Results 81 to 90 of about 57,146 (292)

TRIM39-RPP21 Variants (∆19InsCCC) Are Not Associated with Juvenile Idiopathic Epilepsy in Egyptian Arabian Horses. [PDF]

open access: yes, 2019
Juvenile idiopathic epilepsy (JIE) is an inherited disease characterized by recurrent seizures during the first year of life in Egyptian Arabian horses. Definitive diagnosis requires an electroencephalogram (EEG) performed by a veterinary specialist.
Aleman, Monica   +5 more
core   +2 more sources

Evolution of the European Medicines Agency clinical guidelines for epilepsy drug development between 2010 and 2025: A comparative analysis by the ILAE Task Force on Regulatory Affairs

open access: yesEpilepsia, EarlyView.
Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin   +7 more
wiley   +1 more source

Questionnaire survey on the usage of antiseizure drugs for dogs and cats in Japanese veterinary hospitals (2020)

open access: yesVeterinary Medicine and Science, 2022
Epilepsy is the most common neurological disorder in veterinary medicine. Recently, evidence‐based recommendations or systematic reviews for using antiseizure drugs (ASDs) in dogs and cats have been published, but there are many differences in economic ...
Satoshi Mizuno   +2 more
doaj   +1 more source

Appearance of the canine meninges in subtraction magnetic resonance images [PDF]

open access: yes, 2014
The canine meninges are not visible as discrete structures in noncontrast magnetic resonance (MR) images, and are incompletely visualized in T1‐weighted, postgadolinium images, reportedly appearing as short, thin curvilinear segments with minimal ...
Frean, S P   +3 more
core   +2 more sources

Patterns of seizure frequency reduction in clinical trial participants with lower baseline seizure frequency

open access: yesEpilepsia, EarlyView.
Abstract Objective Inclusion and exclusion criteria of clinical trials for seizures aim to select representative participants with a high enough seizure frequency to evaluate the efficacy of treatment in a relatively short double‐blind period. To inform the selection of seizure frequency‐based inclusion criteria, we evaluated the association between ...
Wesley T. Kerr   +5 more
wiley   +1 more source

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

open access: yesEpilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie   +10 more
wiley   +1 more source

The social cognition of medical knowledge, with special reference to childhood epilepsy [PDF]

open access: yes, 2009
This paper arose out of an engagement in medical communication courses at a Gulf university. It deploys a theoretical framework derived from a (critical) sociocognitive approach to discourse analysis in order to investigate three aspects of medical ...
Appleton R.   +39 more
core   +3 more sources

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

open access: yesEpilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze   +19 more
wiley   +1 more source

Evaluation of Fear in Idiopathic Epilepsy Using Population-Based Survey and Bhalla-Gharagozli Fear in Epilepsy Questionnaire (BG-FEQ)

open access: yesNeuropsychiatric Disease and Treatment, 2020
Kurosh Gharagozli,1– 3 Elham Lotfalinezhad,4,5 Fatemeh Amini,5 Vida Saii,1 Devender Bhalla6– 8 1Iran Epilepsy Association, Tehran, Iran; 2Department of Neurology, Shahid Beheshti University of Medical Sciences, Tehran, Iran; 3Brain Mapping ...
Gharagozli K   +4 more
doaj  

Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]

open access: yes, 2015
BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR   +8 more
core   +1 more source

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