Results 131 to 140 of about 24,154 (255)

iSPHYNCS: Unsupervised Clustering in Questionnaires and Metadata Reveals Distinct Subtypes in the Narcolepsy Borderland

Journal of Sleep Research, EarlyView.
Study overview and clustering results in the iSPHYNCS cohort. Participant demographics are summarized in a baseline table. Questionnaire data and metadata were processed through an unsupervised clustering pipeline. A Sankey plot illustrates individual assignment across clusters by diagnostic group.
Rafael Morand, Livia Fregolente, Julia van der Meer, Elena S. Wenz, Annina Helmy, Lorenzo Brigato, Jan D. Warncke, Kseniia Zub, Ramin Khatami, Zhongxing Zhang, Sigrid von Manitius, Silvia Miano, Jens Acker, Mathias Strub, Ulf Kallweit, Gert Jan Lammers, Athina Tzovara, Claudio L. A. Bassetti, Stavroula Mougiakakou, Markus H. Schmidt   +19 more
wiley   +1 more source

Brivaracetam‐associated manic episode in a patient with bipolar disorder: A case report

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
A patient with Bipolar I disorder developed manic symptoms following the initiation of brivaracetam for focal epilepsy. Although brivaracetam is generally considered to have favorable psychiatric tolerability, this case highlights a potential risk of mood destabilization in patients with underlying bipolar disorder.
Mihoko Kawai, Jun Miyata, Kousuke Kanemoto   +2 more
wiley   +1 more source

Pathophysiological role of extrasynaptic GABAA receptors in typical absence epilepsy [PDF]

, 2011
GABA is the principal inhibitory neurotransmitter in the mammalian CNS. It acts via two classes of receptors, the GABAA, a ligand gated ion channel (ionotropic receptor) and the metabotropic G-protein coupled GABAB receptor.
Crunelli, Vincenzo, Di Giovanni, Giuseppe, Errington, Adam C.   +2 more
core  

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A Comprehensive Review of Types, Pathophysiology, and Treatment Approaches

Brain and Behavior, Volume 16, Issue 5, May 2026.
Chronic inflammatory demyelinating polyneuropathy is an autoimmune disorder causing demyelination, leading to distal weakness, sensory loss, and autonomic dysfunction. Immune activation triggers macrophage‐mediated myelin damage and conduction failure.
Ayesha Khan, Arsal Khan, Kuldeep Dalpat Rai, Anzel Saeed, Harsh Kumar, Aneesh Kumar Sangtiani, Tehreem Fatima, Muhammad Tanveer Alam, Faiza Rajput, Sakshi Chawla, Hussain Haider Shah, Humaira Kalam   +11 more
wiley   +1 more source

The Impact of an Epilepsy Self-Management Program on Healthcare Utilization and Related Costs [PDF]

, 2016
During a summer 2015 internship at Dartmouth-Hitchcock Medical Center, I was part of a team studying the cost effectiveness of Home Based Self-Management and Cognitive Training Changes Lives (HOBSCOTCH), a self-management program for memory impairment in
Dwyer, Emily
core   +2 more sources

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Neurological Disorders in Dogs: A Retrospective Analysis of Prevalence, Aetiology, Lesion Locations, and Regional Variations in Northeastern Iran

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This retrospective study evaluated 422 dogs with neurological disorders among 9131 canine referrals over 8.5 years in northeastern Iran. Infectious diseases, particularly canine distemper (33.2%), were the leading cause, followed by trauma and idiopathic conditions. The prosencephalon was the most frequently affected anatomical region.
Ali Behrouzian, Ali Asghar Sarchahi, Hadi Jabbari Noghabi   +2 more
wiley   +1 more source

High‐Fat and Low‐Carbohydrate Dietary Environments Are Linked to Reduced Idiopathic Epilepsy Incidence and Prevalence

Annals of Clinical and Translational Neurology
Dietary manipulations like ketogenic diets are established interventions for recalcitrant epilepsy. However, it remains unknown whether specific macronutrient exposure through dietary environments could possibly extend to primary preventive qualities ...
Duan Ni, Alistair Senior, David Raubenheimer, Stephen J. Simpson, Ralph Nanan   +4 more
doaj   +1 more source

Long‐Term Speech Outcomes in Moderate‐to‐Severe Childhood Speech Sound Disorder: A Systematic Review

International Journal of Language &Communication Disorders, Volume 61, Issue 3, May/June 2026.
ABSTRACT Background Parents of children with moderate‐to‐severe speech sound disorder presenting to clinic want to understand prognosis for their child; however, there is unclear evidence as to the specific long‐term speech outcomes in this group.
Alexandra J. Garrett, Sermin Tukel, Angela T. Morgan   +2 more
wiley   +1 more source

A Scoping Review of the Associations Between Ascariasis, Helicobacter pylori Infection and Gastric Pathologies

Parasite Immunology, Volume 48, Issue 5, -Not available-.
ABSTRACT Ascaris infection—ascariasis—is the most common human parasitic worm infection worldwide and induces damage and cellular changes within the stomach. Helicobacter pylori is a bacterium of the stomach that also causes gastric pathologies globally. Importantly, Ascaris, H.
Nina L. Tang, Jacob J. Williams, Jennifer Stockton, Maria Elena Bottazzi, Jill E. Weatherhead   +4 more
wiley   +1 more source