Results 231 to 240 of about 63,359 (335)

IDH1 mutation is associated with seizures and protoplasmic subtype in patients with low‐grade gliomas [PDF]

, 2014
Simon V. Liubinas, Giovanna M. D’Abaco, Bradford A. Moffat, Michael Gonzales, Frank Feleppa, Cameron J. Nowell, Alexandra Gorelik, Katharine J. Drummond, Terence J. O’Brien, Andrew H. Kaye, Andrew Morokoff   +10 more
openalex   +1 more source

The Nasal–Brain Drug Delivery Route: Mechanisms and Applications to Central Nervous System Diseases

MedComm, Volume 6, Issue 6, June 2025.
Τhe BBB restricts CNS drug delivery. NBDD bypasses the BBB via olfactory/trigeminal routes, enabling CNS delivery of therapeutic (small molecules, biologics, nucleic acids) for neurodegenerative/psychiatric disorders and brain tumors using advanced NBDD delivery systems (e.g nanocarriers) to enhance targeting and bioavailability.
Yi Qiu, Shiyuan Huang, Li Peng, Li Yang, Guosong Zhang, Tao Liu, Fang Yan, Xi Peng   +7 more
wiley   +1 more source

IDH1 Mutations in Oligodendroglial Tumors: Comparative Analysis of Direct Sequencing, Pyrosequencing, Immunohistochemistry, Nested PCR and PNA‐Mediated Clamping PCR

, 2012
Dakeun Lee, Yeon‐Lim Suh, So Young Kang, Tae In Park, Ji Yun Jeong, Se Hoon Kim   +5 more
openalex   +2 more sources

Isocitrate Dehydrogenase 1 (IDH1) Mutation in Breast Adenocarcinoma Is Associated With Elevated Levels of Serum and Urine 2-Hydroxyglutarate [PDF]

, 2014
Amir T. Fathi, Hossein Sadrzadeh, Amy Comander, Michaela J. Higgins, Aditya Bardia, Ashley Perry, Meghan Burke, Regina Silver, Christina R. Matulis, Kimberly Straley, Katharine Yen, Sam Agresta, Hyeryun Kim, David P. Schenkein, Darrell R. Borger   +14 more
openalex   +1 more source

Isocitrate dehydrogenase-mutant astrocytoma in persons aged 55 years and older: Survival differences versus the young. [PDF]

J Neuropathol Exp Neurol
Siddiq Z, Gilani A, Ung TH, Kleinschmidt-DeMasters BK.   +3 more
europepmc   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy

Small Science, Volume 5, Issue 6, June 2025.
Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri, Rodolfo Villa, Ya‐Ping Shiau, Menghuan Tang, Kelsey Jane Racacho, Qiufang Zong, Saiful Islam Chowdhury, Tan Hua, Felipe Godinez, Andrew Birkeland, Tzu‐Yin Lin, Yuanpei Li   +11 more
wiley   +1 more source

Mutant IDH1 Is an Effective Immunotherapeutic Target for Glioma [PDF]

, 2014

openalex   +1 more source

Panoramic spatial enhanced resolution proteomics (PSERP) reveals tumor architecture and heterogeneity in gliomas. [PDF]

J Hematol Oncol
Xu Z, Wang Y, Xie T, Luo R, Ni HL, Xiang H, Tang S, Tan S, Fang R, Ran P, Zhang Q, Xu X, Tian S, He F, Yang W, Ding C.   +15 more
europepmc   +1 more source

The Ancient Drug Salicylate Indirectly Targets Fructose‐1,6‐Bisphosphatase to Suppress Liver Glucose Production in Diet‐Induced Obese Mice

Acta Physiologica, Volume 241, Issue 6, June 2025.
ABSTRACT Aims The benefit of salicylate in the treatment of diabetes has been recognized for over a century; however, challenging side effects have prevented widespread use. A better understanding of the relevant enzyme targets mediating its anti‐hyperglycaemic effect may lead to the development of novel therapies for diabetes.
Raid B. Nisr, Abdelmadjid Atrih, Erika J. Gutierrez Lara, Douglas Lamont, Katarzyna M. Luda, Rory J. McCrimmon, Kei Sakamoto, Graham Rena, Alison D. McNeilly   +8 more
wiley   +1 more source