Results 111 to 120 of about 3,776 (207)

Lauflumide (NLS-4) Is a New Potent Wake-Promoting Compound

open access: yesFrontiers in Neuroscience, 2018
Psychostimulants are used for the treatment of excessive daytime sleepiness in a wide range of sleep disorders as well as in attention deficit hyperactivity disorder or cognitive impairment in neuropsychiatric disorders.
Gianina Luca   +9 more
doaj   +1 more source

Genetic Analysis of Histamine Signaling in Larval Zebrafish Sleep [PDF]

open access: yes, 2017
Pharmacological studies in mammals and zebrafish suggest that histamine plays an important role in promoting arousal. However, genetic studies using rodents with disrupted histamine synthesis or signaling have revealed only subtle or no sleep/wake ...
Chen, Audrey   +3 more
core   +1 more source

Obesity and sleep disturbance: the chicken or the egg? [PDF]

open access: yes, 2018
Epidemiological studies suggested an association between obesity and sleep disturbances. Obstructive sleep apnea is the most prevalent type of obesity-related sleep disorder that lead to an increased risk for numerous chronic health conditions.
Annunziata, G   +6 more
core   +1 more source

Cross-species evidence for a developmental origin of adult hypersomnia with loss of synaptic adhesion molecules beat-Ia/CADM2

open access: yesNature Communications
Idiopathic hypersomnia (IH) is a poorly understood sleep disorder characterized by excessive daytime sleepiness despite normal nighttime sleep. Combining human genomics with behavioral and mechanistic studies in fish and flies, we uncover a role for beat-
Kyla Mace   +9 more
doaj   +1 more source

Pathophysiological Models of Hypersomnolence Associated With Depression

open access: yesBiological Psychiatry Global Open Science
Up to 25% of patients with depression experience hypersomnolence (e.g., excessive daytime sleepiness, hypersomnia, and/or sleep inertia), which is associated with treatment resistance, overall poorer outcomes, and safety concerns while driving ...
Christophe Moderie, Diane B. Boivin
doaj   +1 more source

Does major depressive disorder cause osteoporosis in a young man? [PDF]

open access: yes, 2006
We recently reviewed the literature about major depressive disorder (MDD) as an additional risk factor for osteoporosis (1, 2). Most of the studies examining the association between depression and osteoporosis have been conducted in women whereas the
Boscaro, Marco   +5 more
core  

Self-help cognitive-behavioral therapy for insomnia (CBT-1): a systematic review of randomized controlled trials [PDF]

open access: yes, 2013
Theme: Insomnia - new insight into development and manageThis study aimed to review current literature, examine the efficacy, adherence, acceptability, and attrition rate of self-help CBT-I, and to explore possible factors that might contribute to the ...
Chung, KF   +4 more
core  

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