Results 161 to 170 of about 1,385 (194)

877 | SPANISH IDIOPATHIC MULTICENTRIC CASTLEMAN DISEASE REGISTRY. EPIDEMIOLOGY OF IMCD IN SPAIN (ARCANA)—PREVALENCE COHORT

Hematological Oncology
J. T. Navarro Ferrando, A. Jiménez Ubieto, A. Rubio Martínez, A. Martín García‐Sancho, E. M. González Barca, P. Lorente Alegre, P. García Martín, G. Rodríguez, M. Espeso de Haro, A. M. Gutiérrez García, Á. Ramírez Payer, Í. Olazabal Eizaguirre, A. García, X. Cintas, A. González García, S. Montes Moreno   +15 more
openaire   +2 more sources

POS0380 SPANISH iMCD REGISTRY EPIDEMIOLOGY OF IDIOPATHIC MULTICENTRIC CASTLEMAN DISEASE IN SPAIN (ARCANA) - PREVALENCE COHORT

Annals of the Rheumatic Diseases
A. González García, P. Durán del Campo, R. Sánchez Martínez, J.T. Navarro, S. Montes-Moreno   +4 more
openaire   +2 more sources

Somatic mutation discovery in idiopathic multicentric castleman disease (iMCD) lymph node tissue identifies dysregulated intracellular calcium signaling as a potential disease mechanism and therapeutic target

Blood
Background: Idiopathic multicentric Castleman disease (iMCD) is a rare, atypical lymphoproliferative disorder with significant morbidity and mortality and unknown etiology.
Michael V. Gonzalez, Melanie D. Mumau, Joseph M. Zinski, Vikas Arige, Flore Castellan, Abiola Irvine, Katherine S. Forsyth, Ira D. Miller, Bridget Austin, C. Lavery, David Wu, David Yule, David B. Beck, D. Fajgenbaum   +13 more
semanticscholar   +1 more source

Retrospective real-world data analysis of morbidity burden and healthcare costs in idiopathic multicentric castleman disease compared with matched controls (BURDEN-iMCD)

Blood
Introduction: Idiopathic multicentric Castleman disease (iMCD) is a rare, cytokine-driven hematologic disorder characterized by diffuse lymphadenopathy and systemic inflammation.
A. Noy, R. Ohgami, N. Munshi, Imran Siddiqi, J. Cai, K. Dacus, Alicia Watson Saltis, F. Shupo, N. Princic, K. Evans, Sudipto Mukherjee   +10 more
semanticscholar   +1 more source

Prognostic value of serum C-reactive protein in idiopathic multicentric Castleman disease and construction of a prognostic model for patients

Frontiers in Medicine
Background Idiopathic Multicentric Castleman disease (iMCD) is a type of the rare lymphoproliferative diseases. C-reactive protein (CRP) is a well-recognized biomarker of inflammation, frequently exhibits elevated levels in individuals diagnosed with ...
Zhixiang Lei, Ya Wang, Tiantian Yu, Yiting Zhang, Wenting Cui, Cancan Luo, Qingqing Luo, Lili Zhou, Yuchen Gao, Li Yu   +9 more
semanticscholar   +1 more source

33 A Rare Case of Idiopathic Multicentric Castleman Disease with Ocular Involvement

American Journal of Clinical Pathology
Idiopathic multicentric Castleman disease (iMCD) is a benign lymphoproliferative disorder with uncertain etiology, as opposed to other forms such as Kaposi sarcoma-associated / human herpesvirus 8 (KSHV/HHV8)-associated multicentric Castleman ...
Alexander Yue, Daniel Ding
semanticscholar   +1 more source

Striking effectiveness of siltuximab-based treatment in refractory idiopathic multicentric Castleman disease resembling IgG4-related disease.

Journal of chemotherapy
Castleman disease (CD) and immunoglobulin G4-related disease (IgG4-RD) are rare systemic immune-mediated disorders that share similar clinical manifestations and overlapping pathological features. We present a case of insidious idiopathic multicentric CD
Xing Gong, Weiwei Yan, Feng Zhang, Dongdong Zhang   +3 more
semanticscholar   +1 more source

Increased type I interferon signaling is a hallmark of idiopathic multicentric castleman disease

Blood
Human herpesvirus (HHV)-8-negative, idiopathic multicentric Castleman disease (iMCD) is a rare hematologic illness involving progressive flares of inflammation, lymphoproliferation, and cytokine-induced organ failure. While there is an FDA-approved
Katherine S. Forsyth, Michael V. Gonzalez, Joseph M. Zinski, Melanie D. Mumau, D. Fajgenbaum   +4 more
semanticscholar   +1 more source

Idiopathic multicentric castleman disease - tafro: A potentially curable disease?

Blood
Idiopathic multicentric Castleman disease (iMCD) is a group of rare and sometimes life-threatening hematological disorders.The Castleman Disease Collaborative Network (CDCN) consensus for treating iMCD has been reached since 2018 and iMCD is ...
Lu Zhang, Jiaying Ge, Si-yuan Li, Liangshun You, Jian Li   +4 more
semanticscholar   +1 more source

Siltuximab-mediated suppression of CRP is associated with clinical response in idiopathic multicentric castleman disease

Blood
Introduction Idiopathic multicentric Castleman disease (iMCD) is a rare and serious disorder involving multicentric lymphadenopathy, systemic inflammation, and cytokine-driven organ dysfunction.
Jean-Franc¸ois Rossi, Azhaar Ashraf, Yildiz Kelahmetoglu, D. Fajgenbaum, Saishravan Shyamsundar, F. van Rhee   +5 more
semanticscholar   +1 more source