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Idiopathic Normal Pressure Hydrocephalus
Tijdschrift voor psychiatrie, 2018Hydrocephalus is characterized by overaccumulation of cerebrospinal fluid (CSF) within the cerebral ventricles due to a mismatch between CSF production and CSF resorption into systemic circulation [1]. While many forms of hydrocephalus are associated with raised intracranial pressure (ICP) [2, 3], some patients have clinical and radiologic signs of ...
Albert M. Isaacs +2 more
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[Idiopathic normal pressure hydrocephalus].
No shinkei geka. Neurological surgery, 2013This observational study aimed to explore the pathophysiology of idiopathic normal-pressure hydrocephalus (iNPH) and to evaluate the diagnostic and prognostic value of CSF biomarkers.Lumbar CSF of patients with iNPH and healthy elderly individuals (HI) and ventricular CSF (VCSF) from the patients with iNPH pre and 6 months postsurgery were analyzed by ...
Hajime, Arai +2 more
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Idiopathic Normal Pressure Hydrocephalus
2012Idiopathic normal pressure hydrocephalus (INPH) is characterized by the clinical triad of gait disturbance, cognitive dysfunction, and urinary symptoms, observed in the context of enlargement of the cerebral ventricular system. Mean age of onset is approximately 60 years, which complicates the diagnosis since there is the potential for multiple age ...
Lisa D. Ravdin, Heather L. Katzen
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Idiopathic Normal Pressure Hydrocephalus
Neurosurgery Quarterly, 2011The syndrome of idiopathic normal pressure hydro- cephalus was first described in 1965, but 45 years later controversies still exist with regard to its cause, progression, differential diagnosis, and best treatment strategies. Its incidence may be underestimated and its importance increasing because of the aging population.
Andrew Tarnaris, Michael A. Williams
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Idiopathic normal pressure hydrocephalus and systemic hypertension
Neurology, 1987Nineteen patients with idiopathic normal pressure hydrocephalus (NPH) were treated with intraventricular shunts. Ten of the 14 who improved and 14 of the total group had systemic hypertension. The prevalence of hypertension in both the improved and whole NPH groups was significantly greater than in a control group with dementia (N = 122) and the ...
N R, Graff-Radford, J C, Godersky
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Familial Occurrence of Idiopathic Normal-Pressure Hydrocephalus
Archives of Neurology, 1984Shunt-responsive normal-pressure hydrocephalus developed in a 67-year-old man and in his 74-year-old sister. To our knowledge, a familial association in this disorder has not been reported previously.
R K, Portenoy, A, Berger, E, Gross
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[Idiopathic normal pressure hydrocephalus].
Praxis, 2009Normal pressure hydrocephalus (NPH) is characterized by the classic triad of symptoms including gait disturbance, urinary incontinence, and dementia. Gait impairment represents the cardinal symptom. NPH is associated with a radiological verifiable ventriculomegaly in the absence of elevated cerebrospinal fluid (CSF) pressure.
O P, Gautschi +4 more
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A Glycan Marker for Idiopathic Normal Pressure Hydrocephalus
2014Two glycan isoforms of transferrin (Tf), Tf-1 and Tf-2, were found in cerebrospinal fluid (CSF). Tf-1 concentration in CSF was reduced in idiopathic normal pressure hydrocephalus (iNPH), an elderly dementia caused by abnormal metabolism of CSF, whereas Tf-2 concentration was not. The reduction of Tf-1 concentration was not found in Alzheimer’s disease,
Kyoka Hoshi +13 more
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Idiopathic Normal Pressure Hydrocephalus
Contemporary Neurosurgery, 2014Saul F. Morales-Valero +2 more
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The “Reversible” Dementia of Idiopathic Normal Pressure Hydrocephalus
The Consultant Pharmacist, 2006Unstable gait, urinary incontinence, confusion. Most health care practitioners, including consultant pharmacists, immediately associate these problems with the signs and symptoms of vascular or Alzheimer's dementia. But, there also exists a small population of patients for whom these signs and symptoms are related to another-often curable-problem ...
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