Discovery of Novel CSF Clearance Mechanism of Idiopathic Normal Pressure Hydrocephalus and Alzheimer's Disease [PDF]
Abstract Background In idiopathic normal pressure hydrocephalus (iNPH) and Alzheimer's disease (AD), clearance of cerebrospinal fluid (CSF) is impaired, leading to the buildup of harmful proteins and metabolic waste in the brain, contributing to disease pathology. A significant number of iNPH patients have AD as a comorbidity, and both diseases display
Lipponen A +6 more
europepmc +2 more sources
Characterization of lower urinary tract symptoms in patients with idiopathic normal pressure hydrocephalus [PDF]
AIMS: The purpose of this study was to evaluate lower urinary tract symptoms (LUTS) in idiopathic normal pressure hydrocephalus (iNPH). METHODS: Patients with new-onset iNPH were prospectively evaluated for LUTS via detailed history and physical, and ...
Ahlberg +25 more
core +2 more sources
Imaging Markers for Normal Pressure Hydrocephalus: An Overview
Idiopathic bormal pressure hydrocephalus (iNPH) is a neurological syndrome that clinically presents with Hakim’s triad, namely cognitive impairment, gait disturbances, and urinary incontinence.
Efstratios-Stylianos Pyrgelis +5 more
doaj +1 more source
Clinical Features of Pediatric Idiopathic Intracranial Hypertension and Applicability of New ICHD-3 Criteria [PDF]
Idiopathic intracranial hypertension (IIH) is characterized by intracranial pressure >28 cmH2O in the absence of identifiable causes. Aim of this paper is to describe the clinical phenotype of pediatric IIH and to analyze the applicability of ICHD-3 ...
Barbara Battan +8 more
core +2 more sources
The APOE Genotype in Idiopathic Normal Pressure Hydrocephalus. [PDF]
Amyloid plaque has been reported in brain biopsies from patients with idiopathic normal-pressure hydrocephalus (iNPH) and proposed as a significant feature of the pathophysiology.
Yi Yang +6 more
doaj +1 more source
Cytokines are widely known mediators of inflammation accompanying many neurodegenerative disorders including normal pressure hydrocephalus (NPH). NPH is caused by impaired cerebrospinal fluid (CSF) absorption and treated by surgical shunt insertion.
Kinga Czubowicz +5 more
doaj +1 more source
Pseudotumor cerebri syndrome in childhood : incidence, clinical profile and risk factors in a national prospective population-based cohort study [PDF]
Aim To investigate the epidemiology, clinical profile and risk factors of pseudotumor cerebri syndrome (PTCS) in children aged 1-16 years. Methods A national prospective population-based cohort study over 25 months.
Dean, Fiona +8 more
core +3 more sources
Idiopaatiline normaalrõhu hüdrotsefaalia. Ülevaade ja haigusjuhu kirjeldus [PDF]
Idiopaatiline normaalrõhu hüdrotsefaalia ( INRH) on sündroom, mille korral on täheldatav aju külgvatsakeste ning osal juhtudel ka kolmanda vatsakese suurenemine. Selline olukord kujuneb normaalse intrakraniaalse rõhu ja mehaaniliselt vabade liikvoriteede
Eelmäe, Jaan, Kõiv, Kennet
core +2 more sources
Background The relationship between cerebrospinal fluid (CSF) biomarkers and the clinical features of idiopathic normal pressure hydrocephalus (iNPH) has been inconclusive.
Heikki Lukkarinen +12 more
doaj +1 more source
Prevalence of idiopathic normal-pressure hydrocephalus [PDF]
The aim of this study was to determine the prevalence of idiopathic normal-pressure hydrocephalus (iNPH) in elderly persons in a large population-based sample using radiologic and clinical examinations.We examined representative elderly populations aged 70 years and older that had undergone neuropsychiatric evaluations and CT of the brain between 1986 ...
Daniel, Jaraj +5 more
openaire +2 more sources

