Results 211 to 220 of about 58,205 (308)

Bridging the Gap: How Organ‐on‐a‐Chip Technology Facilitates the Battle against Glioma

Small Science, Volume 6, Issue 1, January 2026.
This review critically evaluates current state‐of‐the‐art in vitro glioma models especially glioma‐on‐a‐chip models based on readout capability, performance, and physiological relevance. It summarizes the key parameters and proposes a practical framework to guide researchers in selecting the most suitable preclinical models for glioma studies.
Su Liu, Zhenyu Gong, Dairan Zhou, Vanesa Ayala‐Nunez, Tao Xu, Peter Wick   +5 more
wiley   +1 more source

Exploring and Validating the Molecular Mechanisms Linking Fatty Acid Metabolism and Sarcopenia

IET Systems Biology, Volume 20, Issue 1, January/December 2026.
This study provides reference for fatty acid metabolism related potential candidate genes for sarcopenia and initially creates an effective machine learning models for further investigating the direction of the mechanism level. ABSTRACT Sarcopenia is an ageing‐related disease characterised primarily by skeletal muscle functional decline.
Ruopeng Yang, Shan Gu, Yang Li, Ping Xia
wiley   +1 more source

Contemporary Precision Stratification and Prognostic Features of Primary Gliomas in a Southern Chinese Population. [PDF]

Research (Wash D C)
Qu S, Ye Z, Pan Q, Xu H, Li H, Wang J, Zhang X, Ainiwan Y, Wang L, Yi G, Lin J, Li Z, Zheng X, Xie T, Huang Y, Liu T, Zhang X, Qi S, Huang G.   +18 more
europepmc   +1 more source

Table S1 from The Epigenetic Evolution of Glioma Is Determined by the <i>IDH1</i> Mutation Status and Treatment Regimen

Tathiane M. Malta, Thaís S. Sabedot, Natalia S. Morosini, Indrani Datta, Luciano Garofano, Wies Vallentgoed, Frederick S. Varn, Kenneth Aldape, Fulvio D’Angelo, Spyridon Bakas, Jill S. Barnholtz‐Sloan, Hui Gan, Mohammad Hasanain, Ann‐Christin Hau, Kevin C. Johnson, Simona Cazacu, Ana C. deCarvalho, Mustafa Khasraw, Emre Kocakavuk, Mathilde C.M. Kouwenhoven, Simona Migliozzi, Simone P. Niclou, Johanna M. Niers, D. Ryan Ormond, Sun Ha Paek, Guido Reifenberger, Peter A. Sillevis Smitt, Marion Smits, Lucy F. Stead, Martin J. van den Bent, Erwin G. Van Meir, Annemiek Walenkamp, Tobias Weiß, Michael Weller, Bart A. Westerman, Bauke Ylstra, Pieter Wesseling, Anna Lasorella, Pim J. French, Laila Poisson, Adelheid Wöehrer, Allison Lowman, Ana C. deCarvalho, Ana Valeria Castro, Andrea Transou, Andrew Brodbelt, Ann‐Christin Hau, Anna Lasorella, Anna Golebiewska, Annemiek Walenkamp, Annette M. Molinaro, Antonio Iavarone, Azzam Ismail, Bart A. Westerman, Bauke Ylstra, Christoph Bock, D. Ryan Ormond, Daniel J. Brat, Emre Kocakavuk, Erwin G. Van Meir, Floris P Barthel, Frederick S. Varn, Fulvio D’Angelo, Gaetano Finocchiaro, Hui Gan, Gelareh Zadeh, Guido Reifenberger, Ho Keu ngNg, Hoon Kim, Houtan Noushmehr, Hrvoje Miletić, Hui Gan, Indrani Datta, Jack Rock, James M. Snyder, Jason T. Huse, Jennifer Connelly, Jill S. Barnholtz‐Sloan, Johanna M. Niers, John DeGroot, Kadir C. Akdemir, Kasthuri Kannan, Keith L. Ligon, Kenneth Aldape, Ketan R. Bulsara, Kevin C. Johnson, Kristin D Alfaro, Laila Poisson, Luciano Garofano, Lucy F. Stead, MacLean P. Nasrallah, Marion Smits, Martin J. van den Bent, Mathilde C.M. Kouwenhoven, Michael Weller, Mohammad Hasanain, Mustafa Khasraw, Peter V. Gould, Peter A. Sillevis Smitt, Peter S. LaViolette   +99 more
openalex   +1 more source

