Results 161 to 170 of about 37,577 (242)

Unveiling the AcSirt2‐FOXO‐Mitophagy Axis: Insights Into Mitochondrial Quality Control and Delayed Aging in Apis cerana

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
Age‐related downregulation of AcSirt2 impairs mitochondrial homeostasis in old bees. AcSirt2‐mediated deacetylation of FOXO enhances transcriptional activity, upregulating antioxidant enzymes (SOD, CAT) and promoting PINK1/Parkin‐mediated mitophagy. This pathway facilitates autophagosome formation and clearance of damaged mitochondria, reducing ROS ...
Qiang Ma   +8 more
wiley   +1 more source

Exploring the role of advanced MRI in understanding glioblastoma biology: A scoping review protocol. [PDF]

open access: yesMethodsX
Brown-Miles J   +5 more
europepmc   +1 more source

Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment

open access: yesImmunology &Cell Biology, Volume 104, Issue 7, Page 711-728, August 2026.
Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari   +6 more
wiley   +1 more source

Low‐Profile Posterior Lumbar Fusion Combined With Proximal Interlaminar Coflex Dynamic Fixation for Lumbar Degenerative Diseases: A Comparative Study

open access: yesOrthopaedic Surgery, Volume 18, Issue 8, Page 1753-1767, August 2026.
Low‐profile topping‐off surgery, combining cortical bone trajectory screws with pedicle screws and Coflex stabilization, achieved comparable clinical outcomes to traditional topping‐off, with reduced incision length, blood loss, and drainage. This technique offers a less invasive approach and faster recovery for patients with lumbar degenerative ...
Kuan Li   +10 more
wiley   +1 more source

IDH1 Mutations Are Associated with Favorable Outcomes in Prostate Cancer. [PDF]

open access: yesEur Urol
Cavka L   +25 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy