Results 251 to 260 of about 58,205 (308)

Rare IDH hotspot mutations in dysembryoplastic neuroepithelial tumors expand the spectrum of IDH-altered CNS tumors. [PDF]

Acta Neuropathol
Raby M, Servant E, Dangouloff-Ros V, Lebre AS, Simboli GA, Saffroy R, Benichi S, Bourgeois M, Blauwblomme T, Onken J, Koch A, Schmid S, Chrétien F, Tauziède-Espariat A, Varlet P, Capper D, Métais A.   +16 more
europepmc   +1 more source

Epidemiology and characteristics of validated mixed phenotype acute leukaemia—A comprehensive nationwide Danish cohort study

British Journal of Haematology, Volume 208, Issue 1, Page 353-357, January 2026.
Lisa‐Maj Christensen, Daniel Tuyet Kristensen, Karen Dybkær, Kirsten Grønbæk, Tarec Christoffer El‐Galaly, Marianne Schmidt Ettrup, Jonas Faartoft Jensen, Hans Beier Ommen, Anne Louise Tølbøll Sørensen, Dennis Lund Hansen, Rasmus Froberg Brøndum, Marianne Tang Severinsen   +11 more
wiley   +1 more source

Multi‐Omics Evidence Based on Spatial Transcriptomics Data Reveals the Therapeutic Value of Copper Death Genes in Glioblastoma

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Background Cuprotosis is an emerging form of copper‐dependent programmed cell death, while low‐grade gliomas (LGGs) represent a common subtype of primary brain tumors. Methods Datasets from The Cancer Genome Atlas and TargetScan were utilized to identify cuprotosis‐related microRNAs (CRMs).
Zhaoliang Xue, Zhengfei Song, Lianjie Mo, Shuxu Yang, Qi Wang   +4 more
wiley   +1 more source

Unpredictable Evolution of Pilocytic Astrocytoma in Adults: A Case Series and Diagnostic Challenges. [PDF]

Am J Case Rep
Sincu A, Orasanu CI, Voda RI, Bosoteanu M, Enciu M, Vamesu S, Ghitoi SA, Deacu M.   +7 more
europepmc   +1 more source

Glutamine enhances endothelial cell survival and vasodilation by increasing glutathione to reduce oxidative stress

Physiological Reports, Volume 14, Issue 2, January 2026.
Abstract Cardiovascular disease is exacerbated by diabetes through hyperglycemia‐induced endothelial dysfunction, which arises from oxidative stress. Glutamine is postulated to decrease oxidative stress; however, its effect on endothelial dysfunction in hyperglycemia is unknown.
Marzyeh Kheradmand, Gurneet Sangha, Claire M. Sissons, Michael Sun, Xinyao Zhou, Lauren V. Smith, Meagan Bauer, Chengpeng Chen, Alisa Morss Clyne   +8 more
wiley   +1 more source

Single-cell multi-omics identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma. [PDF]

Nat Commun
Veo B, Wang D, DeSisto J, Pierce A, Brunt B, Bompada PC, Donson A, Goodspeed A, Smart K, Foreman N, Dahl N, Vibhakar R.   +11 more
europepmc   +1 more source

Intraventricular mass in a 49‐year‐old male

Brain Pathology, Volume 36, Issue 1, January 2026.
Connor R. Zuraski, Donald P. Pizzo, Jessica D. Schulte, Vanessa S. Goodwill   +3 more
wiley   +1 more source

Disruption of Mitochondrial Dynamics and Integrity Drives Divergent Metabolic Flexibility and Resilience in Podocytes

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
We investigated two models of mitochondrial dysfunction in podocytes, using two cell culture models: podocytes isolated from mice with Oma1 deletion (Oma1del) and mouse podocytes modified with an inducible knockdown of PHB2 (Phb2kd). OMA1 deficiency induced a glycolytic shift, enhanced glutamine anaplerosis, and sustained energy homeostasis after ...
Cem Özel, Katrin M. Reitmeier, Emilia Kieckhöfer, Khawla Abualia, Duc Nguyen‐Minh, Mahsa Matin, Henning Hagmann, Richard J. M. Coward, Sebastian Brähler, Philipp Antczak, Bernhard Schermer, Thomas Benzing, Patrick Giavalisco, Paul T. Brinkkoetter   +13 more
wiley   +1 more source

Ultrasensitive Detection of Rare Mutations via Amplifying-Cleaving-Enriching in Acute Myeloid Leukemia. [PDF]

Biomedicines
Zhuang X, Ma L, Yu L, Zhao Y, Zhang D, Li C, Liu C, Xiao Y, Chang Z, Li S, Chen C, Chen Y, Zhou G, Zhao ZJ, Guo Y.   +14 more
europepmc   +1 more source

Next-Generation Sequencing Reveals a Diagnostic and Prognostic Role of the <i>TP53</i> R273C Mutation in Lower-Grade, <i>IDH</i>-Mutant Astrocytomas. [PDF]

Int J Mol Sci
Navarro L, Megías J, Salazar-Saura I, Sánchez-Pardo M, Roselló-Sastre E, San-Miguel T.   +5 more
europepmc   +1 more source