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Monogenic idiopathic epilepsies
The Lancet Neurology, 2004Major advances have recently been made in our understanding of the genetic bases of monogenic inherited epilepsies. Direct molecular diagnosis is now possible in numerous inherited symptomatic epilepsies. Progress has also been spectacular with respect to several idiopathic epilepsies that are caused by mutations in genes encoding subunits of ion ...
Isabelle, Gourfinkel-An +6 more
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Genetics of Idiopathic Epilepsies
Epilepsia, 2005Summary: Purpose: To search for clues to molecular genetics of common idiopathic epilepsy syndromes. Genetic defects have been identified recently in certain inherited epilepsy syndromes in which the phenotypes are similar to those of common idiopathic epilepsies.
Shinichi, Hirose +3 more
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Idiopathic generalized epilepsies
2013Idiopathic generalized epilepsies (IGEs) may start in infancy, childhood, or adolescence, but some have an onset in adulthood. They are genetically determined and affect otherwise healthy people of both sexes and all races, and are generally lifelong. Some, however, are age related. IGEs account for nearly a third of all epilepsies.
Roberto H, Caraballo +1 more
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Clinical Techniques in Small Animal Practice, 1998
Idiopathic epilepsy is one of the most common and treatable neurologic diseases of small animals. The objectives of this article are to present a clinical overview and practical approach to its management. A review of terminology, epidemiologic issues, diagnosis, differential diagnosis, and general principles of treatment are presented.
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Idiopathic epilepsy is one of the most common and treatable neurologic diseases of small animals. The objectives of this article are to present a clinical overview and practical approach to its management. A review of terminology, epidemiologic issues, diagnosis, differential diagnosis, and general principles of treatment are presented.
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2013
In this chapter we include a series of epilepsies with onset in pediatric age characterized by focal seizures, idiopathic etiology, normal psychomotor development, and a benign course related to the spontaneous remission of seizures without sequelae. These entities are age-dependent and seizures tend to disappear spontaneously.
Federico, Vigevano +2 more
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In this chapter we include a series of epilepsies with onset in pediatric age characterized by focal seizures, idiopathic etiology, normal psychomotor development, and a benign course related to the spontaneous remission of seizures without sequelae. These entities are age-dependent and seizures tend to disappear spontaneously.
Federico, Vigevano +2 more
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Idiopathic generalized epilepsies
2012Abstract The idiopathic generalized epilepsies (IGEs) are a spectrum of epilepsy syndromes that are characterized by seizures of generalized onset, and by known or presumed genetic etiology. These syndromes occur frequently in adults and children aged above 2 years.
Amy, Kao, Pooja M, Rao
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Genetics of idiopathic epilepsies
2013One of the most exciting areas in epilepsy has been the explosion in our understanding of the genetics of the epilepsies over the last decade. Built on a long history of careful clinical genetic studies of the epilepsies, the relatively recent discovery of epilepsy genes has enabled insights into pathways causing seizure disorders.
Rima, Nabbout, Ingrid E, Scheffer
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Veterinary Clinics of North America: Small Animal Practice, 2000
Idiopathic epilepsy is a chronic condition characterized by recurrent seizures for which there is no identifiable cause. It is the most common neurologic disorder in the dog. This article discusses the diagnostic evaluation and rational treatment of dogs with recurrent seizures.
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Idiopathic epilepsy is a chronic condition characterized by recurrent seizures for which there is no identifiable cause. It is the most common neurologic disorder in the dog. This article discusses the diagnostic evaluation and rational treatment of dogs with recurrent seizures.
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Pharmacotherapy of idiopathic generalized epilepsies
Expert Opinion on Pharmacotherapy, 2008Idiopathic generalized epilepsies (IGE) represent about 20% of all epilepsies, are genetically determined and comprise several subgroups of syndromes. Although complete seizure control is achievable in about 80% of patients with IGE syndromes, a substantial group remains with inadequate control and unsatisfactory long-term outcome.
CURATOLO, PAOLO +3 more
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Genetics of idiopathic epilepsies
2012Abstract Most idiopathic epilepsies are oligogenic or polygenic disorders that show extreme clinical and etiological heterogeneity. Only a few monogenic idiopathic epilepsies are known; although rare, they have contributed tremendously to our understanding of basic pathomechanisms in epileptogenesis.
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