Results 101 to 110 of about 209,966 (285)

Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis

European Respiratory Journal, 2020
Galectin (Gal)-3 is a profibrotic β-galactoside-binding lectin that plays a key role in the pathogenesis of idiopathic pulmonary fibrosis (IPF) and IPF exacerbations. TD139 is a novel and potent small-molecule inhibitor of Gal-3.
N. Hirani, A. C. Mackinnon, L. Nicol, P. Ford, H. Schambye, A. Pedersen, Ulf J. Nilsson, H. Leffler, T. Sethi, Susan Tantawi, Lise Gavelle, Robert J. Slack, R. Mills, Utsa Karmakar, Duncan C. Humphries, F. Zetterberg, Lucy Keeling, Lyn Paul, P. Molyneaux, Feng Li, W. Funston, Ian A. Forrest, A. J. Simpson, Michael A Gibbons, T. Maher   +24 more
semanticscholar   +1 more source

Epidemiology of idiopathic pulmonary fibrosis

Clinical Epidemiology, 2013
Brett Ley, Harold R Collard Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California San Francisco, San Francisco, California, USA Abstract: Idiopathic pulmonary fibrosis is a chronic fibrotic lung disease of ...
Ley B, Collard HR
doaj  

Diffuse pulmonary ossification associated with fibrosing interstitial lung disease

Respiratory Medicine Case Reports, 2019
Diffuse pulmonary ossification (DPO) is a rare condition that presents with metaplastic mature bone formation in the pulmonary parenchyma. DPO is usually associated with cardiovascular or respiratory disease.
Badreeddine Alami, Bouchra Amara, Meryem Haloua, Moulay Youssef Alaoui Lmrani, Mounia Serraj, Meryem Boubou, Mustapha Maaroufi   +6 more
doaj   +1 more source

Mesenchymal Stem Cell-Derived Extracellular Vesicles as Idiopathic Pulmonary Fibrosis Microenvironment Targeted Delivery [PDF]

, 2022
Lu Sang, Xiaoqin Guo, Haojun Fan, Jie Shi, Shike Hou, Qi Lv   +5 more
openalex   +1 more source

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis [PDF]

, 2012
Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies and characterized by excessive collagen deposition and subsequent fibrosis.
Anderson, G.P., Bozinovski, S., Ernst, M.R., Jarnicki, A.G., Jones, J., Knight, D.A., Lau, H.L., Laurent, G.J., McAnulty, R.J., McKenzie, B.S., Mutsaers, S.E., O'Donoghue, R.J.J., Prêle, C.M., Richards, C.D., Rose-John, S., Stumbles, P.A., Thiem, S., Vlahos, R., Wang, B., Zhu, H.J.   +19 more
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Diagnostic test interpretation and referral delay in patients with interstitial lung disease. [PDF]

, 2019
BACKGROUND:Diagnostic delays are common in patients with interstitial lung disease (ILD). A substantial percentage of patients experience a diagnostic delay in the primary care setting, but the factors underpinning this observation remain unclear.
Adegunsoye, Ayodeji, Boctor, Noelle, Chung, Jonathan H, DiGeronimo, Ryan, Kadoch, Michael, Lafond, Elyse, Oldham, Justin M, Pan, Isabella, Pritchard, David, Pugashetti, Janelle Vu, Sarma, Nandini, Strek, Mary   +11 more
core   +1 more source

Growth factors in idiopathic pulmonary fibrosis: relative roles [PDF]

, 2001
Treatment of idiopathic pulmonary fibrosis patients has evolved very slowly; the fundamental approach of corticosteroids alone or in combination with other immunosuppressive agents has had little impact on long-term survival.
Allen, JT, Spiteri, MA
core   +3 more sources

DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis

Cells, 2019
Idiopathic pulmonary fibrosis (IPF) has been linked to chronic lung inflammation. Drosha ribonuclease III (DROSHA), a class 2 ribonuclease III enzyme, plays a key role in microRNA (miRNA) biogenesis.
Soo Jung Cho, Kyoung Sook Hong, Ji Hun Jeong, Mihye Lee, Augustine M. K. Choi, Heather W. Stout-Delgado, Jong-Seok Moon   +6 more
doaj   +1 more source

Periostin as a biomarker of airway inflammation [PDF]

, 2016
No abstract ...
Johnstone, Steven, McSharry, Charles
core   +1 more source

P16‐80: Differential source of early phase discontinuation between pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis [PDF]

, 2021

openalex   +1 more source