Results 111 to 120 of about 13,437 (222)

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 673-683, September 2026.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba   +7 more
wiley   +1 more source

Altered neurovascular coupling in children with idiopathic generalized epilepsy. [PDF]

open access: yesCNS Neurosci Ther, 2023
Hu J   +8 more
europepmc   +1 more source

Relationships between pre‐, post‐, and inter‐ictal psychiatric symptoms in patients with epilepsy

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
Abstract Aim Although pre‐ and post‐ictal psychiatric symptoms (PS) in patients with epilepsy are well known, the prevalences and pathophysiologies remain unclear. We investigated the prevalences and durations of pre‐ and post‐ictal PS, related factors, and associations between pre‐ and post‐ictal PS. Methods In the Neuropsychiatry Department of Kurume
Shingo Yasumoto   +6 more
wiley   +1 more source

Artificial Intelligence in Veterinary Neurology: Comparative Insights From Human Medicine and Cross‐Species Technology Transfer

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Overview of major artificial intelligence applications in veterinary neurology, including neuroimaging, seizure prediction, gait and pain assessment, and prognostic modeling. The figure also highlights cross‐species technology transfer and key challenges, such as limited data, lack of standardization, and ethical concerns.
Kianoush Saberi   +12 more
wiley   +1 more source

Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile

open access: yesAnnals of Neurology, Volume 100, Issue 2, Page 255-267, August 2026.
Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale   +17 more
wiley   +1 more source

Psychotropic medication use among community dwellers with and without Parkinson's disease – A nationwide cohort study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2701-2710, August 2026.
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen   +4 more
wiley   +1 more source

CLINICAL FEATURES OF FOCAL EPILEPSY WITH SECONDARY BILATERAL SYNCHRONIZATION ON EEG AMONG ADOLESCENTS

open access: yesЭпилепсия и пароксизмальные состояния, 2016
: current work is dedicated to analysis of features of clinical and encephalographic manifestations of focal epilepsy with secondary bilateral synchronization on EEG and onset in adolescence.
T. R. Sadykov   +3 more
doaj  

Treatment outcomes in women with idiopathic generalized epilepsy. [PDF]

open access: yesActa Neurol Scand, 2022
Kiiski R   +5 more
europepmc   +1 more source

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