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Identifying potential biomarkers of idiopathic pulmonary fibrosis through machine learning analysis
Idiopathic pulmonary fibrosis (IPF) is the most common and serious type of idiopathic interstitial pneumonia, characterized by chronic, progressive, and low survival rates, while unknown disease etiology.
Zenan Wu +7 more
doaj +2 more sources
Idiopathic pulmonary fibrosis is a prototype of chronic, progressive, and fibrotic lung disease. Healthy tissue is replaced by altered extracellular matrix and alveolar architecture is destroyed, which leads to decreased lung compliance, disrupted gas exchange, and ultimately respiratory failure and death.
L. Richeldi, H. Collard, Mark G. Jones
semanticscholar +14 more sources
Idiopathic pulmonary fibrosis [PDF]
Idiopathic pulmonary fibrosis (IPF) is a non-neoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known provocation.
Noble Paul W, Meltzer Eric B
doaj +4 more sources
Regulatory Immune Cells in Idiopathic Pulmonary Fibrosis: Friends or Foes?
The immune system is receiving increasing attention for interstitial lung diseases, as knowledge on its role in fibrosis development and response to therapies is expanding. Uncontrolled immune responses and unbalanced injury-inflammation-repair processes
Chiel van Geffen +10 more
doaj +2 more sources
Epidemiology of idiopathic pulmonary fibrosis
Brett Ley, Harold R Collard Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California San Francisco, San Francisco, California, USA Abstract: Idiopathic pulmonary fibrosis is a chronic fibrotic lung disease of ...
Ley B, Collard HR
doaj +8 more sources
Idiopathic pulmonary fibrosis [PDF]
Idiopathic pulmonary fibrosis is a progressive lung disease that carries a poor prognosis and for which there are no effective therapies. Although the excessive deposition of extracellular matrix, combined with evidence of recurrent injury to the alveolar epithelium, are well-described there is a pressing need to understand these processes better at a ...
Moira K. B. Whyte, Zhe Hui Hoo
openaire +5 more sources
Idiopathic pulmonary fibrosis: current diagnosis and treatment [PDF]
Idiopathic pulmonary fibrosis (IPF) is a devastating chronic lung disease without a clear recognizable cause. IPF has been at the forefront of new diagnostic algorithms and treatment developments that led to a shift in patients’ care in the past decade ...
Alexandre Franco Amaral +2 more
doaj +1 more source
Background This American Thoracic Society, European Respiratory Society, Japanese Respiratory Society, and Asociación Latinoamericana de Tórax guideline updates prior idiopathic pulmonary fibrosis (IPF) guidelines and addresses the progression of ...
G. Raghu +40 more
semanticscholar +1 more source
Global incidence and prevalence of idiopathic pulmonary fibrosis
Background Idiopathic pulmonary fibrosis (IPF) is a progressive debilitating lung disease with considerable morbidity. Heterogeneity in epidemiologic studies means the full impact of the disease is unclear.
T. Maher +7 more
semanticscholar +1 more source

