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Idiopathic pulmonary fibrosis: Current and future treatment
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease characterized by dry cough, fatigue, and progressive exertional dyspnea. Lung parenchyma and architecture is destroyed, compliance is lost, and gas exchange is compromised in this ...
Daniel S. Glass+6 more
semanticscholar +1 more source
Fibro-CoSANet: Pulmonary Fibrosis Prognosis Prediction using a Convolutional Self Attention Network [PDF]
Idiopathic pulmonary fibrosis (IPF) is a restrictive interstitial lung disease that causes lung function decline by lung tissue scarring. Although lung function decline is assessed by the forced vital capacity (FVC), determining the accurate progression of IPF remains a challenge. To address this challenge, we proposed Fibro-CoSANet, a novel end-to-end
arxiv +1 more source
Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis.
BACKGROUND Phosphodiesterase 4 (PDE4) inhibition is associated with antiinflammatory and antifibrotic effects that may be beneficial in patients with idiopathic pulmonary fibrosis.
L. Richeldi+9 more
semanticscholar +1 more source
Targeting Oxidative Stress as a Therapeutic Approach for Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis within the alveolar wall that are not due to infection or cancer ...
Cristina Estornut+4 more
semanticscholar +1 more source
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease that poses a significant challenge to medical professionals due to its increasing incidence and prevalence coupled with the limited understanding of its underlying molecular ...
Shichen Zhang+7 more
doaj +1 more source
Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis
Similarly to idiopathic pulmonary fibrosis (IPF), other interstitial lung diseases can develop progressive pulmonary fibrosis (PPF) characterized by declining lung function, a poor response to immunomodulatory therapies, and early mortality.
Gabrielle Y. Liu+2 more
semanticscholar +1 more source
Cough in idiopathic pulmonary fibrosis [PDF]
Many patients with idiopathic pulmonary fibrosis (IPF) complain of chronic refractory cough. Chronic cough is a distressing and disabling symptom with a major impact on quality of life. During recent years, progress has been made in gaining insight into the pathogenesis of cough in IPF, which is most probably “multifactorial” and influenced by ...
Van Manen MJ+6 more
openaire +6 more sources
Aims This study evaluated the acceptability of a dignity‐centred palliative care programme for people with idiopathic pulmonary fibrosis by converging perceptions of living with idiopathic pulmonary fibrosis qualitative data and quantitative data. Design
Yasuko Igai, Sarah E. Porter
doaj +1 more source
Human lung single-cell atlas reveals the complexity and diversity of aberrant cellular populations in pulmonary fibrosis. We provide a single-cell atlas of idiopathic pulmonary fibrosis (IPF), a fatal interstitial lung disease, by profiling 312,928 cells
T. Adams+17 more
semanticscholar +1 more source
Immune dysregulation as a driver of idiopathic pulmonary fibrosis.
Idiopathic pulmonary fibrosis (IPF) affects hundreds of thousands of people worldwide, reducing their quality of life and leading to death from respiratory failure within years of diagnosis.
K. Shenderov+3 more
semanticscholar +1 more source