Autocrine BMP4 Signaling Enhances Tumor Aggressiveness via Promoting Wnt/β-Catenin Signaling in IDH1-mutant Gliomas

, 2019
Yiqiang Zhou, Yang Liu, Junwen Zhang, Di Yu, Aiguo Li, Hua Song, Wei Zhang, Dionne Davis, Mark R. Gilbert, Fusheng Liu, Chunzhang Yang   +10 more
openalex   +1 more source

Supplemental Information from Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells

, 2023
Mahsa Zarei, Shruti Lal, Seth J. Parker, Avinoam Nevler, Ali Vaziri‐Gohar, Katerina Dukleska, Nicole C. Mambelli‐Lisboa, Cynthia Moffat, Fernando F. Blanco, Saswati N. Chand, Masaya Jimbo, Joseph A. Cozzitorto, Wei Jiang, Charles J. Yeo, Eric Londin, Erin L. Seifert, Christian M. Metallo, Jonathan R. Brody, Jordan M. Winter   +18 more
openalex   +1 more source

Spatial Transcriptomic Characteristics of the Aging Human Ovary

Aging Cell, Volume 25, Issue 1, January 2026.
Troughing constructing a comprehensive spatiotemporal aging atlas on young and aged human ovaries, we revealed distinct cell types, cellular interactions, and aging‐associated gene expression changes due to aging. Specially, we detected an increase in DLK1:NOTCH3 expression which may contribute to the dysregulation of ovarian functions.
Meiling Zhang, Fanghao Guo, Qing Zhang, Qianhui Hu, Di Sun, Yongjian Ma, Yanquan Li, Mengxi Guo, Haixia Ding, Ying Guo, Baicai Yang, Songmao Li, Ningxia Sun, Yuxuan Zheng, Wen Li   +14 more
wiley   +1 more source

Blast Clearance Dynamics and Time to Response Across <i>IDH1-</i> and <i>IDH2</i>-Mutated AML. [PDF]

EJHaem
Najeeb MS, Alkabbani O, He R, Jevremovic D, Greipp PT, Matin A, Hefazi M, Mangaonkar A, Patnaik M, Gangat N, Hogan WJ, Litzow MR, Yi CYA, Foran JM, Alkhateeb HB, Shah M, Begna K, Kewan T, Saliba AN, Al-Kali A.   +19 more
europepmc   +1 more source

IDH1 mutation is detectable in plasma cell-free DNA and is associated with survival outcome in glioma patients [PDF]

Stefania Crucitta, Francesco Pasqualetti, Alessandra Gonnelli, Martina Ruglioni, Giovanna Irene Luculli, M. Cantarella, Valerio Ortenzi, Cristian Scatena, Fabiola Paiar, Antonio Giuseppe Naccarato, Romano Danesi, Marzia Del Re   +11 more
openalex   +1 more source

Comparability of external and internal control patients for the prospective randomized HOVON‐103 trial in older AML patients

British Journal of Haematology, Volume 208, Issue 1, Page 179-188, January 2026.
Summary Real‐world data (RWD) previously contributed to post‐marketing regulatory decision‐making, but are currently also considered as external controls to single‐arm trials. The use of RWD control data may be compromised by methodological issues, urging validation of RWD control cohorts.
Sjoerd J. F. Hermans, Jurjen Versluis, Erik D. van Werkhoven, Yvette van Norden, Jeroen J. W. M. Janssen, Gerwin A. Huls, Thomas Pabst, Dimitri A. Breems, Elizabeth Berkx, Avinash G. Dinmohamed, Peter C. Huijgens, Eric Sträng, Jesús María Hernández Rivas, Marta Sobas, Rosa Ayala Diaz, Joaquin Martinez Lopez, Klaus H. Metzeler, Torsten Haferlach, Christian Thiede, Carin A. Uyl‐de Groot, Lars Bullinger, Bob Löwenberg, Gert J. Ossenkoppele, Francesco Pignatti, Jan J. Cornelissen   +24 more
wiley   +1 more source