Results 1 to 10 of about 69,231 (100)

Common idiopathic pulmonary fibrosis risk variants are associated with hypersensitivity pneumonitis [PDF]

, 2021
A subset of patients with hypersensitivity pneumonitis (HP) develop lung fibrosis that is clinically similar to idiopathic pulmonary fibrosis (IPF). To address the aetiological determinants of fibrotic HP, we investigated whether the common IPF genetic ...
Lee, Joyce S, Peljto, Anna, Molyneaux, Philip, Fernández Pérez, Evans, Wolters, Paul, Schwartz, David A, Cardwell, Jonathan, Yang, Ivana V, Yang, Ivana, Lee, Joyce, Walts, Avram, Peljto, Anna L, Molyneaux, Philip L, Furusawa, Haruhiko, Schwartz, David, Wolters, Paul J, Fernández Pérez, Evans R, Walts, Avram D   +17 more
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Lung Cancer in Pulmonary Fibrosis: Tales of Epithelial Cell Plasticity [PDF]

, 2011
Lung epithelial cells exhibit a high degree of plasticity. Alterations to lung epithelial cell function are critically involved in several chronic lung diseases such as pulmonary fibrosis.
Königshoff, M., Melanie Königshoff, Königshoff, Melanie   +2 more
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Association of FcγRIIa R131H polymorphism with idiopathic pulmonary fibrosis severity and progression [PDF]

, 2010
Background A significant genetic component has been described for idiopathic pulmonary fibrosis (IPF). The R131H (rs1801274) polymorphism of the IgG receptor FcγRIIa determines receptor affinity for IgG subclasses and is associated with several chronic ...
Hart Simon P, Wallace, William A., McFarlane, Pauline, Bournazos, Stylianos, Bournazos Stylianos, Alexander, Karen M, Karen M Alexander, Jacob Grinfeld, William A Wallace, Simpson A John, Hirani, Nikhil, McFarlane Pauline, Pauline McFarlane, Grinfeld Jacob, Grinfeld, Jacob, Hirani Nikhil, Simpson, A John, John T Murchison, Nikhil Hirani, Wallace William A, Hart, Simon P, Simpson, A. John, Dransfield, Ian, Stylianos Bournazos, Murchison John T, Alexander Karen M, Murchison, John T, Wallace, William, Ian Dransfield, Dransfield Ian, A John Simpson, Simon P Hart   +31 more
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Pirfenidone in idiopathic pulmonary fibrosis:expert panel discussion on the management of drug-related adverse events [PDF]

, 2014
Pirfenidone is currently the only approved therapy for idiopathic pulmonary fibrosis, following studies demonstrating that treatment reduces the decline in lung function and improves progression-free survival.
Per M. Hellström, Groves, Richard, Michael Kreuter, Toby M. Maher, Maher, Toby M, Dewint, P. (Pieter), Sarafidis, A. (Alexandre), Vancheri, C. (Carlo), Egan, Jim JJ, Bendstrup, Elisabeth, Maher, T.M. (Toby), Bendstrup, E. (Elisabeth), Sarafidis, Alexandre, Egan, Jim J J, Vancheri, Carlo, Jim J. J. Egan, Costabel, Ulrich, Ferguson, James, Vincent Cottin, Nordlind, K. (Klas), Cottin, V. (Vincent), Hellström, Per M, Maher, Toby M., Carlo Vancheri, Richard Groves, Groves, R. (Richard), Costabel, U., Klas Nordlind, Dewint, Pieter, Nordlind, Klas, Cottin, Vincent, Ulrich Costabel, Ferguson, J.J. (James), Hellström, A.-L., Alexandre Sarafidis, Pieter Dewint, Egan, Jim J. J., Elisabeth Bendstrup, Kreuter, M. (Michael), Maria Molina-Molina, Molina-Molina, M. (Maria), James Ferguson, Kreuter, Michael, Egan, J.J.J. (Jim J.), Molina-Molina, Maria, Hellström, Per M., Hellström, Per M.,   +46 more
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Magnetic resonance imaging as a non-invasive tool to investigate pulmonary and renal fibrosis in small rodents : method and readout validation, animal model optimization, and substance testing [PDF]

