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Insulinoma presenting as idiopathic hypersomnia
Neurological Sciences, 2010We report the case of a 32-year-old woman with a history of increased sleep need and difficulty waking up; the diagnosis of idiopathic hypersomnia was hypothesized. During ambulatory polysomnography (PSG), the patient presented an episode characterized by loss of consciousness and jerking of the four limbs.
MAESTRI M +7 more
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Update on treatment for idiopathic hypersomnia
Expert Opinion on Investigational Drugs, 2018Idiopathic hypersomnia (IH) is a poorly characterized orphan central disorder of hypersomnolence responsible for excessive daytime sleepiness (EDS), prolonged nighttime sleep and sleep inertia that often require long-term symptomatic stimulant medication. To date, no drug has currently the authorization for the treatment of IH patients worldwide. Areas
Elisa, Evangelista +2 more
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Narcolepsy and Idiopathic Hypersomnia
2011Excessive daytime sleepiness (EDS) is a common symptom that is part of many different medical, neurologic, psychiatric, and sleep disorders. The terms “excessive daytime sleepiness” and “hypersomnia” are often used interchangeably; however, the term “hypersomnia” should be reserved to refer to a group of disorders in which the primary complaint is ...
Imran Ahmed, Michael Thorpy
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Idiopathic hypersomnia, Kleine–Levin syndrome, and symptomatic hypersomnias
2017Besides obstructive sleep apnea syndrome and narcolepsy, there are a number of other causes of excessive daytime sleepiness, listed in the International Classification of Sleep Disorders, third edition, as central disorders of hypersomnolence. They include primary sleep disorders such as idiopathic hypersomnia, Kleine-Levin syndrome and a number of ...
Michel Billiard, Yves Dauvilliers
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Narcolepsy and Idiopathic Hypersomnia
2015Recent progress for understanding the pathophysiology of excessive daytime sleepiness (EDS) particularly owes itself to the discovery of narcolepsy genes (i.e., hypocretin receptor and peptide genes) in animals in 1999 and the subsequent discovery in 2000, of hypocretin ligand deficiency (i.e., loss of hypocretin neurons in the brain) in idiopathic ...
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Narcolepsy and Idiopathic Hypersomnia
Abstract This chapter introduces the causes, clinical features, diagnosis, and treatment of central nervous system sleep disorders characterized by severe daytime sleepiness. Excessive daytime sleepiness is the propensity to fall asleep during the usual wake period, especially unintentionally dozing off while in passive situations, such ...Margaret S. Blattner, Thomas E. Scammell
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Clinical considerations for the diagnosis of idiopathic hypersomnia
Sleep Medicine Reviews, 2022yves Dauvilliers +2 more
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