Results 91 to 100 of about 1,385 (194)

A hypothesis on treatment strategy of severe multicentric Castleman disease with continuous renal replacement therapy

Journal of Cellular and Molecular Medicine, Volume 28, Issue 17, September 2024.
Abstract Castleman disease (CD) is a rare lymphoproliferative disorder, with non‐specific clinical manifestations, often delayed diagnosis and treatment, which pose a significant challenge in the present times. Patients diagnosed with this disease have poor prognosis due to the limited treatment options.
Cătălin Constantinescu, David Kegyes, Bogdan Tigu, Vlad Moisoiu, Olga Grăjdieru, Andrea Szekely, Evangelos Terpos, Ciprian Tomuleasa   +7 more
wiley   +1 more source

Successful treatment with bortezomib in combination with dexamethasone in a middle-aged male with idiopathic multicentric Castleman’s disease: A case report

Open Medicine
Multicentric Castleman disease (MCD) is a heterogeneous, life-threatening disease. A subgroup of HIV-negative and HHV-8-negative MCD is defined as idiopathic MCD (iMCD) with a poor prognosis.
Li Hongling, He Yang, Wang Yongying, Xu Mengwei   +3 more
doaj   +1 more source

When idiopathic multicentric Castleman disease meets COVID-19: a multicenter retrospective study from China

Therapeutic Advances in Hematology
Idiopathic multicentric Castleman disease (iMCD) is a rare and cytokine storm-driven inflammatory disorder. The exact cause of iMCD is still unknown, although several hypotheses have been proposed.
Yi Liu, Xuejiao Yin, Dan Xu, Yunfei Lv, Li Zhu, Min Yang, Qiumei Yao, Jie Jin, Li Huang, Haitao Meng, Liangshun You   +10 more
doaj   +1 more source

Chronic urticaria as a manifestation of multicentric Castleman disease treated with rituximab

JEADV Clinical Practice, Volume 3, Issue 2, Page 710-713, June 2024.
Capsule SummaryWe present the case of a 26‐year‐old female with chronic urticaria (CU) with systemic symptoms in whom comprehensive laboratory and imaging studies led to the diagnosis of idiopathic multicentric Castleman disease. Treatment with rituximab induced resolution of CU. The association between these two entities is rare, and common autoimmune
Osorio‐Aragón I. Yolanda, Milián‐Solís Ximena, Berumen‐Glinz Cristina, Vargas C. Estefanía, Vega‐Memije M. Elisa, Andrade‐Rojas J. Jose, Contreras‐Solis M. Fernanda, González‐Hernández Isaac   +7 more
wiley   +1 more source

Rheumatoid arthritis-like active synovitis with T-cell activation in a case of idiopathic multicentric Castleman disease [PDF]

, 2019
RATIONALE: Idiopathic multicentric Castleman disease (iMCD) is a systemic disease with multiple regions of lymphadenopathy and systemic symptoms and associated with rheumatoid arthritis (RA) and collagen diseases. However, few reported have described the
Endo Yushiro, Ichinose Kunihiro, Igawa Takashi, Iwamoto Naoki, Kawakami Atsushi, Kawashiri Shin-ya, Koga Tomohiro, Nakamura Hideki, Niino Daisuke, Okamoto Momoko, Origuchi Tomoki, Otsuka Mizuna, Shimizu Toshimasa, Sumiyoshi Remi, Takatani Ayuko, Tamai Mami, Tsuji Sosuke   +16 more
core   +2 more sources

Primary cutaneous plasmacytosis successfully treated with topical corticosteroids and psoralen plus ultraviolet A: A case report

Clinical Case Reports, Volume 12, Issue 3, March 2024.
Key clinical message We present a case of primary cutaneous plasmacytosis without systemic involvement. The patient received topical corticosteroids and psoralen plus ultraviolet A therapy, showing significant improvement. Continuous monitoring is underway despite the rarity of systemic manifestations.
Thanyathorn Nuchanatanon, Settanan Plangsiri, Teerapong Rattananukrom   +2 more
wiley   +1 more source

The application of a multidisciplinary approach in the diagnosis of Castleman disease and Castleman‐like lymphadenopathies: A 20‐year retrospective analysis of clinical and pathological features

British Journal of Haematology, Volume 204, Issue 2, Page 534-547, February 2024.
Summary Background Castleman disease (CD) comprises a group of rare and heterogeneous haematological disorders, including unicentric (UCD) and multicentric (MCD) forms, the latter further subdivided into HHV8‐MCD, POEMS‐MCD and idiopathic‐MCD (iMCD). However, according to the Castleman Disease Collaborative Network guidelines, the diagnosis of CD can ...
Sabrina Pelliccia, Evelina Rogges, Antonello Cardoni, Gianluca Lopez, Esmeralda Conte, Anna Laura Faccini, Rita De Vito, Katia Girardi, Antonella Bianchi, Ombretta Annibali, Stefano Fratoni, Daniele Remotti, Gioia De Angelis, Carla Giordano, Giovanna Palumbo, Stefania Scarpino, Flavia Del Porto, Maria Paola Bianchi, Francesca Di Gregorio, Agostino Tafuri, Arianna Di Napoli   +20 more
wiley   +1 more source

A case of idiopathic multicentric Castleman's disease with secondary autoimmune neutropenia

Respirology Case Reports, Volume 12, Issue 1, January 2024.
Thrombocytopenia and anaemia are common complications of Idiopathic multicentric Castleman's disease (iMCD)‐induced hematologic disorders, however, neutropenia associated with iMCD is rare. The association between iMCD and autoimmune neutropenia (AIN) involving anti‐neutrophil antibodies has not yet been elucidated.
Toshiki Morimoto, Takako Kawaguchi, Kei Yamasaki, Tatsuya Shingu, Hiroaki Ikegami, Hiroki Dosaka, Yuichi Murata, Yoshinori Kawabata, Kazuhiro Yatera   +8 more
wiley   +1 more source

Plasma Cell-rich Nephritis with a Systemic Polyclonal Lymphoproliferative Disorder, Mimicking Idiopathic Multicentric Castleman Disease, Systemic Lupus Erythematosus, and IgG4-related Disease. [PDF]

Intern Med
Idiopathic multicentric Castleman disease (iMCD), systemic lupus erythematosus (SLE), and IgG4-related disease (IgG4-RD) can cause lymphadenopathy with renal involvement.
Hebisawa Y, Ohta A, Sekimoto R, Sakurai N, Setoguchi K.   +4 more
europepmc   +2 more sources

Biomarkers and Signaling Pathways Implicated in the Pathogenesis of Idiopathic Multicentric Castleman Disease/Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis, Renal Insufficiency, and Organomegaly (TAFRO) Syndrome

Biomedicines
Idiopathic multicentric Castleman disease (iMCD) and TAFRO syndrome present a variety of symptoms thought to be caused by excessive inflammatory cytokines and chemokines, but the underlying mechanisms are unknown.
Remi Sumiyoshi, Tomohiro Koga, Atsushi Kawakami   +2 more
doaj   +1 more source