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Idiopathic inflammatory myopathies lack neutralising autoantibodies to type- I, II and III interferons. [PDF]
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Idiopathic inflammatory myopathies
Nature Reviews Disease Primers, 2021Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous group of autoimmune disorders with varying clinical manifestations, treatment responses and prognoses. Muscle weakness is usually the classical clinical manifestation but other organs can be affected, including the skin, joints, lungs, heart and gastrointestinal tract,
Rohit Aggarwal +2 more
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Idiopathic Inflammatory Myopathies
Indian Journal of Pediatrics, 2023Idiopathic inflammatory myopathies (IIMs) are a diverse group of diseases characterized by proximal muscle weakness and inflammation in skeletal muscle. Phenotypically, the subtypes include dermatomyositis, polymyositis, inclusion body myositis, and amyopathic dermatomyositis. The most common IIM in children is juvenile dermatomyositis (JDM).
Suma Balan, Sumanth Madan
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Epidemiology of the idiopathic inflammatory myopathies
Nature Reviews Rheumatology, 2023 The idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of systemic autoimmune diseases that affect the skeletal muscles and can also involve the skin, joints, lungs and heart. The epidemiology of IIM is obscured by changing classification criteria and the inherent shortcomings of case identification using healthcare record diagnostic ...
Hector Chinoy +2 more
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IDIOPATHIC INFLAMMATORY MYOPATHIES
Neurologic Clinics, 1997Dermatomyositis, polymyositis, and inclusion body myositis are the major categories of idiopathic inflammatory myopathy. These inflammatory myopathies are distinct clinically, histologically, and pathogenically. Features of dermatomyositis and polymyositis can overlap with those of other autoimmune connective tissue diseases.
A A, Amato, R J, Barohn
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Idiopathic inflammatory myopathies
Best Practice & Research Clinical Rheumatology, 2012Inflammatory myopathies are chronic, immune-mediated diseases characterised by progressive proximal muscle weakness. They encompass a variety of syndromes with protean manifestations. The diagnosis is based on Bohan and Peter's classification criteria, which nowadays seem to be obsolete.
Melinda, Vincze, Katalin, Danko
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Idiopathic Inflammatory Myopathies
Rheumatic Disease Clinics of North America, 1990The idiopathic inflammatory myopathies are a heterogeneous group of uncommon diseases. The incidence rate of IIM is approximately 5 cases per million population, but there appears to be an increase in the rate over the last two decades, particularly in black females.
M E, Cronin, P H, Plotz
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Idiopathic Inflammatory Myopathies
DeckerMed Neurology, 2002The idiopathic inflammatory myopathies (IIMs), also known as myositis syndromes, are a collection of heterogeneous disorders that share the common feature of chronic muscle inflammation of unknown cause. These disorders may occur in adults or children and are sometimes associated with other connective tissue disorders and a variety of cancers.
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Idiopathic Inflammatory Myopathies
Rheumatic Disease Clinics of North America, 2019Major advances have been made in the field of idiopathic inflammatory myopathies (IIM), or myositis, that are likely to facilitate development of new therapeutic strategies that have not yet been applied in this group of diseases. These advances include new classification criteria to better identify the patients with IIM, detection of several new ...
Jiří, Vencovský +2 more
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Treatment of idiopathic inflammatory myopathies
Current Opinion in Neurology, 2003This article reviews the results of recent therapeutic trials in dermatomyositis, polymyositis, and inclusion body myositis and suggests an approach to treating patients with inflammatory myopathy.We reviewed 10 double-blind, placebo-controlled therapeutic trials in patients with inflammatory myopathy.
Anthony A, Amato, Robert C, Griggs
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