology, and End Results (SEER) “Transition Era” (2018–2022) and develop a ...
Dewei Du +5 more
wiley +1 more source
Association of CDKN2A/B and MTAP deletions in adult-type diffuse gliomas. [PDF]
Ebner BA +7 more
europepmc +1 more source
Microbiota–Neuroinflammation Crosstalk in Primary Brain Tumors: Focus on Glioblastoma
Microbiota–neuroinflammation crosstalk in GBM. The schematic summarizes how gut microbiota and microbiota‐derived signals may influence GBM biology through gut–brain signaling, microbial metabolites, systemic immune modulation, BBB‐related pathways, tumor‐associated microbial signals, and immune‐metabolic changes within the GBM microenvironment.
Tareq Nayef AlRamadneh +8 more
wiley +1 more source
Diastolic Morning Surge Improves Risk Stratification for Subclinical Left Ventricular Diastolic Dysfunction in Ambulatory-Defined Isolated Diastolic Hypertension. [PDF]
Cosgun A, Oren H.
europepmc +1 more source
ABSTRACT Glioblastoma is profoundly heterogeneous, and single‐modality analyses often miss prognostically relevant structure. We introduce a transparent, end‐to‐end workflow that fuses available whole‐slide histology and RNA‐seq to discover clinically meaningful glioblastoma subgroups using an unsupervised learning model after feature extraction ...
Amin Zadeh Shirazi, Guillermo A. Gomez
wiley +1 more source
Mass Spectrometry in Chiral Analysis and Synthesis
Chiral molecules have the same mass, yet there are MS approaches that can distinguish chiral molecules. MS‐based chiral chemistry matters in fundamental physical experiments, industrial applications, and clinical analysis. ABSTRACT Mass spectrometry (MS) has a role to play in chiral chemistry, in part through methods based on microdroplets and non ...
Brison A. Shira +2 more
wiley +1 more source
DNA copy number patterns reveal prognostic markers and elucidate mechanisms of evolution in IDH-mutant astrocytoma. [PDF]
Drucker KL +19 more
europepmc +1 more source
Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei +5 more
wiley +1 more source
Current and emerging therapies in IDH-mutant glioma. [PDF]
Nakhate V, Youssef G, Wen PY.
europepmc +1 more source

