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Hypereosinophilic Syndrome: Contemporary Approaches to Molecular-Genetic Diagnostics and Gene-Engineered Biologic Therapy

Медицина и биотехнологии
Introduction. In recent years, there has been a growing interest among researchers in conditions associated with hypereosinophilia and the therapeutic potential of genetically engineered biological agents.
Larisa A. Balykova, Anna V. Krasnopolskaya, Marina V. Shirmankina, Diva Augusta T. Mendes, Anastasia M. Khanina   +4 more
doaj   +1 more source

Algorithms in Allergy: Treatment of Hypereosinophilic Syndromes, 2026 Update

Allergy, EarlyView.
Guillaume Lefèvre, Florence Roufosse, Giacomo Emmi, Andreas Reiter, Emmanuel Ledoult, Jean‐Emmanuel Kahn   +5 more
wiley   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, Volume 78, Issue 6, Page 1196-1205, June 2026.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Hypereosinophilic vasculitis with Raynaud phenomenon presentation: a case report

The Egyptian Heart Journal, 2023
Background Previous case series have reported idiopathic eosinophilic vasculitis as a potential manifestation of hypereosinophilic syndrome (HES). This condition is characterized by digital necrotizing, systemic vasculitis that affects varying-sized ...
Duy Le Cao Phuong, Hoa Bui The, Quan Vo Duy   +2 more
doaj   +1 more source

Algorithms in Allergy: Diagnosis of Hypereosinophilic Syndromes, 2026 Update

Allergy, EarlyView.
Guillaume Lefèvre, Florence Roufosse, Giacomo Emmi, Andreas Reiter, Emmanuel Ledoult, Jean‐Emmanuel Kahn   +5 more
wiley   +1 more source

Polyneuropathy in hypereosinophilic syndrome

, 1988
We investigated two patients with the idiopathic hypereosinophilic syndrome and peripheral neuropathy. Clinical, EMG, and pathological findings were consistent with axonal polyneuropathy.
Giannini C., Nardelli E., Curro-Dossi B., Lucci B., Tezzon F., Laperchia N., Monaco S., Rizzuto N.   +7 more
core   +1 more source

Chronic Eosinophilic Leukemia-Not Otherwise Specified (CEL-NOS) - Idiopathic Hypereosinophilic Syndrome (IHES) [PDF]

, 2019
Chronic eosinophilic leukemia (CEL) not otherwise specified (NOS) and idiopathic hypereosinophilic syndrome (HES) are rare hematologic disorders characterized by chronic, unexplained eosinophilia with manifestation of organ involvement related to ...
Mohamed, Anwar N
core   +1 more source

Hypereosinophilia-associated acute intradialytic hypotension: a case report [PDF]

Kosin Medical Journal
Eosinophilia in patients undergoing hemodialysis (HD) is rare but can cause severe complications including intradialytic hypotension. Hypereosinophilia-associated acute intradialytic hypotension (HAIDH) typically develops within minutes of HD initiation ...
Ji Hyun Jeon, Sang Heon Song
doaj   +1 more source

Wells syndrome: clinical findings and treatment management in a large cohort of 48 patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 5, Page 644-656, May 2026.
Summary Background and Objectives: Wells syndrome (WS) is a rare inflammatory skin disorder typically characterized by erythematous, edematous, and pruritic plaques. Despite its distinct histopathological features, WS remains an underdiagnosed disease due to its variable clinical presentations and overlap with other dermatological conditions.
Marco Adriano Chessa, Silvia Robuffo, Tullio Brunetti, Luca Rapparini, Bianca Maria Piraccini, Cosimo Misciali, Beatrice Raone, Iria Neri, Federica Filippi   +8 more
wiley   +1 more source

Supplemental Material - Anesthetic Management of a Large Right Ventricular Mass due to Idiopathic Hypereosinophilic Syndrome in a Patient Undergoing Cardiac Surgery, a Case Report

, 2022
Supplemental Material for Anesthetic Management of a Large Right Ventricular Mass due to Idiopathic Hypereosinophilic Syndrome in a Patient Undergoing Cardiac Surgery, a Case Report by Giacomo Scorsese, DO, Austin Hake, BS, Alexa Christophides, BS, MS ...
Alexa Christophides (13926545), Austin Hake (13926542), Jeremy Poppers (13926548), Giacomo Scorsese (13926539), Eric Zabirowicz (13926551)   +4 more
core   +1 more source