Validated international definition of the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype (TAFRO) of idiopathic multicentric Castleman disease [PDF]
, 2021 Thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly (TAFRO) syndrome is a heterogeneous entity manifesting with a constellation of symptoms described above that can occur in the context of idiopathic multicentric ...
Fajgenbaum, David C. +15 more
core +1 more source
Idiopathic Multicentric Castleman Disease following SARS-CoV-2 Vaccination
Journal of Cancer Research and Practice, 2023 Idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disorder. The preferred primary treatment for iMCD is siltuximab, an anti-interleukin-6 antibody (anti–IL-6).
Chien-Yu Ker +3 more
doaj +1 more source
Idiopathic multicentric Castleman disease treated with siltuximab for 15 years: a case report
Therapeutic Advances in Hematology, 2022 Human herpes virus-8 (HHV8)-negative, idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disorder sustained by pro-inflammatory cytokines, including interleukin-6 (IL-6).
Evan Lang +3 more
doaj +1 more source
The clinical, laboratory, and radiologic improvement due to siltuximab treatment in idiopathic multicentric Castleman’s disease [PDF]
The Korean Journal of Internal Medicine, 2021 Background/Aims Idiopathic multicentric Castleman disease (iMCD) comprises approximately 30% of all cases of Castleman disease. It is characterized by constitutional symptoms, enlarged lymph nodes at multiple anatomical sites, and laboratory test ...
Gi-June Min +16 more
doaj +1 more source
Journal of Cancer Research and Practice, 2023 TAFRO syndrome, or now formally termed idiopathic multicentric Castleman disease (iMCD) with thrombocytopenia, anasarca, fever, renal insufficiency or reticulin fibrosis, and organomegaly (iMCD-TAFRO), describes a unique subtype of iMCD.
Pei-An Fu, Chia-Chi Wu, Ya-Ting Hsu
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Idiopathic multicentric Castleman disease presenting progressive reticular honeycomb infiltration of lung and immunoglobulin G and immunoglobulin G4 dominant hypergammaglobulinemia: a case report [PDF]
Journal of Yeungnam Medical Science, 2022 Multicentric Castleman disease (MCD) is an uncommon systemic lymphoproliferative disorder that may cause multiple organ damage. Castleman disease-associated diffuse parenchymal lung disease (DPLD) has not been well studied. A 32-year-old man was referred
Hyun-Je Kim, Young-Hoon Hong
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Diagnostics, 2022 Background: POEMS syndrome (POEMS) is a rare plasma cell clonal paraneoplastic syndrome consisting of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes presenting with idiopathic multicentric Castleman disease (iMCD ...
Yong-Moon Lee +2 more
doaj +1 more source
Idiopathic multicentric Castleman disease: pathogenesis, clinical presentation and recommendations for treatment based on the Castleman Disease Collaborative Network (CDCN) [PDF]
, 2021 Castleman disease is a very rare, lymphoproliferative disease, driven by dysregulation of the cytokine interleukin 6 (IL-6) and other proinflammatory cytokines with the development of symptoms of systemic inflammation, reactive proliferation of ...
Domańska-Czyż, Katarzyna +3 more
core +2 more sources
eJHaem, 2022 Idiopathic multicentric Castleman disease (iMCD) is a lymphoproliferative disease of unknown etiology. Deciphering mechanisms involved in CD pathogenesis may help improving patients’ care.
Thomas Ballul +20 more
doaj +1 more source
Case Reports in Oncology, 2021 TAFRO syndrome is defined by the presence of thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis/renal dysfunction (R), and organomegaly (O) and can be seen with idiopathic multicentric Castleman disease (iMCD) or as an isolated process ...
Corinne Williams +5 more
doaj +1 more source