Results 191 to 200 of about 58,205 (308)

Zinc Finger MYND-Type Containing 8 (ZMYND8) Is Epigenetically Regulated in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma to Promote Radioresistance [PDF]

, 2023
Stephen V. Carney, Kaushik Banerjee, Anzar Mujeeb, Brandon Zhu, Santiago Haase, María L. Varela, Padma Kadiyala, Claire E. Tronrud, Ziwen Zhu, Devarshi Mukherji, Preethi Gorla, Yilun Sun, Rebecca Tagett, Felipe J. Núñez, Maowu Luo, Weibo Luo, Mats Ljungman, Yayuan Liu, Ziyun Xia, Anna Schwendeman, Tingting Qin, Maureen A. Sartor, J Costello, Daniel P. Cahill, Pedro R. Löwenstein, María G. Castro   +25 more
openalex   +1 more source

Metformin Downregulates the STAT Pathway and Reduces Bone Marrow Fibrosis in Primary Myelofibrosis Patients: Final Results of the Phase II FIBROMET Trial

Hematological Oncology, Volume 44, Issue 1, January 2026.
ABSTRACT Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by the activation of the JAK‐STAT pathway. Previous evidence showed that metformin might be a possible therapeutic option for treating JAK2‐mediated myeloproliferative neoplasms.
Paula de Melo Campos, Kátia Borgia Barbosa Pagnano, Fernanda Soares Niemann, Rubia Isler Mancuso, Fernanda Isabel Della Via, Ada Congrains, Juan Luiz Coelho‐Silva, Ângela Condotta Tinoco, Guilherme Rossi Assis‐Mendonça, Leandro Luiz Lopes de Freitas, Fabiola Traina, Sara T. Olalla Saad   +11 more
wiley   +1 more source

Diagnostic and prognostic value of IDH1 mutation in gliomas

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To discuss the significance of IDH1 mutation for diagnosis and prognosis of gliomas through detecting of IDH1 mutation in supratentorial glioma cells.
Yan⁃wu YANG, Fei XIE, Jun⁃jia TANG, Shuang LIU, Xiang WANG, Yan⁃hui LIU, Qing MAO   +6 more
doaj  

Data from Loss of FBXW7 Correlates with Increased IDH1 Expression in Glioma and Enhances IDH1-Mutant Cancer Cell Sensitivity to Radiation

, 2023
Zhuo Yang, Nan Hu, Weiwei Wang, Weihua Hu, Shaolong Zhou, Jianxiang Shi, Minghe Li, Jing Zhou, Chao Chen, Xuyang Zhang, Ruyi Yang, Xudong Fu, Xinjun Wang   +12 more
openalex   +1 more source

Supplementary Table S2 from Zinc Finger MYND-Type Containing 8 (ZMYND8) Is Epigenetically Regulated in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma to Promote Radioresistance [PDF]

, 2023
Stephen V. Carney, Kaushik Banerjee, Anzar Mujeeb, Brandon Zhu, Santiago Haase, María L. Varela, Padma Kadiyala, Claire E. Tronrud, Ziwen Zhu, Devarshi Mukherji, Preethi Gorla, Yilun Sun, Rebecca Tagett, Felipe J. Núñez, Maowu Luo, Weibo Luo, Mats Ljungman, Yayuan Liu, Ziyun Xia, Anna Schwendeman, Tingting Qin, Maureen A. Sartor, J Costello, Daniel P. Cahill, Pedro R. Löwenstein, María G. Castro   +25 more
openalex   +1 more source

IDH1 NP_005887.2:p.R132C [PDF]

, 2020
openaire   +1 more source

IDH1 NP_005887.2:p.R132S [PDF]

, 2020
openaire   +1 more source

High‐Throughput 3D Glioblastoma Model in Glycosaminoglycan Hydrogels for Personalized Therapeutic Screening

Macromolecular Bioscience, Volume 26, Issue 1, January 2026.
Kaur–Trautmann et al. present a high‐throughput, chemically defined 3D glioblastoma model based on glycosaminoglycan hydrogels that allow orthogonal control of stiffness, adhesion, and degradability while standardizing soluble‐factor presentation. The platform supports automated imaging and transcriptomic profiling, enabling patient‐specific drug ...
Rajvinder Kaur Trautmann, Nicholas Dennison, Kathleen McCortney, Solveig Klier, Mehmet Ilyas Cosacak, Carsten Werner, Goktug Akyoldas, Craig M. Horbinski, Uwe Freudenberg, Caghan Kizil   +9 more
wiley   +1 more source

Isocitrate dehydrogenase 1 mutations drive downregulation of IL1R1 and dysregulated inflammatory response in acute myeloid leukemia. [PDF]

Blood Cancer J
Steinhäuser S, Beder T, Hübner E, Feuereisel DS, Jebens J, Wolgast N, Karaca MB, Richter K, Hedemann N, Steer B, Denker M, Bendig S, Brüggemann M, Silva P, Fransecky L, Neumann M, Stölzel F, Hartmann AM, Gemoll T, Bastian L, Baldus CD, Lipinski S.   +21 more
europepmc   +1 more source

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21 [PDF]

, 2018
Rubin, Joshua B.
core   +1 more source