Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]
Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
core +3 more sources
Is It Idiopathic Pulmonary Fibrosis or Not? [PDF]
Pulmonary fibrosis is not uncommon. Usual interstitial pneumonitis (UIP)/idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic pulmonary fibrotic diseases and has the worst prognosis with a mean life expectancy of 3.8 years.
Genta Ishikawa+2 more
openaire +3 more sources
Multiscale modelling of reversed Potts shunt as a potential palliative treatment for suprasystemic idiopathic pulmonary artery hypertension in children [PDF]
Reversed Potts shunt (PS) was suggested as palliation for patients with suprasystemic pulmonary arterial hypertension (PAH) and right ventricular (RV) failure. PS, however, can result in poorly understood mortality. Here, a patient-specific geometrical multiscale model of PAH physiology and PS is developed for a paediatric PAH patient with stent-based ...
arxiv +1 more source
Akt1 regulates pulmonary fibrosis via modulating IL-13 expression in macrophages
Idiopathic pulmonary fibrosis is a progressive interstitial pneumonia characterised by fibroblast accumulation, collagen deposition and extracellular matrix (ECM) remodelling.
Yunjuan Nie+7 more
doaj +1 more source
IDIOPATHIC PULMONARY FIBROSIS. CORRECTION OF ERRORS
Substantial changes have been recently made in the concept of the diagnosis of idiopathic pulmonary fibrosis. The concept of disease pathogenesis and the pathomorphologic criteria for diagnosing usual interstitial pneumonia have been revised.
A. L. Yudin+2 more
doaj +1 more source
Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression. [PDF]
Targeting activated fibroblasts, including myofibroblast differentiation, has emerged as a key therapeutic strategy in patients with idiopathic pulmonary fibrosis (IPF).
Chen, Ching-Hsien+7 more
core +2 more sources
Objectives: Idiopathic pulmonary fibrosis (IPF) (J84.1 by the International Statistical Classification of Diseases and Related Health Problems, 10th revision – ICD-10) is a rare disease of unknown cause.
Ewa Niewiadomska+2 more
doaj +1 more source
A review of current studies on cellular and molecular mechanisms underlying pulmonary fibrosis induced by chemicals [PDF]
Several studies showed that the inflammatory and fibrotic responses induced by polyhexamethylene guanidine phosphate (PHMG-p) were similar to those observed for idiopathic pulmonary fibrosis in South Korea in 2011.
Ha Ryong Kim+2 more
doaj +1 more source
Management of Idiopathic Pulmonary Fibrosis [PDF]
Idiopathic pulmonary fibrosis (IPF) is a deadly progressive lung disease without an effective standard treatment approach. Because of the complexity and uncertainties of IPF treatment, therapeutic decisions need to be tailored to the individual patient, after discussing the potential benefits and pitfalls.
CERRI, Stefania+3 more
openaire +6 more sources
Survival Analysis for Idiopathic Pulmonary Fibrosis using CT Images and Incomplete Clinical Data [PDF]
Idiopathic Pulmonary Fibrosis (IPF) is an inexorably progressive fibrotic lung disease with a variable and unpredictable rate of progression. CT scans of the lungs inform clinical assessment of IPF patients and contain pertinent information related to disease progression.
arxiv