Results 41 to 50 of about 7,670 (175)

Imaging assessment of calcinosis in juvenile dermatomyositis: a narrative review

Pediatric Rheumatology Online Journal
Calcinosis is a severe manifestation of juvenile and adult idiopathic inflammatory myopathies, which can lead to pain, limited range of motion, disfigurement, and infection.
Belina Y. Yi, Jessica Perfetto, Evin Rothschild, Kelly Rouster-Stevens, Amanda Robinson, Kathryn Cook, Delaney D. Ding, Andrea Eagle Child, Ovgu Kul Cinar, Barbara Limbach, Charalampia Papadopoulou, Lesley Ann Saketkoo, Adam Schiffenbauer, Heinrike Schmeling, Antonia Valenzuela, Susan Shenoi, Dawn M. Wahezi, for the CARRA JDM Calcinosis workgroup   +17 more
doaj   +1 more source

Improved Detection of Myositis‐Specific Autoantibodies Using Luciferase Immunoprecipitation Systems Assay: Comparison With Line Blot and Conventional Immunoprecipitation

Arthritis &Rheumatology, EarlyView.
Objective Myositis‐specific autoantibodies guide the diagnosis and classification of idiopathic inflammatory myopathies, but current immunoassays vary in accuracy, particularly for autoantibodies associated with interstitial lung disease. To compare the performance of the luciferase immunoprecipitation systems (LIPS) assay with line blot and ...
Peter D. Burbelo, Iago Pinal‐Fernandez, Maria Casal‐Dominguez, Xin Tian, Shijinqiu Gao, Neha Gupta, Eric W. Robbins, John A. Chiorini, Christopher A. Mecoli, Lisa Christopher‐Stine, Livia Casciola‐Rosen, Andrew L. Mammen, Sonye K. Danoff, Anthony F. Suffredini, Julio A. Huapaya   +14 more
wiley   +1 more source

Atypical presentation of anti-small ubiquitin-like modifier 1 and melanoma differentiation-associated gene 5 antibody positive dermatomyositis presenting with significant inflammatory myopathy on biopsy and normal creatine kinase levels: A case report

SAGE Open Medical Case Reports
Idiopathic inflammatory myopathies are characterized by chronic inflammation of skeletal muscle. The main subtypes of idiopathic inflammatory myopathies include dermatomyositis, polymyositis, and necrotizing autoimmune myopathies.
Srikar Sama, Nidaa Rasheed, Kyle Shen, Negar Khanlou, Karam Han, Alicia Rodriguez-Pla   +5 more
doaj   +1 more source

Sporadic inclusion body myositis in the rheumatology clinic

Indian Journal of Rheumatology, 2020
Sporadic inclusion body myositis (sIBM) is a progressive and insidious skeletal muscle disorder characterized classically by the quadriceps, wrist, and finger flexor weakness.
Fernando Henrique Carlos de Souza, Gustavo Luiz Behrens Pinto, Jean Marcos de Souza, Pablo Arturo Olivo Pallo, Leonardo Santos Hoff, Samuel Katsuyuki Shinjo   +5 more
doaj   +1 more source

Myositis mimics

Indian Journal of Rheumatology, 2021
Proximal muscle weakness in children, as well as adults, can be the presenting feature of a wide range of diseases including but not limited to the idiopathic inflammatory myopathies, muscle dystrophies, metabolic, endocrine, and drug-induced myopathies.
Sujata Ganguly, Rudrarpan Chatterjee, Abhishek Zanwar, Latika Gupta   +3 more
doaj   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

Arthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki, Masaru Takeshita, Yuki Imai, Hiroyuki Fukui, Kazunori Furuhashi, Kotaro Matsumoto, Jun Kikuchi, Keiko Yoshimoto, Yuko Kaneko   +8 more
wiley   +1 more source

Miopatías inflamatorias

Revista Médica Clínica Las Condes, 2018
RESUMEN: Las miopatías inflamatorias son un grupo heterogéneo de enfermedades adquiridas del músculo estriado esquelético que comparten la injuria muscular inmunomediada como característica común.
Jorge A. Bevilacqua, MD, PhD, Nicholas Earle, MD   +1 more
doaj   +1 more source

The impact of the COVID-19 pandemic on patients with juvenile idiopathic inflammatory myopathies

Pediatric Rheumatology Online Journal, 2023
Background Throughout the COVID-19 pandemic, there have been concerns regarding the risks of infection in patients with autoimmune disease. In this study, we investigated the impact of the pandemic on patients with juvenile idiopathic inflammatory ...
Dawn M. Wahezi, Dominique Jerome, Evin Rothschild, Belina Yi, Jeffrey Dvergsten, Stacey Tarvin, Susan Kim, Tamar Rubinstein, for the CARRA JDM workgroup   +8 more
doaj   +1 more source

Survival of Patients With Idiopathic Inflammatory Myopathies in Slovenia

Frontiers in Medicine, 2021
Background: Idiopathic inflammatory myopathies (IIMs) are rare systemic diseases associated with significant morbidity and mortality. The aim of our study was to estimate for the first time the survival of IIM patients in Slovenia.Methods: We included ...
Alojzija Hočevar, Alojzija Hočevar, Andrej Viršček, Monika Krošel, Monika Krošel, Suzana Gradišnik, Žiga Rotar, Žiga Rotar, Matija Tomšič, Matija Tomšič, Iztok Holc, Iztok Holc   +11 more
doaj   +1 more source

T Cell Plasticity in Systemic Lupus Erythematosus Revealed by Large‐Scale T Cell Receptor Repertoire and Transcriptome Studies

Arthritis &Rheumatology, EarlyView.
Objective We aimed to characterize CD4+ T cell plasticity in human systemic lupus erythematosus (SLE) by leveraging T cell receptor (TCR) repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity. Methods We used TCR
Yasuo Nagafuchi, Masahiro Nakano, Kaitlyn A. Lagattuta, Mineto Ota, Hiroaki Hatano, Haruka Takahashi, Takahiro Itamiya, Hajime Inokuchi, Soumya Raychaudhuri, Tomohisa Okamura, Keishi Fujio, Kazuyoshi Ishigaki   +11 more
wiley   +1 more source