Results 41 to 50 of about 13,037 (197)

Current research of idiopathic normal pressure hydrocephalus: Pathogenesis, diagnosis and treatment

World Journal of Clinical Cases, 2023
Idiopathic normal pressure hydrocephalus (iNPH) is caused by impaired cerebrospinal fluid absorption in the elderly; it is a surgically treatable form of dementia. Gait disturbance, dementia, and urinary incontinence are the triad of signs for iNPH.
T. Ishida, Tomonori Murayama, Seiju Kobayashi   +2 more
semanticscholar   +1 more source

Higher prevalence of idiopathic normal pressure hydrocephalus‐like MRI features in progressive supranuclear palsy: An imaging reminder of atypical parkinsonism

Brain and Behavior, 2023
The classic triad of idiopathic normal pressure hydrocephalus (NPH) encompass gait disturbance, cognitive impairment, and urinary incontinence. These symptoms overlap with parkinsonism but with distinct treatment.
M. Fu, Chih-Cheng Huang, Kay L. H. Wu, Ying-Fa Chen, Y. Kung, Chen-Chang Lee, Jia-Shou Liu, M. Lan, Yung-Yee Chang   +8 more
semanticscholar   +1 more source

Current updates on idiopathic normal pressure hydrocephalus

Asian Journal of Neurosurgery, 2019
Idiopathic normal pressure hydrocephalus (iNPH) is one of the neurodegenerative diseases which can be treated surgically with favorable outcome. The gait disturbance, cognitive, and urinary symptoms are known as the clinical triad of iNPH. In this review, we have addressed the comorbidities, differential diagnoses, clinical presentations, and pathology
Liew, Boon Seng, Takagi, Kiyoshi, Kato, Yoko, Duvuru, Shyam, Thanapal, Sengottuvel, Mangaleswaran, Balamurugan   +5 more
openaire   +3 more sources

Tightened sulci in the high convexities as a noteworthy feature of idiopathic normal pressure hydrocephalus.

World Neurosurgery, 2023
OBJECTIVE The presence of tightened sulci in the high-convexities (THC) is a key morphological feature for the diagnosis of idiopathic normal pressure hydrocephalus (iNPH), but the exact localization of THC has yet to be defined.
Shigeki Yamada, H. Ito, Hironori Matsumasa, M. Tanikawa, Satoshi Ii, T. Otani, S. Wada, M. Oshima, Yoshiyuki Watanabe, M. Mase   +9 more
semanticscholar   +1 more source

Cerebrospinal fluid biomarkers that reflect clinical symptoms in idiopathic normal pressure hydrocephalus patients

Fluids and Barriers of the CNS, 2022
Background The relationship between cerebrospinal fluid (CSF) biomarkers and the clinical features of idiopathic normal pressure hydrocephalus (iNPH) has been inconclusive.
Heikki Lukkarinen, Anna Jeppsson, Carsten Wikkelsö, Kaj Blennow, Henrik Zetterberg, Radu Constantinescu, Anne M. Remes, Sanna-Kaisa Herukka, Mikko Hiltunen, Tuomas Rauramaa, Katarina Nägga, Ville Leinonen, Mats Tullberg   +12 more
doaj   +1 more source

Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus

Fluids and Barriers of the CNS, 2023
Background Idiopathic Normal pressure hydrocephalus (iNPH) is a form of adult hydrocephalus that is clinically characterized by progressive gait impairment, cognitive dysfunction, and urinary incontinence.
Sophia Weiner, A. Junkkari, Mathias Sauer, A. Luikku, T. Rauramaa, T. Kokkola, S. Herukka, K. Blennow, H. Zetterberg, V. Leinonen, J. Gobom   +10 more
semanticscholar   +1 more source

Altered glymphatic system in idiopathic normal pressure hydrocephalus.

Parkinsonism & Related Disorders, 2020
OBJECTIVE To assess the glymphatic activity in patients with idiopathic normal pressure hydrocephalus (NPH) using the "Diffusion Tensor Image-Analysis aLong the Perivascular Space (DTI-ALPS)" method, and determine the feasibility of non-invasive MRI for ...
Y. J. Bae, B. Choi, Jong-Min Kim, Ji-Hyun Choi, Se Jin Cho, Jae Hyoung Kim   +5 more
semanticscholar   +1 more source

Intrathecal Contrast-Enhanced Magnetic Resonance Imaging of Cerebrospinal Fluid Dynamics and Glymphatic Enhancement in Idiopathic Normal Pressure Hydrocephalus

Frontiers in Neurology, 2022
Idiopathic normal pressure hydrocephalus (iNPH) is a neurodegenerative disease, characterized by cerebrospinal fluid (CSF) flow disturbance. Today, the only available treatment is CSF diversion surgery (shunt surgery).
P. Eide, A. Lashkarivand, Åsmund Aleksander Hagen-Kersten, Ø. Gjertsen, B. Nedregaard, Ruth O. Sletteberg, Grethe Løvland, S. Vatnehol, A. Pripp, L. Valnes, G. Ringstad   +10 more
semanticscholar   +1 more source

Normal-pressure hydrocephalus: A critical review

Dementia & Neuropsychologia, 2019
. Normal-pressure hydrocephalus (NPH) is a potentially reversible syndrome characterized by enlarged cerebral ventricles (ventriculomegaly), cognitive impairment, gait apraxia and urinary incontinence.
Louise Makarem Oliveira, Ricardo Nitrini, Gustavo C. Román   +2 more
doaj   +1 more source

Pathophysiological Mechanisms Underlying Idiopathic Normal Pressure Hydrocephalus: A Review of Recent Insights

Frontiers in Aging Neuroscience, 2022
The pathophysiologic mechanisms underpinning idiopathic normal pressure hydrocephalus (iNPH), a clinically diagnosed dementia-causing disorder, continue to be explored.
P. Bonney, Robert G. Briggs, Kevin Wu, Woo-Yeon Choi, Anadjeet S Khahera, Brandon Ojogho, Xingfeng Shao, Z. Zhao, Matthew Borzage, Danny J. J. Wang, Charles Liu, Darrin J. Lee   +11 more
semanticscholar   +1 more source