Results 31 to 40 of about 209,966 (285)

Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report [PDF]

, 2016
Immunosuppressive therapy has been-until the recent release of new guidelines on diagnosis and management-the recommended treatment for idiopathic pulmonary fibrosis.
CERRI, Stefania, LUPPI, Fabrizio, RICHELDI, Luca, SGALLA, Giacomo   +3 more
core   +1 more source

Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]

, 2015
Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
core   +3 more sources

Targeting Oxidative Stress as a Therapeutic Approach for Idiopathic Pulmonary Fibrosis

Frontiers in Pharmacology, 2022
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis within the alveolar wall that are not due to infection or cancer ...
C. Estornut, J. Milara, María Amparo Bayarri, N. Belhadj, J. Cortijo   +4 more
semanticscholar   +1 more source

Rethinking Idiopathic Pulmonary Fibrosis

Clinics in Chest Medicine, 2021
Idiopathic pulmonary fibrosis (IPF) is a devastating disease for patients and their loved ones. Since initial efforts to characterize this disease in the 1960s, understanding of IPF has evolved considerably. Such evolution has continually challenged prior diagnostic and treatment paradigms, ushering in an era of higher confidence diagnoses with less ...
Oldham, Justin M, Vancheri, Carlo
openaire   +2 more sources

Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis.

New England Journal of Medicine, 2014
BACKGROUND Nintedanib (formerly known as BIBF 1120) is an intracellular inhibitor that targets multiple tyrosine kinases. A phase 2 trial suggested that treatment with 150 mg of nintedanib twice daily reduced lung-function decline and acute exacerbations
L. Richeldi, R. D. du Bois, G. Raghu, A. Azuma, K. Brown, U. Costabel, V. Cottin, K. Flaherty, D. Hansell, Y. Inoue, D. S. Kim, M. Kolb, A. Nicholson, P. Noble, M. Selman, H. Taniguchi, M. Brun, F. Le Maulf, M. Girard, S. Stowasser, R. Schlenker‐Herceg, B. Disse, H. Collard   +22 more
semanticscholar   +1 more source

Imaging diagnosis-computed tomography of traction bronchiectasis secondary to pulmonary fibrosis in a Patterdale Terrier [PDF]

, 2016
An 8-year-old, Patterdale terrier was referred for evaluation of tachypnoea, exercise intolerance, and weight loss. Computed tomographic images showed pneumomediastinum, diffuse pulmonary ground glass opacity, and marked dilatation of peripheral bronchi,
Fitzgerald, E, Lamb, C R, Priestnall, S L   +2 more
core   +2 more sources

Immune dysregulation as a driver of idiopathic pulmonary fibrosis.

Journal of Clinical Investigation, 2021
Idiopathic pulmonary fibrosis (IPF) affects hundreds of thousands of people worldwide, reducing their quality of life and leading to death from respiratory failure within years of diagnosis.
K. Shenderov, S. Collins, J. Powell, M. Horton   +3 more
semanticscholar   +1 more source

A sigmoidal fit for pressure-volume curves of idiopathic pulmonary fibrosis patients on mechanical ventilation: clinical implications

Clinics, 2011
OBJECTIVE: Respiratory pressure-volume curves fitted to exponential equations have been used to assess disease severity and prognosis in spontaneously breathing patients with idiopathic pulmonary fibrosis.
Juliana C. Ferreira, Fabio E. M. Benseñor, Marcelo J. J. Rocha, Joao M. Salge, R. Scott Harris, Atul Malhotra, Ronaldo A. Kairalla, Robert M. Kacmarek, Carlos R. R. Carvalho   +8 more
doaj   +1 more source

Acute worsening of native lung fibrosis after single lung transplantation for pulmonary fibrosis: two case reports

Journal of Medical Case Reports, 2022
Background In patients receiving single lung transplantation for idiopathic pulmonary fibrosis, worsening of fibrosis of the native lung is usually progressive over time, with no significant effects on gas exchange.
Tiphaine Goletto, Sixtine Decaux, Vincent Bunel, Gaëlle Weisenburger, Jonathan Messika, Samer Najem, Chahine Medraoui, Cendrine Godet, Marie Pierre Debray, Brice Lortat-Jacob, Pierre Mordant, Yves Castier, Lila Bouadma, Raphael Borie, Hervé Mal   +14 more
doaj   +1 more source

Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

Science Advances, 2020
Human lung single-cell atlas reveals the complexity and diversity of aberrant cellular populations in pulmonary fibrosis. We provide a single-cell atlas of idiopathic pulmonary fibrosis (IPF), a fatal interstitial lung disease, by profiling 312,928 cells
T. Adams, J. Schupp, S. Poli, Ehab A. Ayaub, N. Neumark, F. Ahangari, S. Chu, B. Raby, G. DeIuliis, Michael Januszyk, Qiaonan Duan, H. Arnett, Asim Siddiqui, G. Washko, R. Homer, Xiting Yan, I. Rosas, N. Kaminski   +17 more
semanticscholar   +1 more source