Results 51 to 60 of about 38,167 (281)

Psychotropic medication use among community dwellers with and without Parkinson's disease – A nationwide cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen   +4 more
wiley   +1 more source

Deficiency of selenium and zinc as a causative factor for idiopathic intractable epilepsy

open access: yes, 2021
Purpose: The accumulation of free radicals may lead to seizures and increase the risk of their recurrence. Glutathione peroxidase and superoxide dismutase are 2 major enzymes that are involved in antioxidative defense mechanisms. Selenium (Se), zinc (Zn),
Seven, Mehmet   +4 more
core   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba   +7 more
wiley   +1 more source

Prevalence and characteristics of visual aura in idiopathic generalized epilepsy

open access: yes, 2012
Some patients with idiopathic/genetic generalized epilepsy (IGE) experience visual aura, which can confuse the diagnosis. We sought to determine the frequency and characteristics of visual auras in IGE patients.
Gungor-Tuncer, Ozlem   +5 more
core   +1 more source

Features of neurological and neuropsychological changes in the initial stages of encephalopathy in patients with idiopathic epilepsy [PDF]

open access: yesСаратовский научно-медицинский журнал, 2011
Aim. The study was undertaken to identify the features of neurological and cognitive changes in idiopathic epilepsy based on neurological and neuropsychological research. Methods.
Burdakov V.V. Gumalatova N.V.
doaj  

BRAIN BIOELECTRIC ACTIVITY IN CHILDREN WITH IDIOPATHIC EPILEPSY

open access: yesЭпилепсия и пароксизмальные состояния, 2018
The aim was to study the bioelectrical activity of the brain in children with idiopathic epilepsy. Using clinical, neurological and neurophysiological methods, we examined 60 children (32 boys, 53% and 28 girls, 47%) aged 5 to 10 years old.Results.
Yo. N. Majidova, M. I. Abdullayeva
doaj   +1 more source

Cortical neuronal loss and hippocampal sclerosis are not detected by voxel-based morphometry in individual epilepsy surgery patients

open access: yes, 2009
Voxel-based morphometry (VBM) has detected differences between brains of groups of patients with epilepsy and controls, but the sensitivity for detecting subtle pathological changes in single subjects has not been established.
Martinian, Lillian   +20 more
core   +1 more source

THE INCIDENCE OF VARIOUS FORMS OF IDIOPATHIC FOCAL EPILEPSY IN CHILDREN

open access: yesЭпилепсия и пароксизмальные состояния, 2016
The structure of idiopathic focal epilepsy was studied with 1118 patients who have diagnosis «epilepsy» with debut of seizures at the age from first days of life to 18 years.
K. Yu. Mukhin, M. B. Mironov
doaj  

A guide to neuromodulation in drug‐resistant epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh   +10 more
wiley   +1 more source

The prognosis of idiopathic generalized epilepsy [PDF]

open access: yesEpilepsia, 2012
SummaryPrognosis describes the trajectory and long‐term outcome of a condition. Most studies indicate a better prognosis in idiopathic generalized epilepsy (IGE) in comparison with other epilepsy syndromes. Studies looking at the long‐term outcome of different IGE syndromes are relatively scant.
Udaya, Seneviratne   +2 more
openaire   +2 more sources

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