Results 101 to 110 of about 61,250 (205)
Myopathology and Immune Profile of Granulomatous Myositis in Sarcoid Myopathy
SaM is characterised by endomysial and perimysial granulomatous inflammation frequently extending to the fascia, endomysial fibrosis, muscle fibre atrophy, variation in muscle fibre size and capillary thickening. Chitinase 1 represents a pure giant cell marker in SaM.
Nikolas Ruffer+22 more
wiley +1 more source
Targeting E3 ubiquitin ligases: a new frontier in idiopathic pulmonary fibrosis treatment. [PDF]
Zhang K, Yuan H, Shi L.
europepmc +1 more source
The AhR Is a Critical Regulator of the Pulmonary Response to Cannabis Smoke
AhR activation coordinates the pulmonary response to cannabis smoke. Inhalation of cannabis smoke disrupts epithelial integrity and promotes inflammation. AhR is activated by cannabis smoke and regulates cytoskeletal structure, detoxification, antioxidant, and immune pathways.
Emily T. Wilson+7 more
wiley +1 more source
Role of Immune Cells in Mediating the Effect of Hypothyroidism on Idiopathic Pulmonary Fibrosis. [PDF]
Liu Z+8 more
europepmc +1 more source
Epstein–Barr virus and wild p53 in idiopathic pulmonary fibrosis
She Lok+4 more
openalex +1 more source
Inhibition of autotaxin activity with IOA‐289 decreases fibrosis in mouse E0771 breast tumors
What's new? Lysophosphatidate is one of the critical mediators of fibrosis formation in the tumor microenvironment, which hinders immune surveillance and therapy. Building on their previous finding that blocking lysophosphatidate production with the autotaxin inhibitor, IOA‐289 decreased tumor growth by approximately 60%, here the authors show that ...
Xiaoyun Tang+4 more
wiley +1 more source
Anti‐RuvBL1/2 Antibodies in Scleromyositis: A Clinicopathological Report of Two Cases
We report two patients with scleromyositis with anti‐RuvBL1/2 antibodies, recently identified rare autoantibodies associated with older age at onset, diffuse sclerodactyly, skeletal and cardiac myositis, and interstitial lung disease (ILD). Both patients showed sclerodactyly and skeletal myositis.
Yuki Imai+6 more
wiley +1 more source
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen+10 more
wiley +1 more source