Results 11 to 20 of about 1,385 (194)

P911: SYMPTOM BURDEN AND ITS IMPACT ON DAILY LIFE AMONG PATIENTS WITH IDIOPATHIC MULTICENTRIC CASTLEMAN DISEASE (IMCD) – FINDINGS FROM AN INTERNATIONAL IMCD PATIENT SURVEY [PDF]

open access: yesHemasphere, 2022
Background: Background: Idiopathic Multicentric Castleman disease (iMCD) is a rare lymphoproliferative disorder driven by proinflammatory hypercytokinemia.
Shupo F   +8 more
europepmc   +4 more sources

Clinical Presentation, Treatment, and Outcomes of 28 Patients With Castleman Disease: A Retrospective Analysis of an Italian Cohort [PDF]

open access: yeseJHaem
Background Castleman disease (CD) encompasses a range of heterogeneous non‐clonal lymphoproliferative disorders, including unicentric (UCD), and multicentric (MCD) forms.
Caterina Cristinelli   +14 more
doaj   +3 more sources

Distinct interleukin-6 production in IPL and TAFRO subtypes of idiopathic multicentric Castleman disease [PDF]

open access: yesHaematologica
Idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disorder characterized by systemic inflammation and lymphadenopathy.
Asami Nishikori   +17 more
doaj   +4 more sources

TAFRO Syndrome Without Pathology Supporting Castleman Disease: To Be Treated as Idiopathic Multicentric Castleman Disease-TAFRO or a Distinct Disease Entity? [PDF]

open access: yesTurkish Journal of Hematology
Objective: TAFRO syndrome, entailing thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly, was previously considered a subtype of idiopathic multicentric Castleman disease (iMCD-TAFRO), with the diagnosis requiring pathology supporting
Siyuan Li   +4 more
doaj   +3 more sources

The Evolution and Recent Advances in Diagnostic Criteria for Idiopathic Multicentric Castleman Disease. [PDF]

open access: yesAm J Hematol
Idiopathic Multicentric Castleman Disease. ABSTRACT Idiopathic multicentric Castleman disease (iMCD) is a rare cytokine‐driven disorder characterized by systemic inflammation, organ dysfunction, and altered lymph node microscopic architecture. Over the past decade, diagnostic criteria have evolved significantly, integrating clinical, histopathological,
Alnoor F   +11 more
europepmc   +3 more sources

PS1403 IDIOPATHIC MULTICENTRIC CASTLEMAN DISEASE (IMCD) IN EUROPE: A HETEROGENEOUS DISEASE TREATED WITH A VARIETY OF AGENTS

open access: yesHemaSphere, 2019
Background:Idiopathic multicentric Castleman disease (iMCD) is a rare and heterogeneous plasmacytic lymphoproliferative disorder that involves multiple regions of lymphadenopathy and cytokine‐driven systemic inflammatory symptoms. Many patients experience life‐threatening multi‐organ failure.
C. Hoffmann   +13 more
openaire   +2 more sources

International Consensus Histopathological Criteria for Subtyping Idiopathic Multicentric Castleman Disease Based on Machine Learning Analysis. [PDF]

open access: yesAm J Hematol
ABSTRACT Idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disorder classified into three recognized clinical subtypes—idiopathic plasmacytic lymphadenopathy (IPL), TAFRO, and NOS. Although clinical criteria are available for subtyping, diagnostically challenging cases with overlapping histopathological features highlight ...
Nishimura MF   +14 more
europepmc   +3 more sources

Idiopathic Multicentric Castleman Disease With Severe Eosinophilia and Diffuse Centrilobular Nodule-A Rare Case Report. [PDF]

open access: yesCase Rep Hematol
Rationale Idiopathic multicentric Castleman disease (iMCD), also known as angiofollicular lymph node hyperplasia, is a rare inflammatory lymphoproliferative disease with diverse clinical presentations. We report a rare case of iMCD accompanied by severe eosinophilia and diffuse centrilobular pulmonary nodules, which have rarely been previously ...
Li X   +6 more
europepmc   +3 more sources

Exploring the Clinical Diversity of Castleman Disease and TAFRO Syndrome: A Japanese Multicenter Study on Lymph Node Distribution Patterns [PDF]

open access: yesAmerican Journal of Hematology, Volume 100, Issue 4, Page 592-605, April 2025.
Nagasaki University (長崎大学)博士(医学)Individuals diagnosed with Castleman disease (CD) and TAFRO syndrome (characterized by thrombocytopenia, anasarca, fever, bone marrow fibrosis, and organomegaly) displays a wide range of clinical symptoms, including ...
大塚, 瑞奈
core   +2 more sources

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