, 2015
Pulmonary fibrosis, an end result of various types of lung damage including interstitial pneumonia and respiratory bronchiolitis (Gross and Hunninghake, 2001; Katzenstein and Myers, 1998; Lazenby et al., 1990) is a lethal disease characterized by ...
Egger, Christine
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Promoter variants in tissue inhibitor of metalloproteinase-3 (TIMP-3) protect against susceptibility in pigeon breeders' disease. [PDF]

, 2004
BACKGROUND: Tissue inhibitors of metalloproteinases (TIMPs) play a major role in extracellular matrix turnover in the lung. However, in chronic lung disorders such as idiopathic pulmonary fibrosis (IPF) and pigeon breeders' disease (PBD), TIMPs may ...
Briggs, L, Montaño, MM, Pardo, A, Estrada, A, Laurent, GJ, Selman, M, Hill, MR, Pardo-Cemo, Annie   +7 more
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Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E-2 production [PDF]

, 2004
Levels of prostaglandin E-2 (PGE(2)), a potent inhibitor of fibroblast function, are decreased in the lungs of patients with pulmonary fibrosis, which has been shown to be because of limited expression of cyclooxygenase-2 (COX-2).
McAnulty, R J, Martyn L. Foster, Laurent, G J, Rebecca J. Hodges, R. Gisli Jenkins, Geoffrey J. Bellingan, Jenkins, R G, Bellingan, GJ, Hart, S L, Laurent, GJ, Jenkins, RG, Bottoms, SE, Copeman, DM, Bottoms, S E, Geoffrey J. Laurent, Nanthakumar, C B, Foster, ML, Wheeler-Jones, C P D, Stephen L. Hart, Hodges, RJ, Wheeler-Jones, CPD, Robin J. McAnulty, Bellingan, G J, McAnulty, RJ, Nanthakumar, CB, Inst Child Hlth, Foster, M L, Stephen E. Bottoms, Copeman, D M, Caroline P.D. Wheeler-Jones, Carmel B. Nanthakumar, Hart, SL, Merck Sharp & Dohme, Hodges, R J, UCL, Danielle M. Copeman   +35 more
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Rare and common variants in KIF15 contribute to genetic risk of idiopathic pulmonary fibrosis [PDF]

, 2022
RATIONALE: Genetic studies of Idiopathic Pulmonary Fibrosis (IPF) have improved our understanding of this disease, but not all causal loci have been identified.
Newton, Chad A, Povysil, Gundula, Martinez, Fernando J, Garcia, Joseph A, Petrovski, Slavé, Li, Qi, Maher, Toby M, Garcia, Christine Kim, Kobeissy, Philippe H, Raghu, Ganesh, Amelotte, Mason, Goldstein, David B, Haefliger, Carolina, Wang, Binhan, Molyneaux, Philip L, Jaouadi, Hager, Noth, Imre, Todd, Jamie L, Palmer, Scott M, Platt, Adam, Zhang, David   +20 more
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Idiopathic Pulmonary Fibrosis: Treatment and Prognosis [PDF]

, 2015
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with a prognosis that can be worse than for many cancers. The initial stages of the condition were thought to mainly involve chronic inflammation; therefore, corticosteroids and ...
Tetsu Kobayashi, Hajime Fujimoto, Arata Azuma   +2 more
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Diffuse pulmonary hemosiderosis after exposure to pesticides - A case report [PDF]

, 1998
This report describes the clinical, radiological, microscopical and ligandohistochemical findings in a 17-year-old woman who suffered from an acute onset of pulmonary hemosiderosis after inhalation of pesticides used for the cultivation of strawberries ...
Kayser, Klaus, Gabius, Hans-Joachim, Slodkowska, Janina, Waitr, Elzbieta, Altiner, Mithat, Plodziszewska, Monika   +5 more
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