Results 151 to 160 of about 1,385 (194)

HHV-8-Negative, Idiopathic Multicentric Castleman Disease (iMCD): A Description of Clinical Features and Therapeutic Options through a Systematic Literature Review

Blood, 2014
Abstract Background: Multicentric Castleman disease (MCD) describes a heterogeneous group of poorly-understood diseases involving proinflammatory hypercytokinemia that ultimately results in systemic inflammatory symptoms, generalized lymphadenopathy, multiple organ system dysfunction, and even death.
David C Fajgenbaum   +7 more
openaire   +2 more sources

Burden of Idiopathic Multicentric Castleman Disease (iMCD) in the US: A Population-Level Real World Analysis Using a Health-Claims Dataset

Blood
Introduction: Idiopathic MCD (iMCD) is a rare non-neoplastic cytokine-driven disorder characterized by lymph node enlargement at multiple regions in the body. The epidemiology of iMCD remains poorly understood due to the rarity of the condition, diagnostic complexities and lack of population level registries in the
Ariela Noy   +9 more
openaire   +2 more sources

Lymph Node Transcriptomics in Idiopathic Multicentric Castleman Disease (iMCD) Identifies Pathogenic Mechanisms and Biomarkers Including Increased Clusterin Expression

Blood
Idiopathic multicentric Castleman disease (iMCD) is an atypical lymphoproliferative disorder with significant morbidity and mortality and a poorly understood pathophysiology. Defined by a characteristic lymph node (LN) histology, patients can present with a range of symptoms from thrombocytopenia, anasarca, fever ...
Michael V. Gonzalez   +7 more
openaire   +2 more sources

CLO23-049: An Unusual Case Presentation of Severe Idiopathic Multicentric Castleman Disease (iMCD)

Journal of the National Comprehensive Cancer Network, 2023
Himil Mahadevia   +3 more
openaire   +2 more sources

Idiopathic Multicentric Castleman’s Disease (iMCD)-TAFRO Syndrome with Atypical Renal Biopsy Findings

Journal of the American Society of Nephrology, 2023
Ciara L. Chen   +2 more
openaire   +2 more sources

From Castleman disease histopathological features to idiopathic multicentric Castleman disease: a multiparametric approach to exclude potential iMCD histopathological mimickers

Journal of Clinical Pathology, 2023
Aims International consensus diagnostic criteria for idiopathic multicentric Castleman disease (iMCD) includes lymph node Castleman disease (CD) histopathological features as major criteria. Our aim was to apply those criteria in a series of 42 cases with CD to find differences among unicentric CD, iMCD, HHV-8 ...
Laura Rodriguez Merino   +3 more
openaire   +2 more sources

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