Results 21 to 30 of about 7,558 (162)

Deletions in CWH43 cause idiopathic normal pressure hydrocephalus

EMBO Molecular Medicine, 2021
Idiopathic normal pressure hydrocephalus (iNPH) is a neurological disorder that occurs in about 1% of individuals over age 60 and is characterized by enlarged cerebral ventricles, gait difficulty, incontinence, and cognitive decline.
Hong Wei Yang, Semin Lee, Dejun Yang, Huijun Dai, Yan Zhang, Lei Han, Sijun Zhao, Shuo Zhang, Yan Ma, Marciana F Johnson, Anna K Rattray, Tatyana A Johnson, George Wang, Shaokuan Zheng, Rona S Carroll, Peter J Park, Mark D Johnson   +16 more
doaj   +1 more source

Imaging Markers for Normal Pressure Hydrocephalus: An Overview

Biomedicines, 2023
Idiopathic bormal pressure hydrocephalus (iNPH) is a neurological syndrome that clinically presents with Hakim’s triad, namely cognitive impairment, gait disturbances, and urinary incontinence.
Efstratios-Stylianos Pyrgelis, Georgios Velonakis, Sokratis G. Papageorgiou, Leonidas Stefanis, Elisabeth Kapaki, Vasilios C. Constantinides   +5 more
doaj   +1 more source

Idiopathic Normal Pressure Hydrocephalus, Case Series [PDF]

Pan Arab Journal of Neurosurgery
Introduction:Idiopathic normal pressure hydrocephalus (iNPH) was first described by Dr Hakim and Dr. Adam on1964 in case series described triad of symptoms of difficult walking, dementia and urine incontinence.
Ahmed Elshanawany, Ahmed Elgheriany, Farrag Mohammad   +2 more
doaj   +1 more source

Levels of selected pro- and anti-inflammatory cytokines in cerebrospinal fluid in patients with hydrocephalus

Folia Neuropathologica, 2017
Cytokines are widely known mediators of inflammation accompanying many neurodegenerative disorders including normal pressure hydrocephalus (NPH). NPH is caused by impaired cerebrospinal fluid (CSF) absorption and treated by surgical shunt insertion.
Kinga Czubowicz, Mariusz Głowacki, Ewa Fersten, Ewa Kozłowska, Robert P. Strosznajder, Zbigniew Czernicki   +5 more
doaj   +1 more source

Current updates on idiopathic normal pressure hydrocephalus

Asian Journal of Neurosurgery, 2019
Idiopathic normal pressure hydrocephalus (iNPH) is one of the neurodegenerative diseases which can be treated surgically with favorable outcome. The gait disturbance, cognitive, and urinary symptoms are known as the clinical triad of iNPH. In this review, we have addressed the comorbidities, differential diagnoses, clinical presentations, and pathology
Liew, Boon Seng, Takagi, Kiyoshi, Kato, Yoko, Duvuru, Shyam, Thanapal, Sengottuvel, Mangaleswaran, Balamurugan   +5 more
openaire   +3 more sources

Cognitive Profile of Idiopathic Normal Pressure Hydrocephalus

Dementia and Geriatric Cognitive Disorders Extra, 2011
Background/Aims: Frontal lobe dysfunction is believed to be a primary cognitive symptom in idiopathic normal pressure hydrocephalus (iNPH); however, the neuropsychology of this disorder remains to be fully investigated. The objective of this study was to
Makoto Saito, Yoshiyuki Nishio, Shigenori Kanno, Makoto Uchiyama, Akiko Hayashi, Masahito Takagi, Hirokazu Kikuchi, Hiroshi Yamasaki, Tatsuo Shimomura, Osamu Iizuka, Etsuro Mori   +10 more
doaj   +1 more source

Cerebrospinal fluid biomarkers that reflect clinical symptoms in idiopathic normal pressure hydrocephalus patients

Fluids and Barriers of the CNS, 2022
Background The relationship between cerebrospinal fluid (CSF) biomarkers and the clinical features of idiopathic normal pressure hydrocephalus (iNPH) has been inconclusive.
Heikki Lukkarinen, Anna Jeppsson, Carsten Wikkelsö, Kaj Blennow, Henrik Zetterberg, Radu Constantinescu, Anne M. Remes, Sanna-Kaisa Herukka, Mikko Hiltunen, Tuomas Rauramaa, Katarina Nägga, Ville Leinonen, Mats Tullberg   +12 more
doaj   +1 more source

Endoscopic third ventriculostomy in idiopathic normal pressure hydrocephalus

Alexandria Journal of Medicine, 2014
Objective: To determine the efficacy of endoscopic fenestration of the third ventricle in the treatment of idiopathic normal pressure hydrocephalus.
Mohammed Ahmed Eshra
doaj   +1 more source

Shunting for Idiopathic Normal-Pressure Hydrocephalus

New England Journal of Medicine
Normal pressure hydrocephalus (NPH) occurs when the brain ventricles expand, causing a triad of gait, cognitive, and urinary impairment. It can occur after a clear brain injury such as trauma, but can also occur without a clear cause (termed idiopathic, or iNPH). Non-randomised studies have shown a benefit from surgically diverting ventricular fluid to
Ronald, P, Gontsarova, A, Richardson, D, Methley, AM, Watt, HC, Tsang, K, Carswell, C   +6 more
openaire   +7 more sources

Normal-pressure hydrocephalus: A critical review

Dementia & Neuropsychologia, 2019
. Normal-pressure hydrocephalus (NPH) is a potentially reversible syndrome characterized by enlarged cerebral ventricles (ventriculomegaly), cognitive impairment, gait apraxia and urinary incontinence.
Louise Makarem Oliveira, Ricardo Nitrini, Gustavo C. Román   +2 more
doaj   +1 more source