Gliomas with succinate dehydrogenase deficiency: A case series and brief review of the literature of oncometabolite-driven gliomagenesis. [PDF]
Gray MT +11 more
europepmc +1 more source
COVID‐19 Mortality in Swedish Intensive Care Units: A Multicenter Survival Analysis
ABSTRACT Background Mortality among critically ill COVID‐19 patients has varied globally. In Sweden, geographic differences in mortality have also been observed. The current study aimed to determine whether mortality differences persist after adjusting for differences in case‐mix, and to identify potential independent factors contributing to regional ...
Gustaf Forsberg +10 more
wiley +1 more source
The association of anxiety, depression, sleep quality and intradialytic hypotension in hemodialysis patients: a cross-sectional study. [PDF]
Jiang X +8 more
europepmc +1 more source
Immunohistochemistry as a tool for identifying EGFR amplification in CNS tumors
EGFR gene amplification constitutes a diagnostic hallmark for glioblastoma, IDH‐wildtype (GB, IDH‐WT). Herein, we demonstrated that EGFR IHC is a highly specific and sensitive biomarker for identifying EGFR amplification and should be part of the neuropathologist's routine panel of antibodies.
Arnault Tauziède‐Espariat +12 more
wiley +1 more source
Comparison between molecular and histological IDH-wild-type glioblastoma and extensive subgroup analysis of IDH-wild-type astrocytic tumors without genomic glioblastoma-defining alterations. [PDF]
Seifert AM +11 more
europepmc +1 more source
Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib
Summary: Isocitrate dehydrogenase (IDH)-mutant gliomas have distinctive metabolic and biological traits that potentially render them susceptible to targeted treatments.
Taranjit S. Gujral +24 more
core +1 more source
This integrated high‐resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34‐mutant expands the spectrum of associated genetic changes and underscores the presence of universal TP53 abnormalities at copy number, sequence, and protein expression level, with frequent yet largely unrecognized TP53 copy‐neutral loss of ...
Jorge A. Trejo‐Lopez +28 more
wiley +1 more source
Contemporary practice patterns in IDH-mutant glioma management: a multidisciplinary multi-institutional survey. [PDF]
Lanman TA +10 more
europepmc +1 more source
Comparative proteomics analysis of root and nodule mitochondria of soybean
Abstract Legumes perform symbiotic nitrogen fixation through rhizobial bacteroids housed in specialised root nodules. The biochemical process is energy‐intensive and consumes a huge carbon source to generate sufficient reducing power. To maintain the symbiosis, malate is supplied by legume nodules to bacteroids as their major carbon and energy source ...
Wai‐Ching Sin +4 more
wiley +1 more source
Right Frontal Isocitrate Dehydrogenase (IDH)-Mutant WHO Grade 3 Oligodendroglioma Presenting With Morning Headache and Gait Imbalance. [PDF]
Metwaly L.
europepmc +1 more source

