Results 21 to 30 of about 1,385 (194)

TAFRO syndrome requiring combined IL 6 and IL 1 inhibition: a case report [PDF]

Frontiers in Immunology
IntroductionTAFRO syndrome is a rare and severe variant of idiopathic multicentric Castleman disease (iMCD). The name-giving presentation is a combination of thrombocytopenia, anasarca, fever, reticulin fibrosis/renal dysfunction, and organomegaly.
Ahmad Wael Sultan, Eva Grießhammer, Carl Hinrichs, Lars Trenkmann, Ilske Oschlies, Leif Gunnar Hanitsch, Hildrun Haibel, Thomas Schneider, Rasmus Leistner   +8 more
doaj   +2 more sources

Reversible cerebral vasoconstriction syndrome in idiopathic multicentric Castleman disease under treatment with tocilizumab. [PDF]

BMJ Neurol Open
Background Idiopathic multicentric Castleman disease (iMCD) is a rare polyclonal lymphoproliferative disorder characterised by systemic inflammation resulting from overproduction of interleukin 6 (IL-6).
Kamimura N, Ueda N, Kimura K, Nishikori A, Sato Y, Kishida H, Tanaka F.   +6 more
europepmc   +3 more sources

Development and implementation of the International AIDA Network Castleman's disease registry. [PDF]

Front Med (Lausanne)
Castleman’s disease (CD) consists of a wide spectrum of rare disorders classified into unicentric CD and multicentric CD (MCD), based on the diffusion of disease distribution and the severity of clinical manifestations.
Vitale A, Sbalchiero J, Caggiano V, Lazzi S, Tharwat S, Fotis L, Lopalco G, Emmi G, Ruscitti P, Tufan A, Ragab G, Hissaria P, Dagna L, Wiesik-Szewczyk E, Hernández-Rodríguez J, González-Garcia A, Karamanakos A, Batu ED, Direskeneli H, Iannone F, Di Cola I, Kucuk H, Duran R, Saad MA, Ghanema M, Sikora M, Alibaz-Öner F, Beecher M, Ozen S, Cencini E, Bocchia M, Balistreri A, Fabiani C, Frediani B, Cantarini L, Zinzani P.   +35 more
europepmc   +5 more sources

PB2708: SYMPTOM BURDEN AND ITS IMPACT ON DAILY LIFE IN PATIENTS WITH IDIOPATHIC MULTICENTRIC CASTLEMAN’S DISEASE (IMCD): AN EXPLORATORY ANALYSIS OF THE SURVEY’S INTERNAL CONSTRUCT VALIDITY

HemaSphere, 2023
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Matt Franklin, Francis Shupo, Emily Jones, Nicola Mason, Grace Wayi-Wayi, Karan Kanhai, Natasa Zibelnick, Mileva Repasky, Kelly Makarounas-Kirchmann, Sudipto Mukherjee, John Brazier   +10 more
openaire   +3 more sources

Multicentric Castleman disease presenting with orbital involvement progressing to TAFRO syndrome: a case report [PDF]

BMC Ophthalmology
Background Castleman Disease (CD) can be unicentric or multicentric, with the ocular involvement rare; notably, the aggressive TAFRO syndrome (TS) is a subtype of idiopathic multicentric CD (iMCD). Ocular involvement in CD is rare, and to date, there are
Yuanfeng Wei, Jing Qi, Jiawei Yan, Guangjian Gao, Xinyue Ji, Danning Yu, Wanru Chen, Dongping Huang   +7 more
doaj   +2 more sources

Oligocentric Castleman disease: clinical characteristics and surgical outcomes from a single-centre retrospective study. [PDF]

Front Immunol
IntroductionOligocentric Castleman Disease (OCD), a distinct subtype of Castleman Disease (CD) intermediate between Unicentric (UCD) and idiopathic Multicentric (iMCD) forms, remains poorly characterised.MethodsThis study retrospectively analysed the ...
Duan Y, Gao X, Qian S, Hua R, Qiao H, Zhang S, Zong F, Li S, Song Y, Zhang M, Chen Q, Dong M, Zhang X.   +12 more
europepmc   +3 more sources

Cost-utility of siltuximab injection for idiopathic multicentric Castleman disease (iMCD) in China

Journal of Chinese Pharmaceutical Sciences, 2023
openaire   +2 more sources

LRG1, a novel serum biomarker for iMCD disease activity [PDF]

Biomarker Research
Idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disorder characterized by systematic inflammatory symptoms and multiorgan dysfunction caused by a cytokine storm.
Miao-yan Zhang, Zi-han Yang, Yu-chong Qiu, Yu-han Gao, Si-yuan Li, Yue Dang, Lu Zhang, Jian Li   +7 more
doaj   +2 more sources

Idiopathic multicentric Castleman disease in children: a single-center retrospective analysis

BMC Pediatrics
Objective To investigate the clinical features, pathological phenotype, treatment and prognosis of idiopathic multicenter Castleman disease (iMCD)in children. Methods From January 2017 to September 2023, basic information, laboratory tests, treatment and
Junye Du, Jiafeng Yao, Honghao Ma, Li Li, Ang Wei, Liping Zhang, Dong Wang, Zhigang Li, Rui Zhang, Tianyou Wang   +9 more
doaj   +2 more sources

No evidence for active viral infection in unicentric and idiopathic multicentric Castleman disease by Viral-Track analysis

Scientific Reports
Castleman disease (CD) is a rare hematologic disorder characterized by pathologic lymph node changes and a range of symptoms due to excessive cytokine production.
Ira Miller, Melanie D. Mumau, Saishravan Shyamsundar, Mateo Sarmiento Bustamante, Pedro Horna, Michael V. Gonzalez, David C. Fajgenbaum   +6 more
doaj   +2 more sources