Results 181 to 190 of about 57,146 (292)

Brivaracetam‐associated manic episode in a patient with bipolar disorder: A case report

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
A patient with Bipolar I disorder developed manic symptoms following the initiation of brivaracetam for focal epilepsy. Although brivaracetam is generally considered to have favorable psychiatric tolerability, this case highlights a potential risk of mood destabilization in patients with underlying bipolar disorder.
Mihoko Kawai   +2 more
wiley   +1 more source

Cerebrospinal fluid-specific oligoclonal bands in dogs with idiopathic epilepsy. [PDF]

open access: yesJ Vet Intern Med
Föhr J   +10 more
europepmc   +1 more source

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner   +6 more
wiley   +1 more source

A Multi‐Institutional Retrospective Study of 21 Dogs Having Undergone Hypofractionated Radiotherapy for Adrenal Tumours (2017–2024)

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 2, Page 229-239, June 2026.
ABSTRACT Radiation therapy (RT) has emerged as a promising non‐surgical approach for treating canine adrenal tumours. This multi‐institutional, retrospective study describes clinical outcomes for 21 dogs having been prescribed a course of hypofractionated image‐guided intensity‐modulated RT (IMRT) entailing delivery of 25–35 Gy total in 5 fractions ...
Yen‐Hao Erik Lai   +4 more
wiley   +1 more source

Reconstructing cerebral lymphatic clearance: an emerging target in the Alzheimer's disease therapeutic pipeline

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract Neurotoxic protein accumulation is widely recognized as a key feature of Alzheimer's disease (AD), and increasing evidence indicates that impaired brain clearance associated with dysfunction of the meningeal lymphatic and glymphatic may contribute to this process.
Jiheng Zhang   +8 more
wiley   +1 more source

Cerebral Cortex Morphometry and Relaxometry in Male Children With Fragile X Syndrome and Autism

open access: yesBrain and Behavior, Volume 16, Issue 5, May 2026.
In this study, regions of the cortex highlighted in shades of blue indicate children with fragile X syndrome have increased cortical thickness compared to children with autism spectrum disorder. ABSTRACT Purpose An estimated 30%–50% of male individuals with fragile X syndrome (FXS) meet criteria for autism spectrum disorder (ASD), indicating phenotypic
Jose M. Guerrero‐Gonzalez   +5 more
wiley   +1 more source

Mechanotransduction in the Brain: Soliton Theory, Piezo Receptors and MR Elastography in Headache Pathophysiology

open access: yesBrain and Behavior, Volume 16, Issue 5, May 2026.
ABSTRACT Purpose This narrative review aims to explore how incorporating mechanical and thermal dimensions can complement and extend the classical Hodgkin‐Huxley (HH) model to enrich the understanding of headache and pain pathophysiology. Method This review examines the integration of three distinct concepts with the HH model.
Joan Crespi   +5 more
wiley   +1 more source

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