Results 221 to 230 of about 63,359 (335)

Expressão de CXCR7 e CXCR4 em em astrocitomas iniltrativos em relação ao tecido cerebral não neoplásico e sua interação com HIF1alfa e IDH1 [PDF]

, 2013
André de Macedo Bianco
openalex   +1 more source

Haptoglobin and Glutamine Synthetase May Biomark Cachexia Induced by Antiacute Myeloid Leukaemia Chemotherapy

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.
ABSTRACT Background Anticancer chemotherapy is an underappreciated contributor to cancer cachexia, an often‐irreversible body‐wasting condition that causes 20%–30% of cancer‐related deaths. An obstacle to predicting, monitoring and understanding the mechanisms underlying chemotherapy cachexia is that each cancer (and subtype) is assigned different ...
Dean G. Campelj, Cara A. Timpani, Guinevere Spiesberger, Luke E. Formosa, Joel R. Steele, Haijian Zhang, Ralf B. Schittenhelm, Lewis Leow, Craig A. Goodman, Emma Rybalka   +9 more
wiley   +1 more source

Faculty Opinions recommendation of Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.

, 2011
Robert Abraham
openalex   +2 more sources

METABOLIC IMAGING BIOMARKERS FOR MUTANT IDH1 GLIOMAS [PDF]

, 2014
Sabrina M. Ronen, José Luis Izquierdo-García, Myriam M. Chaumeil, Larry Cai, Joanna J. Phillips, Russell O. Pieper   +5 more
openalex   +1 more source

Diagnostic Accuracy of 1H‐MRS Using PRESS and MEGA‐PRESS Techniques in the Preoperative Grading of Patients With Gliomas

Journal of Magnetic Resonance Imaging, Volume 61, Issue 6, Page 2480-2488, June 2025.
Background Edited MRS technique such as MEshcher‐GArwood Point RESolved Spectroscopy (MEGA‐PRESS) can determine isocitrate dehydrogenase mutation (IDH) mutation status in patients with gliomas but its accuracy in assessing glioma grade has not yet been formally evaluated.
Maria L. Brun‐Vergara, Gerd Melkus, Santanu Chakraborty, Nader Zakhari, Carlos Torres, Fahad AlKherayf, Leya Ghantous, Rebecca Thornhill, John Woulfe, Gerard H. Jansen, Thanh B. Nguyen   +10 more
wiley   +1 more source

Can Diffusion Tensor Imaging Noninvasively Detect IDH1 Gene Mutations in Astrogliomas? A Retrospective Study of 112 Cases [PDF]

, 2014
Wenli Tan, Weiyuan Huang, Bo Yin, Ji Xiong, Jinsong Wu, Daoying Geng   +5 more
openalex   +1 more source

Genomic Profiling of Biliary Tract Cancers: Comprehensive Assessment of Anatomic and Geographic Heterogeneity, Co‐Alterations and Outcomes

Journal of Surgical Oncology, Volume 131, Issue 7, Page 1352-1361, June 2025.
ABSTRACT Background Biliary tract cancers (BTCs) represent distinct biological and genomic entities. Anatomic and geographic heterogeneity in genomic profiling of BTC subtypes, genomic co‐alterations, and their impact on long‐term outcomes are not well defined.
Diamantis I. Tsilimigras, Hunter Stecko, Dimitrios Moris, Timothy M. Pawlik   +3 more
wiley   +1 more source

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

, 2012
Masato Sasaki, Christiane B. Knobbe‐Thomsen, Joshua Munger, Evan Lind, Dirk Brenner, Anne Brüstle, Isaac S. Harris, Roxanne Holmes, Andrew Wakeham, Jillian Haight, Annick You-Ten, Wanda Y. Li, Stefanie S. Schalm, Shinsan M. Su, Carl Virtanen, Guido Reifenberger, Pamela S. Ohashi, Dwayne L. Barber, María E. Figueroa, Ari Melnick, Juan Carlos Zúñiga‐Pflücker, Tak W. Mak   +21 more
openalex   +2 more sources

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity [PDF]

, 2014
Suganthi Chittaranjan, Susanna Chan, C. Paul Yang, Kevin Yang, Vincent Chen, Annie Moradian, Marlo Firme, Jungeun Song, Nancy E. Go, Michael Blough, Jennifer A. Chan, J. Gregory Cairncross, Sharon M. Gorski, Gregg B. Morin, Stephen Yip, Marco A. Marra   +15 more
openalex   +1 more source

Clinical Use of Comprehensive Genomic Profiling Tests in Intrahepatic Cholangiocarcinoma: A Single‐Center Retrospective Study

Liver International Communications, Volume 6, Issue 2, June 2025.
ABSTRACT The clinical utility of comprehensive genomic profiling (CGP) in intrahepatic cholangiocarcinoma (ICC) remains to be fully elucidated. This study analysed CGP test results and evaluated treatment outcomes with fibroblast growth factor receptor (FGFR) inhibitors in patients with ICC, aiming to assess their efficacy in cases with specific FGFR ...
Makiko Urabe, Takuo Yamai, Kenji Ikezawa, Kazuhiro Kozumi, Yugo Kai, Ryoji Takada, Kaori Mukai, Tasuku Nakabori, Hiroshi Wada, Naotoshi Sugimoto, Kazuyoshi Ohkawa   +10 more
wiley   +1 more source