Results 151 to 160 of about 37,577 (242)

Metabolic Regulation of Macrophages in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang, Yu Zhang, Jiali Min, Jiahui Yang, Yuchen Li, Hao Zhang, Shanshan Liu   +6 more
wiley   +1 more source

<i>DLG2</i>-<i>DLG4</i> Expression Is Associated with Improved Survival and a Synaptic Gene Signature in Lower-Grade Glioma. [PDF]

Cancers (Basel)
Gaia F, Dal-Pizzol HR, Malafaia O, Roesler R, Isolan GR.   +4 more
europepmc   +1 more source

Glucose Transporter 1 in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai, Zhihao Chen, Yuping Zhu, Weidong Han   +3 more
wiley   +1 more source

Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy

MedComm, Volume 7, Issue 8, August 2026.
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge, Dong Han, Jing Wang, Xinyu Dai, Chen Ma, Feihong Chen   +5 more
wiley   +1 more source

The value of pleth variability index in predicting hypotension during maintenance hemodialysis: a prospective observational multicenter study (PVi-HD study). [PDF]

BMC Nephrol
Li J, Xu Q, Li F, Yang T, Gao C, Li Y, Zhou J, Cao Y, Tong C, Lu W, Wu Y.   +10 more
europepmc   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

PROTEOMICS, Volume 26, Issue 8, Page 29-40, August 2026.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan, Clinton J. Bradfield, Sandhini Saha, Sung Hwan Yoon, Iain D. C. Fraser, Aleksandra Nita‐Lazar   +5 more
wiley   +1 more source

Subtypes of Hypertension 2 to 7 Years After First Pregnancy. [PDF]

Hypertension
Brubaker LH, Catov JM, Bairey Merz CN, Barnes S, Barone Gibbs B, Booker W, Chung JH, Greenland P, Grobman WA, Khan SS, Lane A, Levine LD, McNeil RB, Miller EC, Muldoon MF, Ray M, Saade GR, Scifres CM, Silver RM, Simhan H, Yee LM, Hauspurg A.   +21 more
europepmc   +1 more source

Chronotherapy in Hematological Malignancies: Evaluating the Rationale and Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Hematological malignancies remain one of the leading causes of morbidity and mortality despite advances in targeted therapies, immunotherapy, and stem cell transplantation. Emerging evidence indicates that treatment efficacy and toxicity depend not only on the choice of therapy but also on its timing relative to the patient's internal ...
Andrej Belančić, Marko Skelin, Yun Wah Lam, Almir Fajkić, Bruna Perkov‐Stipičin, Rossana Roncato, Ivan Krečak, Marko Lucijanić   +7 more
wiley   +1 more source

Recurrent IDH-mutant astrocytoma WHO grade 4 diagnosed during pregnancy: case report with literature review. [PDF]

Front Oncol
Tleubergenov MA, Bakbayeva A, Zhamoldin DK, Doskaliyev A, Urazova UM, Tolepbergenova AD, Nurpeisov AZ, Takenov ZT, Akshulakov S.   +8 more
europepmc   +1 more source

South African Herbal Teas and Diabetes‐Mediated Mitochondrial Dysfunction: Emerging Evidence and Mechanistic Insights

Journal of Food Science, Volume 91, Issue 8, August 2026.
ABSTRACT Type 2 diabetes mellitus (T2DM) is a central component of the metabolic syndrome (MetS) and is associated with underlying mitochondrial dysfunction. Disruption of mitochondrial homeostasis impairs cellular energy metabolism and contributes to the overproduction of reactive oxygen species (ROS), leading to oxidative stress, chronic inflammation,
Shanika Reddy, Naeem Sheik Abdul, Taskeen Fathima Docrat, Jeanine Marnewick   +3 more
wiley   +1 more source