Results 61 to 70 of about 1,385 (194)

Idiopathic multicentric Castleman disease resembling autoimmune diseases: A case report. [PDF]

Medicine (Baltimore)
Rationale: Castleman disease (CD) is a rare lymphoproliferative disorder characterized by nonmalignant lymph node enlargement, often associated with systemic symptoms.
Li T, Yao M, Hou Y.
europepmc   +2 more sources

Complications and Management of Idiopathic Multicentric Castleman Disease. [PDF]

HCA Healthc J Med
Background The pathophysiology of idiopathic multicentric Castleman disease (iMCD) is poorly understood compared to the other subtypes of MCD, which has contributed to limited treatment options and poor prognosis for iMCD patients.
Feustel K, Keeling J, Makos O, Scherbak D.   +3 more
europepmc   +2 more sources

TAFRO syndrome: New subtype of idiopathic multicentric Castleman disease [PDF]

, 2017
Castleman disease (CD) describes a group of three rare and poorly understood lymphoproliferative disorders that have heterogeneous clinical symptoms and common lymph node histopathological features.
David C Fajgenbaum, Gordan Srkalovic, Inga Marijanovic, Maya B Srkalovic   +3 more
core   +2 more sources

Long-term remission in idiopathic Castleman's disease with tocilizumab followed by consolidation with high-dose melphalan-two case studies. [PDF]

, 2015
Multicentric Castleman's disease (MCD) is an uncommon lymphoproliferative disorder, often associated with a clinically aggressive behavior. No standard treatment has been established, but patients are usually treated with lymphoma-type regimens such as ...
Castleman, Fajgenbaum, Ganti, Gerard, Menke, Nishimoto, Ogita, Repetto, Rhee, Szturz, Zhu   +10 more
core   +3 more sources

Unmet Clinical Needs in the Management of Idiopathic Multicentric Castleman Disease: A Consensus-based Position Paper From an ad hoc Expert Panel

HemaSphere, 2023
Castleman disease describes a group of heterogeneous clinicopathological disorders now included in the tumor-like lesions with B-cell predominance of the World Health Organization classification.
Pier Luigi Zinzani, Marco Paulli, Luca Arcaini, Emanuel Della Torre, Simone Ferrero, Amalia Figuera, Ferdinando Frigeri, Maurizio Martelli, Elena Sabattini, Riccardo Scarpa, Giovanni Barosi   +10 more
doaj   +1 more source

Idiopathic Multicentric Castleman Disease with Strikingly Elevated IgG4 Concentration in the Serum and Abundant IgG4-Positive Cells in the Tissue: A Case Report

Diagnostics, 2022
Idiopathic multicentric Castleman disease (iMCD) can be challenging to distinguish clinically and histopathologically from Immunoglobulin G4-related disease (IgG4RD).
Chia-Chun Cheng, Ying-Chu Chen, Yung-Hsiang Hsu, Kuei-Ying Su   +3 more
doaj   +1 more source

A Phase Ib Investigator-Initiated Trial of Filgotinib in Patients With Idiopathic Multicentric Castleman Disease. [PDF]

Cureus
Background Idiopathic multicentric Castleman disease (iMCD) is a chronic systemic inflammatory disease characterized by the production of interleukin (IL)-6.
Fukui S, Sumiyoshi R, Koga T, Hosogaya N, Narita S, Morimoto S, Yano H, Katsube A, Yano S, Masaki Y, Tsunoda S, Sato S, Migita K, Matsuyama K, Kato N, Kawamoto A, Kawakami A.   +16 more
europepmc   +2 more sources

Idiopathic multicentric Castleman’s disease, infrequent cause of Lupus-like. Case Report. [PDF]

, 2019
Castleman’s disease (CD) or angiofollicular lymph node hyperplasia includes a heterogeneous mix of reactive lymphoproliferative processes with well-defined histological features.
Cabezas, Antonio Fabian, Lillo, Fernando Andrés, Riquelme, Santiago Felipe Andrés, Zapata, Juan Manuel   +3 more
core   +2 more sources

Rare disease research requires (and benefits from) global collaboration: three examples from the Castleman Disease Collaborative Network [PDF]

, 2016
Castleman disease (CD) describes a heterogeneous group of rare and poorly understood lymphoproliferative disorders that can involve flu-like symptoms, multiple organ system dysfunction, and even death.
Ahagon, Deise, Croglio, Michael, Enciso, Auryn, Fajgenbaum, David, Jayanthan, Raj, Liu, Amy Yutong, Mitchell, Grant, Newman, Samantha Kass, Ruth, Jason, Suarez, Alexander, Williamson, Hayley, Zhen, Emily   +11 more
core   +2 more sources

Lymphadenopathy in the rheumatology practice: a pragmatic approach [PDF]

, 2023
Lymphadenopathy is a common clinical finding and diagnostic challenge within general medicine and rheumatology practice. It may represent a primary manifestation of an underlying immune-mediated disease or indicate an infectious or neoplastic ...
Bongiovanni, Lucia, Della-Torre, Emanuel, Fajgenbaum, David C, Mehta, Puja, Rodolfi, Stefano, Selmi, Carlo   +5 more
core