Results 231 to 240 of about 58,205 (308)

STMO-13 PATHOLOGICAL EVALUATION AND ONCOLOGICAL OUTCOME OF FLAIRECTOMY IN PATIENTS WITH IDH1 WILD-TYPE GLIOBLASTOMA

, 2022
Seiichiro Hirono, Yusuke Kouchi, Takashi Kishimoto, Masayoshi Kobayashi, Tomoo Matsutani, Yasuo Iwadate   +5 more
openalex   +1 more source

Isocitrate dehydrogenase 1 (IDH1) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

cIMPACT‐NOW update 11: Proposal on adaptation of diagnostic criteria for IDH‐ and H3‐wildtype diffuse high‐grade gliomas and for posterior fossa ependymal tumors

Brain Pathology, Volume 36, Issue 1, January 2026.
Abstract The Consortium to Inform Molecular and Practical Approaches to Central Nervous System Tumor Taxonomy (cIMPACT‐NOW) updates provide guidelines for the diagnosis of central nervous system (CNS) tumors and suggestions for future World Health Organization (WHO) classification.
Pieter Wesseling, David Capper, Guido Reifenberger, Chitra Sarkar, Cynthia Hawkins, Arie Perry, Bette Kleinschmidt‐DeMasters, Takashi Komori, Werner Paulus, Vani Santosh, Martin van den Bent, Michael Weller, Stefan M. Pfister, Uri Tabori, Dominique Figarella‐Branger, Brent A. Orr, David N. Louis   +16 more
wiley   +1 more source

Integrating molecular profiling into glioma diagnosis: implications of the WHO-CNS5-2021 classification of adult-type diffuse gliomas in Colombian patients. [PDF]

Front Neurol
Echeverría O, Patiño-Aldana AF, Chinchilla AM, Contreras N, Peralta S, Caballero N, Tovar HV, Palacio JM, Uribe V, Mineo-Pachón M, Velandia F, Castillo WMR, Valero N, Silgado-Guzmán DF, Ondo-Mendez A, Fonseca-Mendoza DJ.   +15 more
europepmc   +1 more source

IDH1/2 Mutations in Cancer: Unifying Insights and Unlocking Therapeutic Potential for Chondrosarcoma [PDF]

Shriya Deshmukh, Ciara M. Kelly, Gabriel Tinoco   +2 more
openalex   +1 more source

NRF2 signalling in cytoprotection and metabolism

British Journal of Pharmacology, Volume 183, Issue 1, Page 101-114, January 2026.
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami, Yusuke Kusano, Keito Okazaki, Takaaki Akaike, Hozumi Motohashi   +4 more
wiley   +1 more source

PRDM16 expression is an independent prognostic factor in AML with the double-mutant NPM1/FLT3-ITD genotype. [PDF]

Ann Hematol
Stasik S, Eckardt JN, Röllig C, Baldus CD, Serve H, Müller-Tidow C, Schäfer-Eckart K, Kaufmann M, Krause SW, Hänel M, Neubauer A, Ehninger G, Platzbecker U, Bornhäuser M, Schetelig J, Middeke JM, Thiede C.   +16 more
europepmc   +1 more source

FGFR2 Fusions or Rearrangements in Young Intrahepatic and Perihilar Cholangiocarcinoma Patients: Key Genetic Insights From a Pan‐Asian Study

Hepatology Research, Volume 56, Issue 1, Page 78-88, January 2026.
FGFR2 Alterations in Young Adults with cholangiocarcinoma was common. Intrahepatic cholangiocarcinoma (ICC) is a rare liver cancer, typically seen in older adults. This study focused on younger patients across Asia, examining changes in the FGFR2 gene that may drive cancer growth.
Yuta Maruki, Yasushi Yatabe, Chiharu Mizoguchi, Kathleen Yasmin de Almeida, Aumkhae Sookprasert, Charuwan Akewanlop, Ming‐Huang Chen, Ekaphop Sirachainan, Dao Van Tu, Rozita Abdul Malik, Chaiyut Charoentum, Hwoei Fen Soo Hoo, Suhana Yusak, Tsung‐Hao Liu, Rangasamy Ramachandran, Patrapim Sunpaweravong, Pei Jye Voon, Najihah Abu Bakar, Junki Mizusawa, Hitomi Sumiyoshi Okuma, Kenichi Nakamura, Chigusa Morizane, Takuji Okusaka   +22 more
wiley   +1 more source

PARP inhibitor resistance in IDH1-mutant cancers due to loss of end protection factors, 53BP1 and REV7. [PDF]

NAR Cancer
Colón-Ríos DA, Dow J, Krysztofiak A, Liu Y, Rogers FA, Glazer PM.   +5 more
europepmc   +1 more source

IDH1(R132) Inhibitor IDH305 [PDF]

, 2020
openaire   +1 more source