Pathogenesis of idiopathic inflammatory myopathies [PDF]
The idiopathic inflammatory myopathies, myositis, are characterized by a chronic course with decreased muscle endurance and by infiltrates of T lymphocytes and macrophages in muscle tissue. Treatment with immunosuppressives rarely leads to recovery of muscle function, despite abolishment of inflammatory cell infiltrates in muscle tissue.
Cecilia, Grundtman, Ingrid E, Lundberg
openaire +3 more sources
Treatment of idiopathic inflammatory myopathies [PDF]
Adult idiopathic inflammatory myopathies (IIMs) are rare autoimmune disorders affecting multiple organs, making diagnosis and treatment challenging. Current management relies on immunosuppressants like corticosteroids, methotrexate, azathioprine, mycophenolate mofetil, rituximab, and intravenous immunoglobulin, though treatment responses vary across ...
Raquel Campanilho-Marques +2 more
openaire +4 more sources
Immunosuppressive and immunomodulatory therapies for idiopathic inflammatory myopathies [PDF]
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. This protocol is for two separate reviews to assess the effects (benefits and harms) of immunosuppressant and immunomodulatory treatments for the ...
Gullick, Nj +12 more
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Adult idiopathic inflammatory myopathies [PDF]
The idiopathic inflammatory myopathies represent a rare group of diseases characterized by autoimmune inflammation of skeletal muscle and other organs. There has been significant recent progress in understanding pathogenesis, phenotyping disease subtypes
Chinoy, Hector; id_orcid +2 more
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Idiopathic inflammatory myopathies: a review [PDF]
AbstractIdiopathic inflammatory myopathy (IIM) is the umbrella term including dermatomyositis (DM), polymyositis (PM), overlap myositis (OM), sporadic inclusion body myositis (IBM) and necrotising autoimmune myopathy (NAM), also known as immune‐mediated necrotising myopathy.
Catherine Ashton +4 more
openaire +2 more sources
Nonimmune mechanisms in idiopathic inflammatory myopathies [PDF]
This review encompasses the main novelties regarding nonimmune mechanisms implicated in the pathogenesis of idiopathic inflammatory myopathies (IIM)
Sandra Zampieri +11 more
core +1 more source
Current pharmacological treatment of idiopathic inflammatory myopathies [PDF]
The idiopathic inflammatory myopathies are uncommon and heterogeneous disorders. Their classification is based on distinct clinicopathologic features.
Fasano, S, Isenberg, DA, Alves, SC
core +3 more sources
A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies [PDF]
Objectives: The paediatric idiopathic inflammatory myopathies (IIMs) are a group of rare chronic inflammatory disorders of childhood, affecting muscle, skin and other organs.
Juvenile Dermatomyositis Research Group +15 more
core +1 more source
Arthrogenic Alphaviruses and Inflammatory Myopathies [PDF]
There is increasing evidence to suggest that viruses have aetiological roles in the idiopathic inflammatory myopathies. Arthrogenic alphaviruses (such as chikungunya virus, Ross River virus and sindbis virus) are known to cause outbreaks of polyarthritis
Suresh Mahalingam +3 more
core +1 more source
Autoantibody testing in idiopathic inflammatory myopathies [PDF]
Contains fulltext : 207009.pdf (Publisher’s version ) (Open Access)The diagnosis and classification of idiopathic inflammatory myopathies are based mainly on clinical and histological features.
Saris, C.G.J. +7 more
core +1 more source

