Results 111 to 120 of about 13,437 (222)
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba +7 more
wiley +1 more source
Altered neurovascular coupling in children with idiopathic generalized epilepsy. [PDF]
Hu J +8 more
europepmc +1 more source
Relationships between pre‐, post‐, and inter‐ictal psychiatric symptoms in patients with epilepsy
Abstract Aim Although pre‐ and post‐ictal psychiatric symptoms (PS) in patients with epilepsy are well known, the prevalences and pathophysiologies remain unclear. We investigated the prevalences and durations of pre‐ and post‐ictal PS, related factors, and associations between pre‐ and post‐ictal PS. Methods In the Neuropsychiatry Department of Kurume
Shingo Yasumoto +6 more
wiley +1 more source
Overview of major artificial intelligence applications in veterinary neurology, including neuroimaging, seizure prediction, gait and pain assessment, and prognostic modeling. The figure also highlights cross‐species technology transfer and key challenges, such as limited data, lack of standardization, and ethical concerns.
Kianoush Saberi +12 more
wiley +1 more source
Causality Analysis to the Abnormal Subcortical-Cortical Connections in Idiopathic-Generalized Epilepsy. [PDF]
Qin Y, Li S, Yao D, Luo C.
europepmc +1 more source
Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile
Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale +17 more
wiley +1 more source
GABRG2 C588T Polymorphism Is Associated with Idiopathic Generalized Epilepsy but Not with Antiepileptic Drug Resistance in Pakistani Cohort. [PDF]
Saleem T +5 more
europepmc +1 more source
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen +4 more
wiley +1 more source
: current work is dedicated to analysis of features of clinical and encephalographic manifestations of focal epilepsy with secondary bilateral synchronization on EEG and onset in adolescence.
T. R. Sadykov +3 more
doaj
Treatment outcomes in women with idiopathic generalized epilepsy. [PDF]
Kiiski R +5 more
europepmc +1 more source

