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Idiopathic pulmonary fibrosis [PDF]
Orphanet Journal of Rare Diseases, 2008 Idiopathic pulmonary fibrosis (IPF) is a non-neoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known provocation.
Noble Paul W, Meltzer Eric B
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Idiopathic Pulmonary Fibrosis.
La Presse Médicale, 2023 Idiopathic pulmonary fibrosis (IPF) is a progressive devastating lung disease with substantial morbidity. It is associated with cough, dyspnea and impaired quality of life. If left untreated, IPF has a median survival of 3 years. IPF affects ∼3 million people worldwide, with increasing incidence in older patients. The current concept of pathogenesis is
T. Koudstaal, M. Wijsenbeek
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Medicina Clínica (English Edition), 2017 Idiopathic pulmonary fibrosis is a fibrosing interstitial pneumonia associated with the radiological and/or histological pattern of usual interstitial pneumonia. Its aetiology is unknown, but probably comprises the action of endogenous and exogenous micro-environmental factors in subjects with genetic predisposition.
L. Richeldi, H. Collard, Mark G. Jones
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[Idiopathic pulmonary fibrosis].
Medecine sciences : M/S, 2022 38;6 ...
Hennion, Nathan +4 more
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Idiopathic pulmonary fibrosis [PDF]
Thorax, 2011 Idiopathic pulmonary fibrosis is a progressive lung disease that carries a poor prognosis and for which there are no effective therapies. Although the excessive deposition of extracellular matrix, combined with evidence of recurrent injury to the alveolar epithelium, are well-described there is a pressing need to understand these processes better at a ...
Zhe Hui, Hoo, Moira K B, Whyte
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Telomerase and idiopathic pulmonary fibrosis
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2011 Idiopathic pulmonary fibrosis (IPF) is the most common manifestation of telomere-mediated disorders. Germline mutations in the essential telomerase genes, hTERT and hTR, are the causal genetic defect in up to one-sixth of pulmonary fibrosis families. The presence of telomerase mutations in this subset is significant for clinical decisions as affected ...
Mary Armanios
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Frontiers in Medicine, 2022 Patients with idiopathic pulmonary fibrosis are screened for circulating autoantibodies as part of the initial interstitial lung disease workup. Management of seropositive idiopathic pulmonary fibrosis is currently considered no different than that of ...
Paraskevi Kirgou +8 more
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BMC Pulmonary Medicine, 2023 Background Following COVID-19 infection, some patients acquired lung injury and fibrosis. Idiopathic pulmonary fibrosis is characterized by lung fibrosis.
Deniz Kızılırmak +3 more
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The Role of DNA Damage and Repair in Idiopathic Pulmonary Fibrosis
Antioxidants, 2022 The mortality rate of idiopathic pulmonary fibrosis (IPF) increases yearly due to ineffective treatment. Given that the lung is exposed to the external environment, it is likely that oxidative stress, especially the stimulation of DNA, would be of ...
Jiahui Zhu +10 more
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