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Redefining Idiopathic Normal Pressure Hydrocephalus Using AI-Driven Brain Volumetry [PDF]

Biomedicines
Idiopathic normal pressure hydrocephalus (iNPH) is a potentially reversible cause of gait disturbance and cognitive impairment in older adults, yet its diagnosis remains challenging and controversial.
Juan Sahuquillo, Murad Al-Nusaif, Aasma Sahuquillo-Muxi, Paula Duch, Maria-Antonia Poca, on behalf of the Alzheimer’s Disease Neuroimaging Initiative   +5 more
doaj   +2 more sources

Characteristics of Postural Instability in Idiopathic Normal Pressure Hydrocephalus [PDF]

Neurology and Therapy
Introduction In patients with idiopathic normal pressure hydrocephalus (iNPH), the characteristics of static steady-state balance disturbance are not as well understood as those related to gait.
Eunhee Park, Kyunghun Kang, Janghoon Lee, Jong Taek Lee, Ki-Su Park, Chul-Hyun Kim, Yu-Sun Min   +6 more
doaj   +2 more sources

Knowledge of idiopathic normal pressure hydrocephalus among healthcare professionals [PDF]

Scientific Reports
Idiopathic normal pressure hydrocephalus (iNPH) is a prevalent, yet greatly underdiagnosed condition in older adults, which can cause significant disability if left untreated.
Rocío Fernández-Méndez, Toby Meek, Benjamin Dias-Dougan, Lisa Healy, Indu Lawes, Andrew H.D. Wynd, John D. Pickard, Mathew R. Garnett, Peter Smielewski, Alexis J. Joannides   +9 more
doaj   +2 more sources

Distinct cerebral cortical microstructural changes in idiopathic normal-pressure hydrocephalus [PDF]

Frontiers in Neurology
ObjectiveThe aims of the study were to investigate differences in cortical mean diffusivity (MD) among idiopathic normal-pressure hydrocephalus (INPH) patients, Alzheimer’s disease (AD) patients, and healthy controls, and to analyze mean MD among INPH ...
Myong Hun Hahm, Shin Young Jeong, Suhyun Kim, Sang-Woo Lee, Ki-Su Park, Eunhee Park, Mi-Yeon Eun, Uicheul Yoon, Kyunghun Kang   +8 more
doaj   +2 more sources

Clinical characteristics and outcomes after shunt surgery in idiopathic normal pressure hydrocephalus with or without prior cerebrospinal fluid tap testing: a single-center follow-up study of 481 patients [PDF]

Fluids and Barriers of the CNS
Background The cerebrospinal fluid tap test (CSF TT) is a commonly used predictive test for selecting patients with idiopathic normal pressure hydrocephalus (iNPH) for shunt surgery, but low sensitivity rate carries the risk of excluding individuals from
Kardelen Akar, Lena Kollen, Hanna C. Persson, Mats Tullberg   +3 more
doaj   +2 more sources

Clinical tips in diagnosing idiopathic normal pressure hydrocephalus: a new concept beyond the cerebrospinal fluid tap test [PDF]

Journal of Integrative Neuroscience, 2021
Accurate diagnosis of idiopathic normal pressure hydrocephalus is important to manage patients with idiopathic normal pressure hydrocephalus more appropriately.
Seon-Min Lee, Kyum-Yil Kwon   +1 more
doaj   +1 more source

Beyond pressure: intracranial compliance and retinal biomarkers in idiopathic normal pressure hydrocephalus [PDF]

Frontiers in Neurology
Mathias Just Nortvig, Mathias Just Nortvig, Niclas Lynge Eriksen, Niclas Lynge Eriksen, Jan Saip Aunan-Diop, Jan Saip Aunan-Diop, Bjarni Johannsson, Bjarni Johannsson, Dag Ferner Netteland, Dag Ferner Netteland, Christian Bonde Pedersen, Christian Bonde Pedersen, Sune Munthe, Sune Munthe, Frantz Rom Poulsen, Frantz Rom Poulsen   +15 more
doaj   +2 more sources

Lumbar-peritoneal shunt for idiopathic normal pressure hydrocephalus and secondary normal pressure hydrocephalus

Tzu Chi Medical Journal, 2022
Objectives: Normal-pressure hydrocephalus is a clinical syndrome consisting of dilated cerebral ventricles with the clinical triad of gait disturbance, cognitive impairment and/or urinary dysfunction. Lumbar-peritoneal (LP) shunt could improve idiopathic
Chia-Lin Liao, Pao-Hui Tseng, Hsin-Yi Huang, Tsung-Lang Chiu, Shinn-Zong Lin, Sheng-Tzung Tsai   +5 more
doaj   +1 more source

Ten Steps for NPH Management: Advancements in Diagnosis and Treatment of Adult Hydrocephalus

Brazilian Neurosurgery, 2023
Objectives The authors of the present study intend to describe a straightforward protocol for normal pressure hydrocephalus diagnosis and management, with the employment of a multidisciplinary team approach effort.
Alex Roman, Prince Takkar, Tanmoy Maiti
doaj   +1 more source

Progressive cognitive impairment evolving to dementia parallels parieto-occipital and temporal enlargement in idiopathic chronic hydrocephalus: a retrospective cohort study [PDF]

, 2015
Little is known regarding progressive enlargement of the ventricular system in symptomatic patients or asymptomatic subjects. Before eventual surgical treatment, we evaluated the clinical and radiological features of an extremely rare group of patients ...
CURRA', antonio, MISSORI, Paolo
core   +6 more sources