Results 31 to 40 of about 204,699 (375)

Treatment of Idiopathic Pulmonary Fibrosis [PDF]

Cureus, 2021
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial pneumonia of unknown cause, occurring in adults and limited to the lungs. In the past, treatment was aimed at minimizing inflammation and slowing the progression of inflammation to fibrosis. However, the underlying lesion in IPF may be more fibrotic than inflammatory,
Gregory Becker, Sherif T Abuserewa, Richard Duff   +2 more
openaire   +3 more sources

Development of a Consensus Statement for the Definition, Diagnosis, and Treatment of Acute Exacerbations of Idiopathic Pulmonary Fibrosis Using the Delphi Technique. [PDF]

, 2015
© 2015, The Author(s).Introduction: There is a lack of agreed and established guidelines for the treatment of acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF).
Bennett, BM, Hoyles, RK, Maher, TM, Mathieson, N, Ochiai, Y, Parfrey, H, Turnbull, A, Whyte, MK, Williamson, N   +8 more
core   +2 more sources

Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis

British medical journal, 2022
Similarly to idiopathic pulmonary fibrosis (IPF), other interstitial lung diseases can develop progressive pulmonary fibrosis (PPF) characterized by declining lung function, a poor response to immunomodulatory therapies, and early mortality.
Gabrielle Y. Liu, G. S. Budinger, J. Dematte   +2 more
semanticscholar   +1 more source

Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]

, 2010
Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica, Dumitrascu, Rio, Eickelberg, Oliver, Grimminger, Friedrich, Königshoff, Melanie, Reiter, Rudolf, Schermuly, Ralph Theo, Seeger, Werner, Udalov, Sergey   +8 more
core   +1 more source

Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy - the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial [PDF]

, 2020
Compelling data have linked disease progression in patients with idiopathic pulmonary fibrosis (IPF) with lung dysbiosis and the resulting dysregulated local and systemic immune response.
A Mishra, AW Brown, B Ley, BA Karimi-Shah, BT Baxter, CJ Ryerson, DG Pankratz, DJ Lederer, G Raghu, G Raghu, H Scheper, HR Collard, J Andrade, J Coast, J Coast, K Loudon, K Loudon, KA Getz, KD Brandt, KE Thorpe, KF Schulz, L Richeldi, L Shulgina, LB Krupp, M Fralick, M Hammond, MA Fischl, MA Perazella, MO Paterniti, MT Durheim, P Bhattacharyya, PL Molyneaux, PL Molyneaux, PL Molyneaux, R Dal-Ré, RM Califf, RM du Bois, SD Nathan, SS Birring, T Katsuyama, TE King Jr, VA Varney, WS Jones, Y Huang   +43 more
core   +1 more source

Pirfenidone for Idiopathic Pulmonary Fibrosis and Beyond

Cardiac failure review, 2022
Pirfenidone (PFD) slows the progression of idiopathic pulmonary fibrosis (IPF) by inhibiting the exaggerated fibrotic response and possibly through additional mechanisms, such as anti-inflammatory effects.
Alberto Aimo, G. Spitaleri, D. Nieri, L. Tavanti, C. Meschi, G. Panichella, J. Lupón, F. Pistelli, L. Carrozzi, A. Bayés‐Genís, M. Emdin   +10 more
semanticscholar   +1 more source

Acute worsening of native lung fibrosis after single lung transplantation for pulmonary fibrosis: two case reports

Journal of Medical Case Reports, 2022
Background In patients receiving single lung transplantation for idiopathic pulmonary fibrosis, worsening of fibrosis of the native lung is usually progressive over time, with no significant effects on gas exchange.
Tiphaine Goletto, Sixtine Decaux, Vincent Bunel, Gaëlle Weisenburger, Jonathan Messika, Samer Najem, Chahine Medraoui, Cendrine Godet, Marie Pierre Debray, Brice Lortat-Jacob, Pierre Mordant, Yves Castier, Lila Bouadma, Raphael Borie, Hervé Mal   +14 more
doaj   +1 more source

Quantitative computed tomography predicts outcomes in idiopathic pulmonary fibrosis

Respirology (Carlton South. Print), 2022
Prediction of disease course in patients with progressive pulmonary fibrosis remains challenging. The purpose of this study was to assess the prognostic value of lung fibrosis extent quantified at computed tomography (CT) using data‐driven texture ...
S. Humphries, J. Mackintosh, H. Jo, S. Walsh, Mario Silva, L. Calandriello, Sally Chapman, Samantha J Ellis, I. Glaspole, N. Goh, C. Grainge, P. Hopkins, G. Keir, Y. Moodley, P. Reynolds, E. Walters, D. Baraghoshi, A. Wells, D. Lynch, T. Corte   +19 more
semanticscholar   +1 more source

Is It Idiopathic Pulmonary Fibrosis or Not? [PDF]

The Journal of the American Board of Family Medicine, 2018
Pulmonary fibrosis is not uncommon. Usual interstitial pneumonitis (UIP)/idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic pulmonary fibrotic diseases and has the worst prognosis with a mean life expectancy of 3.8 years.
Genta Ishikawa, Mary Salvatore, Maria Padilla   +2 more
openaire   +3 more sources

Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations [PDF]

, 2014
BACKGROUND: Previous studies investigating a genetic basis for idiopathic pulmonary fibrosis (IPF) have focused on resequencing single genes in IPF kindreds or cohorts to determine the genetic contributions to IPF.
Coghlan, Meghan A, Cole, F. Sessions, Hamvas, Aaron, Huang, Howard J, Mitra, Robi D, Russell, Tonya D, Shifren, Adrian, Wegner, Daniel J, Zhang, Qunyuan   +8 more
core   +3 more sources