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Idiopathic hypersomnia: a neurological dilemma
Sleep Medicine Reviews, 2001Historically, there has been some confusion with wakefulness test (MWT), explore the degree (or lack) of alertness, rather than real changes in sleep the use of terms such as “narcolepsy” “excessive daytime sleepiness” and “hypersomnia” [1]. The structure and amount.
Christian, Guilleminault +1 more
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Update on treatment for idiopathic hypersomnia
Expert Opinion on Investigational Drugs, 2018Idiopathic hypersomnia (IH) is a poorly characterized orphan central disorder of hypersomnolence responsible for excessive daytime sleepiness (EDS), prolonged nighttime sleep and sleep inertia that often require long-term symptomatic stimulant medication. To date, no drug has currently the authorization for the treatment of IH patients worldwide. Areas
Elisa, Evangelista +2 more
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Pflügers Archiv European Journal of Physiology, 1996
Polysomnographic studies in hypersomniac patients with mood disorders are rare. Previous studies investigated patients with a severe mood disorder, but our study was done in patients with dysthymia, who complained of sleepiness. Mean sleep latency test (MSLT) and continuous polysomnographic recording (CPR) were done in 12 dysthymic patients, in ...
L, Dolenc, A, Besset, M, Billiard
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Polysomnographic studies in hypersomniac patients with mood disorders are rare. Previous studies investigated patients with a severe mood disorder, but our study was done in patients with dysthymia, who complained of sleepiness. Mean sleep latency test (MSLT) and continuous polysomnographic recording (CPR) were done in 12 dysthymic patients, in ...
L, Dolenc, A, Besset, M, Billiard
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Narcolepsy and Idiopathic Hypersomnia
2011Excessive daytime sleepiness (EDS) is a common symptom that is part of many different medical, neurologic, psychiatric, and sleep disorders. The terms “excessive daytime sleepiness” and “hypersomnia” are often used interchangeably; however, the term “hypersomnia” should be reserved to refer to a group of disorders in which the primary complaint is ...
Imran Ahmed, Michael Thorpy
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Narcolepsy and Idiopathic Hypersomnia
2015Recent progress for understanding the pathophysiology of excessive daytime sleepiness (EDS) particularly owes itself to the discovery of narcolepsy genes (i.e., hypocretin receptor and peptide genes) in animals in 1999 and the subsequent discovery in 2000, of hypocretin ligand deficiency (i.e., loss of hypocretin neurons in the brain) in idiopathic ...
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Narcolepsy and Idiopathic Hypersomnia
Abstract This chapter introduces the causes, clinical features, diagnosis, and treatment of central nervous system sleep disorders characterized by severe daytime sleepiness. Excessive daytime sleepiness is the propensity to fall asleep during the usual wake period, especially unintentionally dozing off while in passive situations, such ...Margaret S. Blattner, Thomas E. Scammell
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