Results 241 to 250 of about 63,359 (335)

Correlation of EGFR, IDH1 and PTEN status with the outcome of patients with recurrent glioblastoma treated in a phase II clinical trial with the EGFR-blocking monoclonal antibody cetuximab

, 2012
Shasha Lv, Erik Teugels, Jan Sadones, Sylvia De Brakeleer, Johnny Duerinck, Stephanie Du Four, Alex Michotte, Jacques De Grève, Bart Neyns   +8 more
openalex   +2 more sources

The NADP+-dependent IDH1 mutation and its relevance for glioblastoma patient survival [PDF]

, 2014
Cornelis J.F. Van Noorden
openalex   +1 more source

Disease characteristics and monitoring of IDH1/IDH2-mutated acute myeloid leukemia. [PDF]

Blood Cancer J
Dantec M, Dufossé M, Boudry A, Fournier E, Goursaud L, Lebon D, Bories C, Plantier I, Tricot S, Daniel A, Willaume A, Coiteux V, Berthon C, Marolleau JP, Preudhomme C, Duployez N, Fenwarth L.   +16 more
europepmc   +1 more source

FN1 Immunoregulation in Glioblastoma: Insights From Neutrophil‐Centric Studies

Cancer Science, Volume 116, Issue 6, Page 1758-1772, June 2025.
Blurb for ETOC Our study identifies a novel neutrophil‐related gene signature that enhances the prognostic prediction for glioblastoma patients. The research highlights FN1 as a central immune regulator associated with poor survival outcomes and heightened immune activity in glioblastoma, positioning it as a promising therapeutic target. We propose the
Xiangtian Meng, Xusen Yang, Junle Zhu, Huairui Chen, Chun Luo, Fenglin Zhang, Qin Zhang, Jingliang Ye   +7 more
wiley   +1 more source

Integrated genomic characterization of IDH1-mutant glioma malignant progression [PDF]

, 2015
Hanwen Bai, Akdes Serin Harmancı, E. Zeynep Erson‐Omay, Jie Li, Süleyman Coşkun, Matthias Simon, Boris Krischek, Koray Özduman, Sacit Bulent Omay, Eric A. Sorensen, Şevin Turcan, Mehmet Bakırcığlu, Geneive Carrión-Grant, Phillip B. Murray, Victoria Clark, A. Gulhan Ercan‐Sencicek, James Knight, Leman Sencar, Selin Altınok, Leon D. Kaulen, Burcu Gülez, Marco Timmer, Johannes Schramm, Ketu Mishra-Gorur, Octavian Henegariu, Jennifer Moliterno, Angeliki Louvi, Timothy A. Chan, Stacey Tannheimer, M. Necmettin Pamir, Alexander O. Vortmeyer, Kaya Bilgüvar, Katsuhito Yasuno, Murat Günel   +33 more
openalex   +1 more source

Machine learning-based identification of exosome-related biomarkers and drugs prediction in nasopharyngeal carcinoma. [PDF]

Discov Oncol
Wei Z, Wang G, Hu Y, Zhou C, Zhang Y, Shen Y, Wang Y.   +6 more
europepmc   +1 more source

VCP Promotes Cholangiocarcinoma Development by Mediating BAP1 Ubiquitination‐Dependent Degradation

Cancer Science, Volume 116, Issue 6, Page 1579-1591, June 2025.
It demonstrates the tumor‐suppressive roles of BAP1 in CCA: BAP1 significantly inhibits CCA cell proliferation and tumor progression. It identifies VCP as a key upstream regulator mediating BAP1 homeostasis: VCP binds to BAP1 and promotes the latter's ubiquitination degradation via the ubiquitin‐proteasome pathway.
Peiying Zhang, Xiangning Liu, Yue Liu, Hongdao Zhu, Churun Zheng, Qi Ling, Fangjie Yan, Qiaojun He, Hong Zhu, Tao Yuan, Bo Yang   +10 more
wiley   +1 more source

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21 [PDF]

, 2018
Rubin, Joshua B.
core   +1 more source

DNA Damage Repair in Glioblastoma: A Novel Approach to Combat Drug Resistance

Cell Proliferation, Volume 58, Issue 6, June 2025.
Glioblastoma (GBM) stem cells are useful model for in vitro drug characterisation. DNA repair mechanisms can contribute to cancer cell survival. Pt(IV) bearing Histone DeACetylase inhibitors enhances anticancer effects by disrupting DNA damage response. Poly ADP ribose polymerases inhibitors could adjuvate GBM treatment.
Ludovica Gaiaschi, Claudio Casali, Andrea Stabile, Sharon D'Amico, Mauro Ravera, Elisabetta Gabano, Andrea Galluzzo, Cristina Favaron, Federica Gola, Fabrizio De Luca, Serena Pellegatta, Maria Grazia Bottone   +11 more
wiley   +1 more source

Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines [PDF]

, 2015
Johnny Suijker, Jan Oosting, Annemarie Koornneef, Eduard A. Struys, Gajja S. Salomons, Frank G. Schaap, Cathelijn J. F. Waaijer, Pauline M. Wijers‐Koster, Inge H. Briaire‐de Bruijn, Lizette C. J. M. Haazen, Scott M. Riester, Amel Dudakovic, Erik H.J. Danen, Anne‐Marie Cleton‐Jansen, André J. van Wijnen, Judith V.M.G. Bovée   +15 more
openalex   +1 more source