Results 51 to 60 of about 13,331 (166)

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Incidence rate of different forms of idiopathic childhood focal epilepsy

Эпилепсия и пароксизмальные состояния, 2016
The structure of idiopathic focal forms of epilepsy was investigated on 1118 patients with diagnosis of epilepsy, and aged from the first days of life to 18 years. Their age enabled to monitor the debut of seizures.
K. Yu. Mukhin, M. B. Mironov, . ., . ., . ., . ., . ., . .   +7 more
doaj  

Generalized spike–waves in idiopathic generalized epilepsies: Does their frequency matter?

Brain and Behavior
Objectives We hypothesized that the frequency (in Hertz) of generalized spike–waves (GSWs) in patients with idiopathic generalized epilepsy (IGE) has associations with the syndromic diagnosis as well as with the prognosis of patients (their response to ...
Ali A. Asadi‐Pooya, Mohsen Farazdaghi
doaj   +1 more source

Neuropsychological-EEG Activation in Genetic Generalized Epilepsy

Pediatric Neurology Briefs, 2015
Investigators from Lithuanian University of Health Sciences, Kaunas, evaluated the effects of neuropsychological activation (NPA) tasks on epileptiform discharges (ED) in adolescents with idiopathic generalized epilepsy (IGE) and in comparison with ...
J Gordon Millichap, John J Millichap
doaj   +1 more source

Metabolic mimicry of perioral myoclonia with absences: A signature of thalamocortical instability in childhood‐onset ornithine transcarbamylase deficiency

Epileptic Disorders, EarlyView.
José Augusto Bragatti, Letícia Grigoletto   +1 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Frontiers in EEG as a tool for the management of pediatric epilepsy: Past, present, and future

Epilepsia Open, EarlyView.
Abstract Electroencephalography (EEG) has evolved into an indispensable tool in pediatric epilepsy, fundamentally transforming the diagnosis, classification, and management of this condition. This review chronicles the historical journey of EEG from its groundbreaking inception to its current pivotal role in delineating distinct pediatric epilepsy ...
Hiroki Nariai
wiley   +1 more source

Polygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure events

Nature Communications
A diagnosis of epilepsy has significant consequences for an individual but is often challenging in clinical practice. Novel biomarkers are thus greatly needed.
Henrike O. Heyne, Fanny-Dhelia Pajuste, Julian Wanner, Jennifer I. Daniel Onwuchekwa, Reedik Mägi, Aarno Palotie, FinnGen, Estonian Biobank research team, Reetta Kälviainen, Mark J. Daly   +9 more
doaj   +1 more source

Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study

Frontiers in Public Health
BackgroundIdiopathic epilepsy is a major global health burden that causes premature death and disability. Previous studies have systematically analyzed trends in the burden of idiopathic epilepsy. However, analyses of the impact of social factors, health
Xuewen Rong, Dongting Yu, Wei Zhao, Jingyu Xiao, Du Feng, Gengfeng Chen, Zemeng Cao, Liming Shu   +7 more
doaj   +1 more source

Functional neuroimaging abnormalities in idiopathic generalized epilepsy

NeuroImage: Clinical, 2014
Magnetic resonance imaging (MRI) techniques have been used to quantitatively assess focal and network abnormalities. Idiopathic generalized epilepsy (IGE) is characterized by bilateral synchronous spike–wave discharges on electroencephalography (EEG) but
Megan L. McGill, Orrin Devinsky, Xiuyuan Wang, Brian T. Quinn, Heath Pardoe, Chad Carlson, Tracy Butler, Ruben Kuzniecky, Thomas Thesen   +8 more
doaj   +1 more source